Botanical species · safety record

Mallotus philippensis

The EFSA Compendium of Botanicals holds 12 constituent measurements and 3 adverse-effect records for Mallotus philippensis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Mallotus philippensis (Lam.) Müll.Arg.

12Constituent measurements

3Safety records

8Cited sources

2Licensed products (Canada)

Also recorded as

Mallotus philippinensis var. reticulatus (Dunn) F.P. Metcalf

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 2 licensed products naming Mallotus philippensis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Glandular hairs of fruit
Hairs and glands

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Bergenin	Bark	Solvent extraction	11 Percent	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Coumarins	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Ellagitannins (hydrolysable tannins)	Unspecified	—	—	Element spectroscopy	Resolve DOI
Rottlerin	Seed	Solvent extraction	—	Unspecified	Resolve DOI
Rottlerin	Fruit unspecified	Solvent extraction	—	Unspecified	Resolve DOI
Saponins	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Fruit peel	Solvent extraction	—	Phytochemical screening	Resolve DOI
Alkaloids	Leaves	—	—	Microscopic detection	No resolvable identifier
Bergenin	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectroscopy	No resolvable identifier
Calcium oxalate	Leaves	—	—	Microscopic detection	No resolvable identifier
Tannins	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Reproductive	—	Seed	Solvent extraction	Rat (as animal)	Reproduction toxicity	Resolve DOI
Reproductive	—	Seed	Solvent extraction	Rat (as animal)	Reproduction toxicity	Resolve DOI
Not stated	Digestive	Bark	Solvent extraction	—	In vitro	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Vijaya Kumar, T., Tiwari, A.K., Robinson, A., Suresh Babu, K., Sateesh Chandra Kumar, R., Anand Kumar, D., Zehra, A., Madhusudna Rao, J. Synthesis and antiglycation potentials of bergenin derivatives. Bioorganic and medicinal chemistry letters, 2011, vol. 21, no. 16, p. 4928-4931. DOI
Hewageegana, H. G. S. P., Arawwawala, L. D. A. M., Tissera, M. H. A., Ariyawansa, H. A. S., Dhammaratana, I. A comparison of the physico-chemical and phytochemical parameters of glands/hairs of fruits and leaves of Mallotus philippensis (Lam.) Muell. Arg. grown in Sri Lanka . Journal of the national science foundation of sri lanka, 2014, vol. 42, no. 3, p. 265-269. DOI
Thakur, SC., Thakur, SS., Chaube, SK., Singh, SP. An etheral extract of Kamala (Mallotus philippinensis (Moll.Arg) Lam.) seed induce adverse effects on reproductive parameters of female rats . Reproductive toxicology, 2005, vol. 20, no. 1, p. 149-156. DOI
Nguyen Thi Mai., Nguyen Xuan Cuong., Nguyen Phuong Thao., Nguyen Hoai Nam., Nguyen Huu Khoi., Chau Van Minh., Vander Heyden, Yvan., Ngo Thi Thuan., Nguyen Van Tuyen., Quetin-Leclercq, Joelle., Phan Van Kiem. A New Lignan Dimer from Mallotus philippensis. Natural product communications, 2010, vol. 5, no. 3, p. 423-426.
Velraj, Malarkodi., Ravichandiran, V., Deepthi, R., Jayaraman, P. Pharmacognostic perspectives of Mallotus philippensis. Journal of medicinal and aromatic plant sciences, 2011, vol. 33, no. 3, p. 319-325.
Abe, I., Kashiwagi, Y., Noguchi, H., Tanaka, T., Ikeshiro, Y., Kashiwada, Y. Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase . Journal of natural products, 2001, vol. 64, no. 8, p. 1010-1014. DOI
Li, Yangfeng., Yu, Biao., Wang, Renxiao. Efficient synthesis of rottlerin and its two subunits. Tetrahedron letters, 2016, vol. 57, no. 17, p. 1856-1859. DOI
SAIJO, R., NONAKA, G., NISHIOKA, I., CHEN, IS., HWANG, TH. TANNINS AND RELATED-COMPOUNDS .88. ISOLATION AND CHARACTERIZATION OF HYDROLYZABLE TANNINS FROM MALLOTUS-JAPONICUS (THUNB) MUELLER-ARG AND MALLOTUS-PHILIPPINENSIS (LAM) MUELLER-ARG . Chemical & pharmaceutical bulletin, 1989, vol. 37, no. 11, p. 2940-2947.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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