Botanical species · safety record

Mangifera indica

The EFSA Compendium of Botanicals holds 18 constituent measurements and 4 adverse-effect records for Mangifera indica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Mangifera indica L.

18Constituent measurements

4Safety records

8Cited sources

134Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 134 licensed products naming Mangifera indica as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Bark
Fruit
Fruit Powder
Fruit peel
Leaf
Mangifera indica - Fruit
Mangifera indica - fruit
Seed

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Bark	Solvent extraction	—	Phytochemical screening	Resolve DOI
Alkaloids	Fruit peel	Solvent extraction	—	Phytochemical screening	Resolve DOI
Gallic acid	Fruit unspecified	Solvent extraction	27.9 Percent	UV/VIS spectroscopy (photometry)	Resolve DOI
Gallic acid	Fruit unspecified	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Gallotannins	Fruit unspecified	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Melatonin	Fruit unspecified	Solvent extraction	699 Picogram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Saponins	Bark	Solvent extraction	—	Phytochemical screening	Resolve DOI
Saponins	Fruit peel	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannic acid	Fruit unspecified	Solvent extraction	46.6 Percent	UV/VIS spectroscopy (photometry)	Resolve DOI
Tannins	Bark	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Fruit peel	Solvent extraction	—	Phytochemical screening	Resolve DOI
Cyanogenic glycosides	Seed	Thermal treatment (heating for preservation)	≥ 19 Milligram/kilogram	Unspecified	No resolvable identifier
Cyanogenic glycosides	Seed	Thermal treatment (heating for preservation)	≤ 64 Milligram/kilogram	Unspecified	No resolvable identifier
Oxalates	Seed	Thermal treatment (heating for preservation)	≥ 10 Milligram/kilogram	—	No resolvable identifier
Oxalates	Seed	Thermal treatment (heating for preservation)	≤ 42 Milligram/kilogram	—	No resolvable identifier
Tannins	Seed	—	≥ 19 Gram/kilogram	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Tannins	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Seed	—	≤ 56.5 Gram/kilogram	Traditional analytical techniques (wet chemical tests)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Seed	—	—	In vitro	No resolvable identifier
Digestive	Digestive	Seed	Solvent extraction	—	In vitro	No resolvable identifier
Digestive	Digestive	Seed	Solvent extraction	—	In vitro	No resolvable identifier
Digestive	Digestive	Seed	—	—	In vitro	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Ravindran, V., Sivakanesan, R. The nutritive value of mango seed kernels for starting chicks. Journal of the science of food and agriculture, 1996, vol. 71, no. 2, p. 245-250.
Khan, Mohammad Ahad Ali., Islam, Mohammad Torequl. Analgesic and cytotoxic activity of Acorus calamus L., Kigelia pinnata L., Mangifera indica L. and Tabernaemontana divaricata L. . Journal of pharmacy & bioallied sciences, 2012, vol. 4, no. 2, p. 149-54. DOI
Chowdhury, S., Poddar, S.K., Zaheen, S., Noor, F.A., Ahmed, N., Haque, S., Sukul, A., Sunjida, S.B., Mazumder, M.M.U., Akbar, N. Phytochemical screening and evaluation of cytotoxic and hypoglycemic properties of Mangifera indica peels. Asian pacific journal of tropical biomedicine, 2017, vol. 7, no. 1, p. 49-52. DOI
Arogba, Sunday S. Mango (Mangifera indica) kernel: Chromatographic analysis of the Tannin, and stability study of the associated polyphenol oxidase activity . Journal of food composition and analysis, 2000, vol. 13, no. 2, p. 149-156. DOI
Sharma, Monica., Rathee, Sushila., Permender, Rathee., Naveen, Yadav. Preliminary phytochemical screening and anti diabetic activity of roots Mangifera indica Linn. Pharmacologyonline, 2010, p. 968-974.
Irondi, Emmanuel Anyachukwu., Oboh, Ganiyu., Akindahunsi, Afolabi Akintunde., Boligon, Aline Augusti., Athayde, Margareth Linde. Phenolic composition and inhibitory activity of Mangifera indica and Mucuna urens seeds extracts against key enzymes linked to the pathology and complications of type 2 diabetes . Asian pacific journal of tropical biomedicine, 2014, vol. 4, no. 11, p. 903-910.
Banerjee, Niuedita., Kim, Hyemee., Krenek, Kimberly., Talcott, Stephen T., Mertens-Talcott, Susanne U. Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: role of the PI3K/AKT pathway and associated microRNAs . Nutrition research, 2015, vol. 35, no. 8, p. 744-751. DOI
Johns, Nutjaree Pratheepawanit., Johns, Jeffrey., Porasuphatana, Supatra., Plaimee, Preeyaporn., Sae-Teaw, Manit. Dietary Intake of Melatonin from Tropical Fruit Altered Urinary Excretion of 6-Sulfatoxymelatonin in Healthy Volunteers . Journal of agricultural and food chemistry, 2013, vol. 61, no. 4, p. 913-919. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature