Botanical species · safety record

Leonurus japonicus

The EFSA Compendium of Botanicals holds 7 constituent measurements for Leonurus japonicus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Leonurus japonicus Houtt.

7Constituent measurements

0Safety records

5Cited sources

199Licensed products (Canada)

Also recorded as

Leonurus heterophyllus Sweet

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 199 licensed products naming Leonurus japonicus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh

Source material stated

Aerial parts
Dried aerial part(s)
Fruit
Herb
Herb (processed with wine)
Herb top
Herb(s)
Leaf

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Unspecified	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Labdane diterpenes	Unspecified	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Alkaloids	Aerial part of plants	Solvent extraction	0.3 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Coumarins	Unspecified	Solvent extraction	—	Chromatographic tests	No resolvable identifier
Labdane diterpenes	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Stachydrine	Aerial part of plants	Solvent extraction	≥ 0.1 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Stachydrine	Aerial part of plants	Solvent extraction	≤ 0.2 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

He, C.-J., Peng, C., Dai, O., Yang, L., Liu, J., Guo, L., Xiong, L., Liu, Z.-H. Chemical constituents from Leonurus japonicus Injection. Chinese traditional and herbal drugs, 2014, vol. 45, no. 21, p. 3048-3052. DOI
Chao, Zhi., Ma, Li-ling., Zhou, Xiu-jia. Determination of stachydrine and leonurine in Herba Leonuri by ion- pair reversed-phase high-performance liquid chromatography . . Di 1 jun yi da xue xue bao = academic journal of the first medical college of pla, 2004, vol. 24, no. 11, p. 1223-6.
Moon, Hyung-In. Three Diterpenes from Leonurus japonicus Houtt Protect Primary Cultured Rat Cortical Cells from Glutamate-induced Toxicity . Phytotherapy research, 2010, vol. 24, no. 8, p. 1256-1259. DOI
Seo, Hyun Kyu., Kim, Ju Sun., Kang, Sam Sik. Labdane Diterpenes and Flavonoids from Leonurus japonicus. Helvetica chimica acta, 2010, vol. 93, no. 10, p. 2045-2051.
Yang, Huai., Zhou, Qin-mei., Peng, Cheng., Liu, Lu-si., Xie, Xiao-fang., Xiong, Liang., Liu, Zhao-hua. Coumarins from Leonurus japonicus and their anti-platelet aggregative activity . . Zhongguo zhong yao za zhi = zhongguo zhongyao zazhi = china journal of chinese materia medica, 2014, vol. 39, no. 22, p. 4356-9.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature