Botanical species · safety record

Lolium temulentum

The EFSA Compendium of Botanicals holds 2 constituent measurements and 4 adverse-effect records for Lolium temulentum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Lolium temulentum L.

2Constituent measurements
4Safety records
4Cited sources
4Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 4 licensed products naming Lolium temulentum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Ripe spikelets

What the records describe

Constituents measured

  • Pyrrolizidine alkaloids2

Plant parts

  • Seed3
  • Aerial part of plants1

Preparations

  • Solvent extraction5

Effect types

  • Systemic2
  • Neurotoxicity1
  • Pulmonary and cardiac1

Target tissues

  • Heart1
  • Neurologic1
  • Neurologic: central nervous system1
  • Respiratory1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Pyrrolizidine alkaloidsSeedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
Pyrrolizidine alkaloidsAerial part of plantsSolvent extractionUnspecifiedResolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
NeurotoxicityNeurologic: central nervous systemSeedSolvent extractionRat (as animal)Acute toxicityResolve DOI
Pulmonary and cardiacRespiratorySeedCattle (as animal)Not reportedResolve DOI
SystemicHeartSolvent extractionRabbit (as animal)OtherResolve DOI
SystemicNeurologicSolvent extractionHuman (as organism)Case reportResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Hammouda, F.M., Rizk, A.M., El-Missiry, M.M., Ghaleb, H.A., Madkour, M.K., Pohland, A.E., Wood, G. Poisonous plants contaminating edible ones and toxic substances in plant foods IV. Phytochemistry and toxicity of lolium temulentum. Pharmaceutical biology, 1988, vol. 26, no. 4, p. 240-245. DOI
  2. Al-Qura'n, S. Ethnobotanical survey of folk toxic plants in southern part of Jordan. Toxicon, 2005, vol. 46, no. 2, p. 119-129. DOI
  3. Antze, P. Lolium temulentum in pharmakognostischer, chemischer, physiologischer und toxikologischer Hinsicht. Archiv f�r experimentelle pathologie und pharmakologie, 1891, vol. 28, no. 1-2, p. 126-144. DOI
  4. Roeder, E., Wiedenfeld, H. Plants containing pyrrolizidine alkaloids used in the Traditional Indian Medicine - including Ayurveda. PHARMAZIE, 2013, vol. 68, no. 2, p. 83-92. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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