Botanical species · safety record

Leonotis nepetifolia

The EFSA Compendium of Botanicals holds 24 constituent measurements and 1 adverse-effect record for Leonotis nepetifolia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Leonotis nepetifolia (L.) R.Br.

24Constituent measurements

1Safety records

5Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Coumarin	Live plants	—	—	Unspecified	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpene alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Labdane diterpenes	Live plants	—	—	Unspecified	Resolve DOI
Eugenol	Leaves	Essential oil	4.9 Percent	GC-MS	No resolvable identifier
Methylisoeugenol	Leaves	Essential oil	5.8 Percent	GC-MS	No resolvable identifier
P-menth-1-en-3-one	Leaves	Essential oil	6.4 Percent	GC-MS	No resolvable identifier
P-mentha-1,4(8)-dien-3-one	Leaves	Essential oil	4.6 Percent	GC-MS	No resolvable identifier
Piperitenone oxide	Leaves	Essential oil	5.4 Percent	GC-MS	No resolvable identifier
Tannins	Aerial part of plants	Drying (dehydration)	—	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Reproductive	Uterus	Leaves	Raw, no heat treatment	Human (as organism)	Other	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Thoppil, John Ernest., Jose, Joseph. Chromosome architecture and major essential oil constituents in Leonotis nepetifolia (L.) Ait.f. from South India . Acta pharmaceutica (zagreb), 1995, vol. 45, no. 1, p. 25-28.
Pushpan, R., Nishteswar, K., Kumari, H. Ethno medicinal claims of Leonotis nepetifolia (L.) R. Br: A review. International journal of research in ayurveda and pharmacy, 2012, vol. 3, no. 6, p. 784-785. DOI
Li, J., Fronczek, F.R., Ferreira, D., Burandt, C.L., Setola, V., Roth, B.L., Zjawiony, J.K. Bis-spirolabdane diterpenoids from Leonotis nepetaefolia. Journal of Natural Products, 2012, vol. 75, no. 4, p. 728-734. DOI
Sobolewska, Danuta., Pasko, Pawel., Galanty, Agnieszka., Makowska-Was, Justyna., Padlo, Kinga., Wasilak, Wojciech. Preliminary phytochemical and biological screening of methanolic and acetone extracts from Leonotis nepetifolia (L.) R. Br. Journal of medicinal plants research, 2012, p. 4582-4585.
Kamatenesi-Mugisha, M., Oryem-Origa, H. Medicinal plants used to induce labour during childbirth in western Uganda. Journal of ethnopharmacology, 2007, vol. 109, no. 1, p. 1-9. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature