Botanical species · safety record

Ligusticum porteri

The EFSA Compendium of Botanicals holds 12 constituent measurements and 1 adverse-effect record for Ligusticum porteri. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Ligusticum porteri J.M.Coult. & Rose

12Constituent measurements

1Safety records

5Cited sources

20Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 20 licensed products naming Ligusticum porteri as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA

Source material stated

Root

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
3-butylidenephthalide	Roots and other underground parts	Essential oil	24.41 Percent	GC-MS	Resolve DOI
3-butylidenephthalide	Roots and other underground parts	Solvent extraction	—	HPLC-UV	Resolve DOI
Alkaloids	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	Resolve DOI
Ligustilide	Roots and other underground parts	Solvent extraction	—	HPLC-UV	Resolve DOI
Myristicin	Roots and other underground parts	Solvent extraction	—	HPLC-UV	Resolve DOI
Tannins	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tokinolide b	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Z-ligustilide	Roots and other underground parts	Solvent extraction	≥ 5.4 Percent	GC-MS	Resolve DOI
Z-ligustilide	Roots and other underground parts	Solvent extraction	≤ 22.6 Percent	GC-MS	Resolve DOI
Z-ligustilide	Roots and other underground parts	Essential oil	20.2 Percent	GC-MS	Resolve DOI
Falcarindiol	Roots and other underground parts	Solvent extraction	—	GC-MS	No resolvable identifier
Phenylpropanoids	Roots and other underground parts	Solvent extraction	—	GC-MS	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Uterus	—	—	House mouse (as animal)	Other	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Rivero, Isabel., Juarez, Krutzkaya., Zuluaga, Magda., Bye, Robert., Mata, Rachel. Quantitative HPLC Method for Determining Two of the Major Active Phthalides from Ligusticum porteri Roots. JOURNAL OF AOAC INTERNATIONAL, 2012, vol. 95, no. 1, p. 84-91. DOI
Brindis, Fernando., Rodriguez, Rogelio., Bye, Robert., Gonzalez-Andrade, Martin., Mata, Rachel. (Z)-3-Butylidenephthalide from Ligusticum porteri, an alpha-Glucosidase Inhibitor. JOURNAL OF NATURAL PRODUCTS, 2011, vol. 74, no. 3, p. 314-320. DOI
Castaneda Sortibran, America., Ordaz Tellez, Maria Guadalupe., Ocotero, Veronica Munoz., Antonio Carballo-Ontiveros, Marco., Garcia, Angelica Mendez., Jimenez Valdes, Rocio Jimena., Romero Gutierrez, Elizabeth., Rodriguez-Arnaiz, Rosario. Chronic Toxicity, Genotoxic Assay, and Phytochemical Analysis of Four Traditional Medicinal Plants. JOURNAL OF MEDICINAL FOOD, 2011, vol. 14, no. 9, p. 1018-1022. DOI
Zschocke, S., Liu, JH., Stuppner, H., Bauer, R. Comparative study of roots of Angelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography mass spectrometry. PHYTOCHEMICAL ANALYSIS, 1998, vol. 9, no. 6, p. 283-290.
Leon, Alejandra., Antonio Cogordan, J., Sterner, Olov., Delgado, Guillermo. Enantiomeric Derivatives of Tokinolide B: Absolute Configuration and Biological Properties. JOURNAL OF NATURAL PRODUCTS, 2012, vol. 75, no. 5, p. 859-864. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature