Botanical species · safety record

Leonurus sibiricus

The EFSA Compendium of Botanicals holds 14 constituent measurements for Leonurus sibiricus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Leonurus sibiricus L.

14Constituent measurements

0Safety records

9Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Aerial part of plants	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Labdane diterpenes	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Labdane diterpenes	Aerial part of plants	Solvent extraction	—	GC-MS	Resolve DOI
Labdane diterpenes	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
P-coumaric acid	Roots and other underground parts	Solvent extraction	0.0526 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Phenylpropanoids	Aerial part of plants	Solvent extraction	≥ 1.58 Percent	HPLC-CAD	Resolve DOI
Phenylpropanoids	Aerial part of plants	Solvent extraction	≤ 13.01 Percent	HPLC-CAD	Resolve DOI
4-hydroxybenzoic acid	Aerial part of plants	Solvent extraction	—	—	No resolvable identifier
Isoquercitrin	Roots and other underground parts	Solvent extraction	—	Unspecified	No resolvable identifier
Isoquercitrin	Aerial part of plants	Solvent extraction	—	—	No resolvable identifier
Medioresinol	Unspecified	—	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Pinoresinol	Roots and other underground parts	Solvent extraction	—	Unspecified	No resolvable identifier
Syringaresinol	Unspecified	—	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Tannins	Aerial part of plants	—	—	Unspecified	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Zhelnov, I. I., Grazhdan, A. K. Active substances in Leonurus sibericus. Tannins. Sb. tr. posvyashch. xx-letiyu farmatsevt. fak., tomskii med. inst., tomsk, 1962, p. 125-7.
Liu, Juan., Zhou, Qin-mei., Peng, Cheng., Liu, Lu-si., Xiong, Liang., Liu, Zhao-hua. Chemical constituents and their anti-platelet aggregation activities of Leonurus sibiricus L.. Zhongchengyao, 2015, vol. 37, no. 11, p. 2439-2442.
Sitarek, Przemyslaw., Skala, Ewa., Toma, Monika., Wielanek, Marzena., Szemraj, Janusz., Nieborowska-Skorska, Malgorzata., Kolasa, Maciej., Skorski, Tomasz., Wysokinska, Halina., Sliwinski, Tomasz. A preliminary study of apoptosis induction in glioma cells via alteration of the Bax/Bcl-2-p53 axis by transformed and non-transformed root extracts of Leonurus sibiricus L. . Tumor biology, 2016, vol. 37, no. 7, p. 8753-8764. DOI
Pitschmann, Anna., Zehl, Martin., Heiss, Elke., Purevsuren, Sodnomtseren., Urban, Ernst., Dirsch, Verena M., Glasl, Sabine. Quantitation of phenylpropanoids and iridoids in insulin-sensitising extracts of Leonurus sibiricus L. (Lamiaceae) . Phytochemical analysis, 2016, vol. 27, no. 1, p. 23-31. DOI
Boalino, DM., McLean, S., Reynolds, WF., Tinto, WF. Labdane diterpenes of Leonurus sibiricus. Journal of natural products, 2004, vol. 67, no. 4, p. 714-717. DOI
Zachow, Lucimara L., Avila, Janaina M., Saldanha, Geovane A., Mostardeiro, Marco A., da Silva, Ubiratan F., Morel, Ademir F., Dalcol, Ionara I. Chemical composition and evaluation of prolyl oligopeptidase and acetylcholinesterase inhibitory activities of Leonurus Sibiricus L. from Brazil . Natural product research, 2017, vol. 31, no. 12, p. 1459-1463. DOI
Moon, Hyun Teak., Jin, Qinglong., Shin, Ji Eun., Choi, Eun Jin., Han, Hyo-Kyung., Kim, Yeong Shik., Woo, Eun-Rhan. Bis-spirolabdane-Type Diterpenoids from Leonurus sibiricus. Journal of natural products, 2010, vol. 73, no. 2, p. 123-126. DOI
Hayashi, Katsuhiko., Ikoma, Rie., Deyama, Takeshi. Phenolic compounds and iridoids from Leonurus sibiricus. Natural medicines, 2001, vol. 55, no. 5, p. 276-276.
Pan, Sheng-Ming., Ding, Hsiou-Yu., Chang, Wen-Liang., Lin, Hang-Ching. Phenols from the aerial parts of Leonurus sibiricus. Chinese pharmaceutical journal (taipei), 2006, vol. 58, no. 1, p. 35-40.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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