Botanical species · safety record

Ledum palustre

The EFSA Compendium of Botanicals holds 10 constituent measurements and 1 adverse-effect record for Ledum palustre. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Ledum palustre L.

10Constituent measurements

1Safety records

4Cited sources

115Licensed products (Canada)

Also recorded as

Ledum palustre var. palustre
Rhododendron tomentosum Harmaja

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 115 licensed products naming Ledum palustre as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Branch(es)
Brindille feuillue
Dried tips of twigs
Flower
Fresh leaving branches
Herb(s)
Leaf/Leaves
Leafy twigs

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
(-)-globulol	Shoot	Essential oil	≤ 18.3 Percent	GC-FID	Resolve DOI
(-)-globulol	Shoot	Essential oil	≥ 11.8 Percent	GC-FID	Resolve DOI
Myrcene	Shoot	Essential oil	≤ 2.8 Percent	GC-FID	Resolve DOI
Myrcene	Shoot	Essential oil	≥ 1 Percent	GC-FID	Resolve DOI
(-)-globulol	Leaves	Essential oil	26.7 Percent	Unspecified	No resolvable identifier
(-)-globulol	Seed	Essential oil	27 Percent	Unspecified	No resolvable identifier
Coumarins	Unspecified	—	—	Unspecified	No resolvable identifier
Myrcene	Aerial part of plants	Essential oil	≥ 1.2 Percent	GC-MS	No resolvable identifier
Myrcene	Aerial part of plants	Essential oil	≤ 30.8 Percent	GC-MS	No resolvable identifier
Scopoletin	Unspecified	Solvent extraction	20 Microgram/gram	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic: central nervous system	Leaves	Essential oil (as part-nature)	—	Not reported	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Klokova, M. V., Serykh, E. A., Berezovskaya, T. P. Ledum genus coumarins. Khimiya Prirodnykh Soedinenii, 1982.
Waksmundzka-Hajnos, M., Smolarz, H.D., Matysik, G. Quantitative determination of scopoletin in some herbs from the Ericaceae family by thin-layer chromatography and densitometry. Acta poloniae pharmaceutica - drug research, 1997, vol. 54, no. 3, p. 237-241.
Raal, Ain., Orav, Anne., Gretchushnikova, Tatjana. Composition of the essential oil of the Rhododendron tomentosum Harmaja from Estonia. NATURAL PRODUCT RESEARCH, 2014, vol. 28, no. 14, p. 1091-1098. DOI
Hjelt, Edward I. Ledum-camphor. Berichte der deutschen chemischen gesellschaft, 1895, p. 3087-3089.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature