Botanical species · safety record
Lolium temulentum
The EFSA Compendium of Botanicals holds 2 constituent measurements and 4 adverse-effect records for Lolium temulentum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Lolium temulentum L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 4 licensed products naming Lolium temulentum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- Pyrrolizidine alkaloids2
Plant parts
- Seed3
- Aerial part of plants1
Preparations
- Solvent extraction5
Effect types
- Systemic2
- Neurotoxicity1
- Pulmonary and cardiac1
Target tissues
- Heart1
- Neurologic1
- Neurologic: central nervous system1
- Respiratory1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Pyrrolizidine alkaloids | Seed | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Pyrrolizidine alkaloids | Aerial part of plants | Solvent extraction | — | Unspecified | Resolve DOI |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Neurotoxicity | Neurologic: central nervous system | Seed | Solvent extraction | Rat (as animal) | Acute toxicity | Resolve DOI |
| Pulmonary and cardiac | Respiratory | Seed | — | Cattle (as animal) | Not reported | Resolve DOI |
| Systemic | Heart | — | Solvent extraction | Rabbit (as animal) | Other | Resolve DOI |
| Systemic | Neurologic | — | Solvent extraction | Human (as organism) | Case report | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Hammouda, F.M., Rizk, A.M., El-Missiry, M.M., Ghaleb, H.A., Madkour, M.K., Pohland, A.E., Wood, G. Poisonous plants contaminating edible ones and toxic substances in plant foods IV. Phytochemistry and toxicity of lolium temulentum. Pharmaceutical biology, 1988, vol. 26, no. 4, p. 240-245. DOI
- Al-Qura'n, S. Ethnobotanical survey of folk toxic plants in southern part of Jordan. Toxicon, 2005, vol. 46, no. 2, p. 119-129. DOI
- Antze, P. Lolium temulentum in pharmakognostischer, chemischer, physiologischer und toxikologischer Hinsicht. Archiv f�r experimentelle pathologie und pharmakologie, 1891, vol. 28, no. 1-2, p. 126-144. DOI
- Roeder, E., Wiedenfeld, H. Plants containing pyrrolizidine alkaloids used in the Traditional Indian Medicine - including Ayurveda. PHARMAZIE, 2013, vol. 68, no. 2, p. 83-92. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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