Botanical species · safety record

Liriodendron tulipifera

The EFSA Compendium of Botanicals holds 11 constituent measurements for Liriodendron tulipifera. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Liriodendron tulipifera L.

11Constituent measurements

0Safety records

8Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Lignans	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Lipiferolide	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Tannins	Leaves	Solvent extraction	—	—	Resolve DOI
Aporphine alkaloids	Wood	—	—	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Aporphine alkaloids	Wood	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Costunolide	Roots and other underground parts	Solvent extraction	—	Chromatographic tests	No resolvable identifier
Isoquinoline alkaloids	Wood	—	—	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Lignans	Wood	—	—	—	No resolvable identifier
Lignans	Leaves	Solvent extraction	—	HPLC with standard detection methods	No resolvable identifier
Lirinine	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Syringaresinol	Leaves	Solvent extraction	—	HPLC with standard detection methods	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Jeong, Eun Ju., Kim, Na-Hyun., Heo, Jeong-Doo., Lee, Ki Yong., Rho, Jung-Rae., Kim, Young Choong., Sung, Sang Hyun. Antifibrotic Compounds from Liriodendron tulipifera Attenuating HSC-T6 Proliferation and TNF-alpha Production in RAW264.7 Cells. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2015, vol. 38, no. 2, p. 228-234.
Berenbaum, M.R. Effects of tannins on growth and digestion in two species of papilionids. Entomologia Experimentalis et Applicata, 1983, vol. 34, no. 3, p. 245-250. DOI
Doskotch, Raymond W., El-Feraly, Farouk S. Antitumor agents. II. Tulipinolide, a new germacranolide sesquiterpene, and costunolide. Two cytotoxic substances from Liriodendron tulipifera L. Journal of pharmaceutical sciences, 1969, p. 877-880.
Yang, Dong-Ting., Lin, Sen-Sen., Chen, Jin-Hui., Yuan, Sheng-Tao., Shi, Ji-Sen., Wang, Jun-Song., Jia, Ai-Qun. (+)- and (-)-liriodenol, a pair of novel enantiomeric lignans from Liriodendron hybrid. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, vol. 25, no. 9, p. 1976-1978. DOI
Moon, Mi Kyeong., Oh, Hyun Mi., Kwon, Byoung-Mog., Baek, Nam-In., Kim, Sung-Hoon., Kim, Ju Sin., Kim, Dae Keun. Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated from Liriodendron tulipifera. ARCHIVES OF PHARMACAL RESEARCH, 2007, vol. 30, no. 3, p. 299-302. DOI
Chen, Chen-Loung., Chang, Hou-Min., Cowling, Ellis B. The chemistry of Liriodendron tulipifera L. Part I. Aporphine alkaloids and lignans in heartwood of Liriodendron tulipifera. Phytochemistry (elsevier), 1976, p. 547-550.
Ziyaev, R., Ikramov, K., Kadyrov, Kh. A., Abdusamatov, A. Alkaloids of Liriodendron tulipifera. Khimiya Prirodnykh Soedinenii, 1991, p. 587-588.
Hufford, Charles D. Four new N-acetylnoraporphine alkaloids from Liriodendron tulipifera. Phytochemistry (Elsevier), 1976, p. 1169-1171.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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