Botanical species · safety record

Lithospermum officinale

The EFSA Compendium of Botanicals holds 5 constituent measurements for Lithospermum officinale. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Lithospermum officinale L.

5Constituent measurements

0Safety records

4Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Acetyllithosenine	Aerial part of plants	Solvent extraction	0.031 Milligram/gram	Gaschromatography (GC)	Resolve DOI
Pyrrolizidine alkaloids	Aerial part of plants	Solvent extraction	0.047 Milligram/gram	Gaschromatography (GC)	Resolve DOI
Pyrrolizidine alkaloids	—	—	—	—	Resolve DOI
Shikonin	Shoot	Solvent extraction	0.079 Milligram/gram	Capillary (Zone) Electrophoresis (CE or CZE)	Resolve DOI
[rs]-({3,3-dimethyl-5-[(methylsulfonyl)oxy]-2,3-dihydro-1-benzofuran-2-yl}oxy)acetic acid	Roots and other underground parts	—	—	—	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Wagner, Hildebert., Hoerhammer, Ludwig., Frank, U. Components of drug plants with hormone-like and antihormone-like activities. III. Lithospermic acid, the antihormonally active principle of Lycopus europaeus and Symphytum officinale. Arzneimittel-forschung, 1970, vol. 20, no. 5, p. 705-13.
Dresler, Slawomir., Szymczak, Grazyna., Wojcik, Malgorzata. Comparison of some secondary metabolite content in the seventeen species of the Boraginaceae family. . Pharmaceutical biology, 2017, vol. 55, no. 1, p. 691-695. DOI
KRENN, L., WIEDENFELD, H., ROEDER, E. PYRROLIZIDINE ALKALOIDS FROM LITHOSPERMUM-OFFICINALE. Phytochemistry, 1994, vol. 37, no. 1, p. 275-277. DOI
Roeder, E., Wiedenfeld, H. Plants containing pyrrolizidine alkaloids used in the Traditional Indian Medicine - including Ayurveda. PHARMAZIE, 2013, vol. 68, no. 2, p. 83-92. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature