Botanical species · safety record

Marrubium vulgare

The EFSA Compendium of Botanicals holds 9 constituent measurements and 1 adverse-effect record for Marrubium vulgare. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Marrubium vulgare L.

9Constituent measurements

1Safety records

4Cited sources

142Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 142 licensed products naming Marrubium vulgare as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Aerial flowering part
Aerial part of flowering plant
Aerial parts
Flower
Fresh aerial part collected at flowering time
Fruit
Herb
Herb extract

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
1,8-cineole	Aerial part of plants	Essential oil	4.8 Percent	GC-MS	No resolvable identifier
Alkaloids	Live plants	Solvent extraction	—	—	No resolvable identifier
Camphor	Aerial part of plants	Essential oil	2.3 Percent	GC-MS	No resolvable identifier
Eugenol	Aerial part of plants	Essential oil	3.3 Percent	GC-MS	No resolvable identifier
Labdane diterpenes	Stem / stalk	Solvent extraction	0.5 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Labdane diterpenes	Roots and other underground parts	Solvent extraction	0.05 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Labdane diterpenes	Leaves	Solvent extraction	3 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Labdane diterpenes	Flower	Solvent extraction	≤ 3 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Labdane diterpenes	Flower	Solvent extraction	≥ 2.5 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Live plants	Solvent extraction	Rat (as animal)	In vitro	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Hamdaoui, Bochra., Wannes, Wissem Aidi., Marrakchi, Mohamed., Ben Brahim, Nadia., Marzouk, Brahim. Essential Oil Composition of Two Tunisian Horehound Species: Marrubium vulgare L. and Marrubium aschersonii Magnus. JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2013, vol. 16, no. 5, p. 608-612.
Mata, R., Cristians, S., Escand�n-Rivera, S., Ju�rez-Reyes, K., Rivero-Cruz, I. Mexican antidiabetic herbs: Valuable sources of inhibitors of alpha-glucosidases. Journal of natural products, 2013, vol. 76, no. 3, p. 468-483. DOI
Knoess, Werner., Zapp, Josef. Accumulation of furanic labdane diterpenes in Marrubium vulgare and Leonurus cardiaca. Planta Medica, 1998, vol. 64, no. 4, p. 357-361.
Aliev, R. K., Aliev, A. M. Chemical composition of Marrubium vulgare and effect of its preparations on cardiovascular system. Uchenye zapiski azerbaidzhan. gosudarst. univ. im. s. m. kirova, 1956, p. 69-75.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature