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Botanical species · safety record

Leptadenia reticulata

The EFSA Compendium of Botanicals holds 8 constituent measurements and 1 adverse-effect record for Leptadenia reticulata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Leptadenia reticulata (Retz.) Wight & Arn.

8Constituent measurements
1Safety records
6Cited sources
8Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 8 licensed products naming Leptadenia reticulata as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry

Source material stated

  • Root
  • Root extract
  • Stem(s)

What the records describe

Constituents measured

  • 1-phenylethanone1
  • Alkaloids1
  • Coumarins1
  • Furan derivatives1
  • P-coumaric acid1
  • Pregnane derivatives1
  • Saponins1
  • Tannins1

Plant parts

  • Live plants6
  • Leaves2
  • Aerial part of plants1

Preparations

  • Solvent extraction9

Effect types

  • Reproductive1

Target tissues

  • Uterus1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsLive plantsSolvent extraction—Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)Resolve DOI
Pregnane derivativesAerial part of plantsSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
1-phenylethanoneLeavesSolvent extraction—GC-MSNo resolvable identifier
CoumarinsLive plantsSolvent extraction—Standard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Furan derivativesLeavesSolvent extraction—GC-MSNo resolvable identifier
P-coumaric acidLive plantsSolvent extraction—UV/VIS spectroscopy (photometry)No resolvable identifier
SaponinsLive plantsSolvent extraction—Phytochemical screeningNo resolvable identifier
TanninsLive plantsSolvent extraction—Phytochemical screeningNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
ReproductiveUterusLive plantsSolvent extractionRat (as animal)Reproduction toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Mammen, D., Daniel, M., Sane, R. T. Phytochemical investigation of water soluble phytoconstituents of Leptadenia reticulata (Retz.) Wight & Arn. International journal of research in pharmaceutical sciences, 2010, vol. 1, no. 4, p. 486-489.
  2. Rajeswari, J., Rani, S. Gc-Ms analysis of whole plant of Leptadenia Reticulata. International journal of pharmtech research, 2014, vol. 6, no. 7, p. 2043-2050.
  3. Rajeswari, J., Rani, S. Anti-fertility efficacy of isolated compounds from Leptadenia reticulata and Lawsonia inermis. International journal of pharma and bio sciences, 2017, vol. 8, no. 1, p. 291-298.
  4. Mammen, D., Daniel, M., Sane, R.T. Pharmacognostic and phytochemical studies on Leptadenia reticulata (Retz.) wight & arn. and Ichnocarpus frutescens R. Br. For identification of distinguishing biomarkers. Pharmacognosy journal, 2011, vol. 2, no. 18, p. 7-12. DOI
  5. SRIVASTAV, S., DEEPAK, D., KHARE, A. 3 NOVEL PREGNANE GLYCOSIDES FROM LEPTADENIA-RETICULATA WIGHT AND ARN. Tetrahedron, 1994, vol. 50, no. 3, p. 789-798. DOI
  6. Rajeswari, J., Rani, S. Isolation and structural revelation of flavonoid constituents from Leptadenia reticulata Linn. Der pharma chemica, 2016, vol. 8, no. 13, p. 70-76.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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