Botanical species · safety record
Melaleuca leucadendra
The EFSA Compendium of Botanicals holds 22 constituent measurements for Melaleuca leucadendra. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Melaleuca leucadendra (L.) L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Melaleuca leucadendra as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- (-)-globulol3
- 1,8-cineole3
- Eugenol3
- Methyleugenol3
- Beta-selinene2
- Methylisoeugenol2
- 1,4-naphthoquinone1
- 2,3-dimethylcolchicine1
- 3,4-dihydroxybenzoic acid1
- Ellagitannins (hydrolysable tannins)1
Plant parts
- Leaves17
- Fruit unspecified3
- Wood2
Preparations
- Essential oil15
- Solvent extraction7
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| (-)-globulol | Leaves | Essential oil | 23.06 Percent | GC-FID-MS | Resolve DOI |
| (-)-globulol | Leaves | Essential oil | ≤ 3.6 Percent | GC-MS | Resolve DOI |
| (-)-globulol | Leaves | Essential oil | ≥ 1.28 Percent | GC-MS | Resolve DOI |
| 1,4-naphthoquinone | Leaves | Solvent extraction | 10.38 Percent | GC-FID-MS | Resolve DOI |
| 1,8-cineole | Leaves | Essential oil | 28.87 Percent | GC-FID-MS | Resolve DOI |
| 1,8-cineole | Leaves | Essential oil | ≤ 60.19 Percent | GC-MS | Resolve DOI |
| 1,8-cineole | Leaves | Essential oil | ≥ 44.76 Percent | GC-MS | Resolve DOI |
| 2,3-dimethylcolchicine | Wood | Solvent extraction | 2.72 Percent | GC-MS | Resolve DOI |
| 3,4-dihydroxybenzoic acid | Fruit unspecified | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Beta-selinene | Leaves | Essential oil | ≤ 3.51 Percent | GC-MS | Resolve DOI |
| Beta-selinene | Leaves | Essential oil | ≥ 0.98 Percent | GC-MS | Resolve DOI |
| Ellagitannins (hydrolysable tannins) | Fruit unspecified | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Erucic acid | Wood | Solvent extraction | 16.95 Percent | GC-MS | Resolve DOI |
| Eugenol | Leaves | Solvent extraction | 3.36 Percent | GC-FID-MS | Resolve DOI |
| Eugenol | Leaves | Essential oil | ≤ 4.85 Percent | GC-MS | Resolve DOI |
| Eugenol | Leaves | Essential oil | ≥ 2.68 Percent | GC-MS | Resolve DOI |
| Methyleugenol | Leaves | Essential oil | ≤ 97.4 Percent | GC-MS | Resolve DOI |
| Methyleugenol | Leaves | Essential oil | ≥ 8.9 Percent | GC-MS | Resolve DOI |
| Methyleugenol | Leaves | Essential oil | 96.6 Percent | GC-FID | Resolve DOI |
| Methylisoeugenol | Leaves | Essential oil | ≤ 88.8 Percent | GC-MS | Resolve DOI |
| Methylisoeugenol | Leaves | Essential oil | ≥ 0.2 Percent | GC-MS | Resolve DOI |
| Stilbenes, stilbene derivatives | Fruit unspecified | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Fall, Rokhaya., Ngom, Saliou., Sall, Dienaba., Sembene, Mbacke., Samb, Abdoulaye. Chemical characterization of essential oil from the leaves of Callistemon viminalis (DR) and Melaleuca leucadendron (Linn.) . Asian pacific journal of tropical biomedicine, 2017, vol. 7, no. 4, p. 347-351. DOI
- Pujiarti, Rini., Ohtani, Yoshito., Ichiura, Hideaki. Physicochemical properties and chemical compositions of Melaleuca leucadendron leaf oils taken from the plantations in Java, Indonesia . Journal of wood science, 2011, vol. 57, no. 5, p. 446-451. DOI
- Brophy, J.J., Lassak, E.V. Melaleuca leucadendra L. leaf oil:Two phenylpropanoid chemotypes. Flavour and fragrance journal, 1988, vol. 3, no. 1, p. 43-46. DOI
- Silva, Cleber J., Barbosa, Luiz C. A., Maltha, Ulia R. A., Pinheiro, Antonio L., Ismail, Fyaz M. D. Comparative study of the essential oils of seven Meialeuca (Myrtaceae) species grown in Brazil. FLAVOUR AND FRAGRANCE JOURNAL, 2007, vol. 22, no. 6, p. 474-478. DOI
- Indrayani, Yuliati., Muin, Musrizal., Yoshimura, Tsuyoshi. Crude extracts of two different leaf plant species and their responses against subterranean termite Coptotermes formosanus . Nusantara bioscience, 2016, vol. 8, no. 2, p. 226-231. DOI
- Xu, Kaimeng., Feng, Jing., Zhong, Tuhua., Zheng, Zhifeng., Chen, Taian. Effects of volatile chemical components of wood species on mould growth susceptibility and termite attack resistance of wood plastic composites . International biodeterioration & biodegradation, 2015, vol. 100, p. 106-115. DOI
- Yoshida, T., Maruyama, T., Nitta, A., Okuda, T. An hydrolysable tannin and accompanying polyphenols from Melaleuca leucadendron . Phytochemistry, 1996, vol. 42, no. 4, p. 1171-1173. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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