Botanical species · safety record

Litsea cubeba

The EFSA Compendium of Botanicals holds 19 constituent measurements for Litsea cubeba. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Litsea cubeba (Lour.) Pers.

19Constituent measurements

0Safety records

7Cited sources

22Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 22 licensed products naming Litsea cubeba as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Fruit
Root
Root and Rhizome
Stem(s)

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
(+)-pulegone	Stem / stalk	Essential oil	1.4 Percent	GC-MS	Resolve DOI
Aporphine alkaloids	Unspecified	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Benzoquinones	Stem / stalk	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Camphor	Roots and other underground parts	Essential oil	2.1 Percent	GC-MS	Resolve DOI
Dopamine	Stem / stalk	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Isoquinoline alkaloids	Leaves	Solvent extraction	—	Element spectroscopy	Resolve DOI
Myrcene	Stem / stalk	Essential oil	3.3 Percent	GC-MS	Resolve DOI
Myrcene	Roots and other underground parts	Essential oil	2.4 Percent	GC-MS	Resolve DOI
Myrcene	Leaves	Essential oil	2 Percent	GC-MS	Resolve DOI
Myrcene	Fruit unspecified	Essential oil	2 Percent	GC-MS	Resolve DOI
Naphthalene derivatives	Stem / stalk	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Tyramine	Stem / stalk	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
1,8-cineole	Leaves	Essential oil	≤ 51.7 Percent	GC-MS	No resolvable identifier
1,8-cineole	Leaves	Essential oil	≥ 0.2 Percent	GC-MS	No resolvable identifier
Camphor	Roots and other underground parts	Essential oil	6.33 Percent	GC-MS	No resolvable identifier
Isoquinoline alkaloids	Stem / stalk	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Myrcene	Leaves	Essential oil	≥ 1.6 Percent	GC-MS	No resolvable identifier
Myrcene	Leaves	Essential oil	≤ 2 Percent	GC-MS	No resolvable identifier
Naphthalene	Roots and other underground parts	Essential oil	12.64 Percent	GC-MS	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Sun, Changlei., Li, Jia., Wang, Daijie., Yu, Jinqian., Wang, Xiao., Huang, Luqi. Preparative separation of alkaloids from Litsea cubeba using combined applications of pH-zone-refining and high-speed counter-current chromatography . Rsc advances, 2015, vol. 5, no. 92, p. 75831-75837. DOI
Chen, Z.-J., Bi, H.-P., Fan, C.-J., Bao, C.-Y. Chemical constituents from the branch of Litsea cubeba (Lour.) Pers.. Chemistry and industry of forest products, 2013, vol. 33, no. 4, p. 133-136. DOI
Fu, Shuiyu., Huang, Aijin., Liu, Huwei., Sun, Yiliang., Wu, Qiang., Xia, Yuyu. Studies of the fragrance volatile and essential oil components of Litsea cubeba root. Beijing daxue xuebao, ziran kexueban, 1992, vol. 28, no. 4, p. 460-7.
Son, Le C., Dai, Do N., Thang, Tran D., Huyen, Duong D., Ogunwande, Isiaka A. Analysis of the Essential Oils from Five Vietnamese Litsea Species (Lauraceae) . Journal of essential oil bearing plants, 2014, vol. 17, no. 5, p. 960-971. DOI
Bighelli, A., Muselli, A., Casanova, J., Tam, NT., Van Anh, V., Bessiere, JM. Chemical variability of Litsea cubeba leaf oil from Vietnam. Journal of essential oil research, 2005, vol. 17, no. 1, p. 86-88.
LEE, SS., CHEN, CK., CHEN, IS., LIU, KCS. ADDITIONAL ISOQUINOLINE ALKALOIDS FROM LITSEA-CUBEBA. Journal of the chinese chemical society, 1992, vol. 39, no. 5, p. 453-455.
Tang, Bin., Tu, Hua., Long, Han-An., Du, Jun., Guo, Jian-Min., Liu, Hong-Jin., Hu, Xin., Yang, Li., Du, Xi. A new N-methoxyl-carbonyl benzylisoquinoline from Litsea cubeba. Journal of asian natural products research, 2017, vol. 19, no. 9, p. 941-945. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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