Botanical species · safety record

Melaleuca leucadendra

The EFSA Compendium of Botanicals holds 22 constituent measurements for Melaleuca leucadendra. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Melaleuca leucadendra (L.) L.

22Constituent measurements
0Safety records
7Cited sources
1Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Melaleuca leucadendra as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Leaf

What the records describe

Constituents measured

  • (-)-globulol3
  • 1,8-cineole3
  • Eugenol3
  • Methyleugenol3
  • Beta-​selinene2
  • Methylisoeugenol2
  • 1,4-naphthoquinone1
  • 2,3-dimethylcolchicine1
  • 3,4-dihydroxybenzoic acid1
  • Ellagitannins (hydrolysable tannins)1

Plant parts

  • Leaves17
  • Fruit unspecified3
  • Wood2

Preparations

  • Essential oil15
  • Solvent extraction7

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
(-)-globulolLeavesEssential oil23.06 PercentGC-FID-MSResolve DOI
(-)-globulolLeavesEssential oil≤ 3.6 PercentGC-MSResolve DOI
(-)-globulolLeavesEssential oil≥ 1.28 PercentGC-MSResolve DOI
1,4-naphthoquinoneLeavesSolvent extraction10.38 PercentGC-FID-MSResolve DOI
1,8-cineoleLeavesEssential oil28.87 PercentGC-FID-MSResolve DOI
1,8-cineoleLeavesEssential oil≤ 60.19 PercentGC-MSResolve DOI
1,8-cineoleLeavesEssential oil≥ 44.76 PercentGC-MSResolve DOI
2,3-dimethylcolchicineWoodSolvent extraction2.72 PercentGC-MSResolve DOI
3,4-dihydroxybenzoic acidFruit unspecifiedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
Beta-​selineneLeavesEssential oil≤ 3.51 PercentGC-MSResolve DOI
Beta-​selineneLeavesEssential oil≥ 0.98 PercentGC-MSResolve DOI
Ellagitannins (hydrolysable tannins)Fruit unspecifiedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
Erucic acidWoodSolvent extraction16.95 PercentGC-MSResolve DOI
EugenolLeavesSolvent extraction3.36 PercentGC-FID-MSResolve DOI
EugenolLeavesEssential oil≤ 4.85 PercentGC-MSResolve DOI
EugenolLeavesEssential oil≥ 2.68 PercentGC-MSResolve DOI
MethyleugenolLeavesEssential oil≤ 97.4 PercentGC-MSResolve DOI
MethyleugenolLeavesEssential oil≥ 8.9 PercentGC-MSResolve DOI
MethyleugenolLeavesEssential oil96.6 PercentGC-FIDResolve DOI
MethylisoeugenolLeavesEssential oil≤ 88.8 PercentGC-MSResolve DOI
MethylisoeugenolLeavesEssential oil≥ 0.2 PercentGC-MSResolve DOI
Stilbenes, stilbene derivativesFruit unspecifiedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Fall, Rokhaya., Ngom, Saliou., Sall, Dienaba., Sembene, Mbacke., Samb, Abdoulaye. Chemical characterization of essential oil from the leaves of Callistemon viminalis (DR) and Melaleuca leucadendron (Linn.) . Asian pacific journal of tropical biomedicine, 2017, vol. 7, no. 4, p. 347-351. DOI
  2. Pujiarti, Rini., Ohtani, Yoshito., Ichiura, Hideaki. Physicochemical properties and chemical compositions of Melaleuca leucadendron leaf oils taken from the plantations in Java, Indonesia . Journal of wood science, 2011, vol. 57, no. 5, p. 446-451. DOI
  3. Brophy, J.J., Lassak, E.V. Melaleuca leucadendra L. leaf oil:Two phenylpropanoid chemotypes. Flavour and fragrance journal, 1988, vol. 3, no. 1, p. 43-46. DOI
  4. Silva, Cleber J., Barbosa, Luiz C. A., Maltha, Ulia R. A., Pinheiro, Antonio L., Ismail, Fyaz M. D. Comparative study of the essential oils of seven Meialeuca (Myrtaceae) species grown in Brazil. FLAVOUR AND FRAGRANCE JOURNAL, 2007, vol. 22, no. 6, p. 474-478. DOI
  5. Indrayani, Yuliati., Muin, Musrizal., Yoshimura, Tsuyoshi. Crude extracts of two different leaf plant species and their responses against subterranean termite Coptotermes formosanus . Nusantara bioscience, 2016, vol. 8, no. 2, p. 226-231. DOI
  6. Xu, Kaimeng., Feng, Jing., Zhong, Tuhua., Zheng, Zhifeng., Chen, Taian. Effects of volatile chemical components of wood species on mould growth susceptibility and termite attack resistance of wood plastic composites . International biodeterioration & biodegradation, 2015, vol. 100, p. 106-115. DOI
  7. Yoshida, T., Maruyama, T., Nitta, A., Okuda, T. An hydrolysable tannin and accompanying polyphenols from Melaleuca leucadendron . Phytochemistry, 1996, vol. 42, no. 4, p. 1171-1173. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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