Botanical species · safety record

Lobelia inflata

The EFSA Compendium of Botanicals holds 12 constituent measurements and 1 adverse-effect record for Lobelia inflata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Lobelia inflata L.

12Constituent measurements

1Safety records

4Cited sources

131Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 131 licensed products naming Lobelia inflata as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Fresh

Source material stated

Aerial parts
Dried aerial part(s)
Fresh above ground parts
Fruiting body
Fruiting body herb top
Grass(es)
Herb
Herb extract

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Lobeline	Roots and other underground parts	Solvent extraction	≤ 8.88 Milligram	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Lobeline	Live plants	Solvent extraction	≤ 25.04 Microgram	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Lobeline	Live plants	Solvent extraction	≥ 21.48 Microgram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Lobeline	Roots and other underground parts	Solvent extraction	≥ 5.08 Milligram	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Lobeline	Live plants	—	—	Unspecified	Resolve DOI
Lobeline	Live plants	Solvent extraction	≥ 21.48 Microgram	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Lobeline	Live plants	Solvent extraction	≤ 25.04 Microgram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Piperidine alkaloids	Roots and other underground parts	Solvent extraction	≥ 0.29 Milligram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Piperidine alkaloids	Shoot	Solvent extraction	—	HPLC-MS/MS	Resolve DOI
Piperidine alkaloids	Live plants	Solvent extraction	≥ 0.62 Milligram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Piperidine alkaloids	Live plants	Solvent extraction	≤ 0.66 Milligram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Piperidine alkaloids	Roots and other underground parts	Solvent extraction	≤ 0.31 Milligram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Systemic	Brain	Live plants	Drying (dehydration)	Rabbit (as animal)	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Banyai, Peter., Vojnich, Viktor Jozsef., Mathe, Akos., Kursinszki, Laszlo., Szoke, Eva. Enhancement of the anti-addictive lobeline and related alkaloid production of in vitro micropropagated Lobelia inflata L. . In vitro cellular & developmental biology-plant, 2014, vol. 50, no. 6, p. 760-765. DOI
Kursinszki, Laszlo., Szoke, Eva. HPLC-ESI-MS/MS of brain neurotransmitter modulator lobeline and related piperidine alkaloids in Lobelia inflata L . Journal of mass spectrometry, 2015, vol. 50, no. 5, p. 727-733. DOI
Johnson, H. Case of suspected poisoning by lobelia inflata: With the appearances after death. British medical journal, 1858, vol. s4-1, no. 77, p. 493-495. DOI
da Costa E Silva, Liana Dantas., Rodrigues, Laise Carla Lima Verde., Dos Santos, Viviane Ramos., da Costa Allgayer, Mariangela., de Barros Falcao Ferraz, Alexandre., Rolla, Helena Campos., Pereira, Patricia., Picada, Jaqueline Nascimento. Evaluation of mutagenic and genotoxic activities of lobeline and its modulation on genomic instability induced by ethanol. . Life sciences, 2014, vol. 103, no. 2, p. 73-8. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature