Botanical species · safety record

Levisticum officinale

The EFSA Compendium of Botanicals holds 27 constituent measurements for Levisticum officinale. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Levisticum officinale W.J.D.Koch

27Constituent measurements

0Safety records

9Cited sources

9Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 9 licensed products naming Levisticum officinale as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Plante entière
Root
Whole plant
Whole plant(s)

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Coumarins	Roots and other underground parts	Solvent extraction	—	LC-MS	Resolve DOI
Furanocoumarins	Roots and other underground parts	Solvent extraction	—	LC-MS	Resolve DOI
Furanocoumarins	Leaves	Solvent extraction	≥ 12 Microgram/millilitre	—	Resolve DOI
Furanocoumarins	Leaves	Solvent extraction	≤ 145 Microgram/millilitre	—	Resolve DOI
Bergapten	Leaves	—	—	HPLC with standard detection methods	No resolvable identifier
Falcarindiol	Roots and other underground parts	Solvent extraction	≥ 0.14 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Falcarindiol	Roots and other underground parts	Solvent extraction	≤ 0.2 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Gallic acid	Aerial part of plants	Solvent extraction	34.13 Milligram/100 gram	HPLC-DAD	No resolvable identifier
Harman	Unspecified	—	≥ 0.11 Microgram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Harman	Unspecified	—	≤ 0.09 Microgram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Harman	Unspecified	—	≤ 0.17 Microgram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Ligustilide	Leaves	Essential oil	17 Percent	Distillation-titrimetry (modified Monier-William method)	No resolvable identifier
Ligustilide	Roots and other underground parts	Essential oil	≥ 9.4 Percent	Distillation-titrimetry (modified Monier-William method)	No resolvable identifier
Ligustilide	Roots and other underground parts	Essential oil	≤ 70.9 Percent	Distillation-titrimetry (modified Monier-William method)	No resolvable identifier
Ligustilide	Roots and other underground parts	Solvent extraction	—	LC-MS	No resolvable identifier
Methoxsalen	Leaves	—	—	HPLC with standard detection methods	No resolvable identifier
Myrcene	Live plants	—	≥ 9.5 Percent	GC-MS/MS	No resolvable identifier
Myrcene	Live plants	—	≤ 23.9 Percent	GC-MS/MS	No resolvable identifier
Norharmane	Unspecified	—	≥ 0.16 Microgram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Norharmane	Unspecified	—	≤ 0.12 Microgram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
P-coumaric acid	Live plants	—	—	HPLC-DAD	No resolvable identifier
Phenylacetaldehyde	Roots and other underground parts	Essential oil	≤ 17.2 Percent	Distillation-titrimetry (modified Monier-William method)	No resolvable identifier
Phthalides	Leaves	Essential oil	≤ 12.2 Percent	Distillation-titrimetry (modified Monier-William method)	No resolvable identifier
Phthalides	Roots and other underground parts	Essential oil	≥ 0.8 Percent	Distillation-titrimetry (modified Monier-William method)	No resolvable identifier
Phthalides	Roots and other underground parts	Essential oil	≤ 28.6 Percent	Distillation-titrimetry (modified Monier-William method)	No resolvable identifier
Phthalides	Leaves	Essential oil	≥ 2 Percent	Distillation-titrimetry (modified Monier-William method)	No resolvable identifier
Psoralen	Leaves	—	—	HPLC with standard detection methods	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

ZOBEL, AM., BROWN, SA. DERMATITIS-INDUCING PSORALENS ON THE SURFACES OF 7 MEDICINAL PLANT-SPECIES . Journal of toxicology-cutaneous and ocular toxicology, 1991, vol. 10, no. 3, p. 223-231.
Paszkiewicz, Monika., Orlita, Aleksandra., Dziabas, Alicja., Golebiowski, Marek., Lojkowska, Ewa., Szafranek, Janusz., Malinski, Edmund., Stepnowski, Piotr. Simplex optimized LC analysis of plant coumarins and furanocoumarins. Chromatographia, 2008, vol. 67, no. 7-8, p. 653-657. DOI
Ojala, T., Vuorela, P., Kiviranta, J., Vuorela, H., Hiltunen, R. A bioassay using Artemia salina for detecting phototoxicity of plant coumarins . Planta medica, 1999, vol. 65, no. 8, p. 715-718. DOI
Raal, Ain., Arak, Elmar., Orav, Anne., Kailas, Tiiu., Mueuerisepp, Mati. Composition of the essential oil of Levisticum officinale WDJ Koch from some European countries . Journal of essential oil research, 2008, vol. 20, no. 4, p. 318-322.
Zschocke, S., Liu, JH., Stuppner, H., Bauer, R. Comparative study of roots of Angelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography mass spectrometry. PHYTOCHEMICAL ANALYSIS, 1998, vol. 9, no. 6, p. 283-290.
Najda, Agnieszka., Wolski, Tadeusz., Dyduch, Jan., Baj, Tomasz. Determination of quantitative composition of poliphenolic compounds occur in anatomically different parts of Levisticum officinale Koch. Electronic journal of polish agricultural universities, 2003, vol. 6, no. 1, p. No pp given.
Dobrinas, Simona., Stanciu, Gabriela., Lupsor, Simona. TOTAL PHENOLIC CONTENT AND HPLC CHARACTERIZATION OF SOME CULINARY HERBS. Journal of science and arts, 2017, no. 2, p. 321-330.
Wojtowicz, Elzbieta., Zawirska-Wojtasiak, Renata., Przygonski, Krzysztof., Mildner-Szkudlarz, Sylwia. Bioactive beta-carbolines norharman and harman in traditional and novel raw materials for chicory coffee. Food chemistry, 2015, vol. 175, p. 280-283.
Catunescu, Giorgiana M., Socaci, Sonia Ancuta., Rotar, Ioan., Vidican, Roxana., Bunghez, Florina., Tofana, Maria., Plesa, Anca., Muntean, Mircea. Volatile Profile of Minimally Processed Herbs during Cold Storage. Romanian biotechnological letters, 2016, vol. 21, no. 5, p. 11923-11931.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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