Botanical species · safety record
Melittis melissophyllum
The EFSA Compendium of Botanicals holds 15 constituent measurements for Melittis melissophyllum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Melittis melissophyllum L.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Coumarin6
- 2-hydroxycinnamic acid2
- 3,4-dihydroxybenzoic acid2
- 4-hydroxybenzoic acid2
- P-coumaric acid2
- (-)-camphor1
Plant parts
- Aerial part of plants11
- Leaves4
Preparations
- Solvent extraction12
- Essential oil1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| (-)-camphor | Aerial part of plants | Essential oil | 3.61 Percent | GC-MS | Resolve DOI |
| 2-hydroxycinnamic acid | Aerial part of plants | Solvent extraction | ≤ 2.61 Milligram/100 gram | HPLC-DAD | Resolve DOI |
| 2-hydroxycinnamic acid | Aerial part of plants | Solvent extraction | ≥ 0.63 Milligram/100 gram | HPLC-DAD | Resolve DOI |
| 3,4-dihydroxybenzoic acid | Aerial part of plants | Solvent extraction | ≤ 8.22 Milligram/100 gram | HPLC-DAD | Resolve DOI |
| 3,4-dihydroxybenzoic acid | Aerial part of plants | Solvent extraction | ≥ 2.1 Milligram/100 gram | HPLC-DAD | Resolve DOI |
| 4-hydroxybenzoic acid | Aerial part of plants | Solvent extraction | ≤ 110.91 Milligram/100 gram | HPLC-DAD | Resolve DOI |
| 4-hydroxybenzoic acid | Aerial part of plants | Solvent extraction | ≥ 30.21 Milligram/100 gram | HPLC-DAD | Resolve DOI |
| Coumarin | Leaves | Solvent extraction | ≤ 14392 Milligram/kilogram | HPLC-DAD | Resolve DOI |
| Coumarin | Leaves | Solvent extraction | ≤ 11125 Milligram/kilogram | HPLC-DAD | Resolve DOI |
| Coumarin | Leaves | Solvent extraction | ≥ 4588 Milligram/kilogram | HPLC-DAD | Resolve DOI |
| Coumarin | Leaves | Solvent extraction | ≥ 3091 Milligram/kilogram | HPLC-DAD | Resolve DOI |
| Coumarin | Aerial part of plants | — | ≤ 38.5 Percent | GC-MS | Resolve DOI |
| Coumarin | Aerial part of plants | — | ≥ 0.2 Percent | GC-MS | Resolve DOI |
| P-coumaric acid | Aerial part of plants | Solvent extraction | ≤ 121.4 Milligram/100 gram | HPLC-DAD | Resolve DOI |
| P-coumaric acid | Aerial part of plants | Solvent extraction | ≥ 40.48 Milligram/100 gram | HPLC-DAD | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Skaltsa-Diamantidis, H., Tsitsa-Tzardi, E., Tzakou, O., Argyriadou, N. Analysis of the essential oil of Melittis melissophyllum L. Subsp. albida Guss. Journal of essential oil research, 1991, vol. 3, no. 5, p. 367-368. DOI
- Skrzypczak-Pietraszek, Ewa., Pietraszek, Jacek. Chemical profile and seasonal variation of phenolic acid content in bastard balm (Melittis melissophyllum L., Lamiaceae) . Journal of pharmaceutical and biomedical analysis, 2012, vol. 66, p. 154-161. DOI
- Maggi, F., Barboni, L., Caprioli, G., Papa, F., Ricciutelli, M., Sagratini, G., Vittori, S. HPLC quantification of coumarin in bastard balm (Melittis melissophyllum L., Lamiaceae) . Fitoterapia, 2011, vol. 82, no. 8, p. 1215-1221. DOI
- Maggi, Filippo., Conti, Fabio., Cristalli, Gloria., Giuliani, Claudia., Papa, Fabrizio., Sagratini, Gianni., Vittori, Sauro. Chemical Differences in Volatiles between Melittis melissophyllum L. subsp melissophyllum and subsp albida (Guss) P. W. Ball (Lamiaceae) Determined by Solid-Phase Microextraction (SPME) Coupled with GC/FID and GC/MS . Chemistry & biodiversity, 2011, vol. 8, no. 2, p. 325-343. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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