Botanical species · safety record

Magnolia kobus

The EFSA Compendium of Botanicals holds 43 constituent measurements for Magnolia kobus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Magnolia kobus DC.

43Constituent measurements

0Safety records

10Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
(+)-epieudesmine	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Alkaloids	Leaves	Solvent extraction	≥ 0.019 Percent	Unspecified	Resolve DOI
Alkaloids	Leaves	Solvent extraction	≤ 0.31 Percent	Unspecified	Resolve DOI
Anonaine	Leaves	Solvent extraction	—	Unspecified	Resolve DOI
Asimilobine	Leaves	Solvent extraction	—	Unspecified	Resolve DOI
Costunolide	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Kobusin	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Lignans	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Liriodenine	Leaves	Solvent extraction	—	Unspecified	Resolve DOI
Liriodenine	Wood	Solvent extraction	≥ 0.12 Percent	Unspecified	Resolve DOI
Liriodenine	Wood	Solvent extraction	≤ 0.18 Percent	Unspecified	Resolve DOI
Magnoflorine	Stem / stalk	Solvent extraction	0.044 Percent	HPLC-UV	Resolve DOI
Parthenolide	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Parthenolide	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Pinoresinol	Unspecified	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Sesquiterpene lactones	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Sesquiterpene lactones	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Syringaresinol	Leaves	Solvent extraction	—	Unspecified	Resolve DOI
(+)-epieudesmine	Flower	Solvent extraction	≤ 0.0127 Percent	HPLC-UV	No resolvable identifier
(+)-epieudesmine	Flower	Solvent extraction	≥ 0.0024 Percent	HPLC-UV	No resolvable identifier
1,8-cineole	Aerial part of plants	Essential oil	—	—	No resolvable identifier
Benzofurans	Flower	Solvent extraction	≥ 0.1167 Percent	HPLC-UV	No resolvable identifier
Benzofurans	Flower	Solvent extraction	≤ 1.0263 Percent	HPLC-UV	No resolvable identifier
Epi-magnolin a	Flower	Solvent extraction	≥ 0.0014 Percent	HPLC-UV	No resolvable identifier
Epi-magnolin a	Flower	Solvent extraction	≤ 0.0016 Percent	HPLC-UV	No resolvable identifier
Estragole	Aerial part of plants	Essential oil	—	—	No resolvable identifier
Eugenol	Aerial part of plants	Essential oil	—	—	No resolvable identifier
Isoquinoline alkaloids	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Kobusin	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Kobusin	Flower	Solvent extraction	≥ 0.0913 Percent	HPLC-UV	No resolvable identifier
Kobusin	Flower	Solvent extraction	≤ 0.1338 Percent	HPLC-UV	No resolvable identifier
Lignans	Flower	Solvent extraction	≥ 3e-04 Percent	HPLC-UV	No resolvable identifier
Lignans	Flower	Solvent extraction	≤ 4e-04 Percent	HPLC-UV	No resolvable identifier
Lignans	Flower	Solvent extraction	≥ 0.0124 Percent	HPLC-UV	No resolvable identifier
Lignans	Flower	Solvent extraction	≤ 0.0267 Percent	HPLC-UV	No resolvable identifier
Magnocurarine	Leaves	Solvent extraction	—	Chromatographic tests	No resolvable identifier
Magnoline	Flower	Solvent extraction	≤ 0.0316 Percent	HPLC-UV	No resolvable identifier
Magnoline	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Magnoline	Flower	Solvent extraction	≥ 0.0091 Percent	HPLC-UV	No resolvable identifier
Salicifoline	Stem / stalk	Raw, no heat treatment	—	Microscopic detection	No resolvable identifier

40 of 43 records are shown, ordered so that records carrying a resolvable reference come first.

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Fang, Zhe., Shen, Chang Min., Moon, Dong Cheul., Son, Kun Ho., Son, Jong Keun., Woo, Mi Hee. Quantitative and pattern recognition analyses for the quality evaluation of Magnoliae Flos by HPLC. Bulletin of the korean chemical society, 2010, vol. 31, no. 11, p. 3371-3381.
Fujita, Yasuji. Constituents of essential oils from Magnolia kobus and M. salicifolia. J. japan. botan, 1955, vol. 30, p. 188-90.
Ziyaev, R., Shtonda, NI., Sturua, MD., Abdusamatov, A., Tsakadze, DM. Alkaloids of some Magnolia species. Chemistry of natural compounds, 1999, vol. 35, no. 3, p. 366-367. DOI
Park, Hee Wook., Lee, Jae Hyeok., Choi, Sang-Un., Baek, Nam-In., Kim, Sung-Hoon., Yang, Jae Heon., Kim, Dae Keun. Cytotoxic Germacranolide Sesquiterpenes from the Bark of Magnolia kobus. Archives of pharmacal research, 2010, vol. 33, no. 1, p. 71-74. DOI
Lee, Hak-Ju., Seo, Seon-Mi., Lee, Oh-Kyu., Jo, Hyun-Jin., Kang, Ha-Young., Choi, Don-Ha., Paik, Ki-Hyon., Khan, Merajuddin. Lignans from the Bark of Magnolia kobus. Helvetica chimica acta, 2008, vol. 91, no. 12, p. 2361-2366.
Takahashi, H., Yoshioka, S., Kawano, S., Azuma, H., Fukuyama, Y. Lignans and sesquiterpenes from Magnolia praecocissima. Chemical & pharmaceutical bulletin, 2002, vol. 50, no. 4, p. 541-543. DOI
FURMANOWA, M., JOZEFOWICZ, J. ALKALOIDS AS TAXONOMIC MARKERS IN SOME SPECIES OF MAGNOLIA L AND LIRIODENDRON L . Acta societatis botanicorum poloniae, 1980, vol. 49, no. 4, p. 527-535.
SLAVIK, J., SLAVIKOVA, L. QUATERNARY ISOQUINOLINE ALKALOIDS AND SOME DITERPENOID ALKALOIDS IN PLANTS OF THE CZECH-REPUBLIC . Collection of czechoslovak chemical communications, 1995, vol. 60, no. 6, p. 1034-1041. DOI
Okumura Wakaba., Aoki Dan., Matsushita Yasuyuki., Yoshida Masato., Fukushima Kazuhiko. Distribution of salicifoline in freeze-fixed stems of Magnolia kobus as observed by cryo-TOF-SIMS. Scientific reports, 2017, vol. 7, no. 1, p. 5939.
Miyauchi, T., Ozawa, S. Formation of (+)-eudesmin in Magnolia kobus DC. var. Borealis sarg.. Phytochemistry, 1998, vol. 47, no. 4, p. 665-670. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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