Botanical species · safety record

Melittis melissophyllum

The EFSA Compendium of Botanicals holds 15 constituent measurements for Melittis melissophyllum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Melittis melissophyllum L.

15Constituent measurements
0Safety records
4Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Coumarin6
  • 2-hydroxycinnamic acid2
  • 3,4-dihydroxybenzoic acid2
  • 4-hydroxybenzoic acid2
  • P-coumaric acid2
  • (-)-camphor1

Plant parts

  • Aerial part of plants11
  • Leaves4

Preparations

  • Solvent extraction12
  • Essential oil1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
(-)-camphorAerial part of plantsEssential oil3.61 PercentGC-MSResolve DOI
2-hydroxycinnamic acidAerial part of plantsSolvent extraction≤ 2.61 Milligram/100 gramHPLC-DADResolve DOI
2-hydroxycinnamic acidAerial part of plantsSolvent extraction≥ 0.63 Milligram/100 gramHPLC-DADResolve DOI
3,4-dihydroxybenzoic acidAerial part of plantsSolvent extraction≤ 8.22 Milligram/100 gramHPLC-DADResolve DOI
3,4-dihydroxybenzoic acidAerial part of plantsSolvent extraction≥ 2.1 Milligram/100 gramHPLC-DADResolve DOI
4-hydroxybenzoic acidAerial part of plantsSolvent extraction≤ 110.91 Milligram/100 gramHPLC-DADResolve DOI
4-hydroxybenzoic acidAerial part of plantsSolvent extraction≥ 30.21 Milligram/100 gramHPLC-DADResolve DOI
CoumarinLeavesSolvent extraction≤ 14392 Milligram/kilogramHPLC-DADResolve DOI
CoumarinLeavesSolvent extraction≤ 11125 Milligram/kilogramHPLC-DADResolve DOI
CoumarinLeavesSolvent extraction≥ 4588 Milligram/kilogramHPLC-DADResolve DOI
CoumarinLeavesSolvent extraction≥ 3091 Milligram/kilogramHPLC-DADResolve DOI
CoumarinAerial part of plants≤ 38.5 PercentGC-MSResolve DOI
CoumarinAerial part of plants≥ 0.2 PercentGC-MSResolve DOI
P-coumaric acidAerial part of plantsSolvent extraction≤ 121.4 Milligram/100 gramHPLC-DADResolve DOI
P-coumaric acidAerial part of plantsSolvent extraction≥ 40.48 Milligram/100 gramHPLC-DADResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Skaltsa-Diamantidis, H., Tsitsa-Tzardi, E., Tzakou, O., Argyriadou, N. Analysis of the essential oil of Melittis melissophyllum L. Subsp. albida Guss. Journal of essential oil research, 1991, vol. 3, no. 5, p. 367-368. DOI
  2. Skrzypczak-Pietraszek, Ewa., Pietraszek, Jacek. Chemical profile and seasonal variation of phenolic acid content in bastard balm (Melittis melissophyllum L., Lamiaceae) . Journal of pharmaceutical and biomedical analysis, 2012, vol. 66, p. 154-161. DOI
  3. Maggi, F., Barboni, L., Caprioli, G., Papa, F., Ricciutelli, M., Sagratini, G., Vittori, S. HPLC quantification of coumarin in bastard balm (Melittis melissophyllum L., Lamiaceae) . Fitoterapia, 2011, vol. 82, no. 8, p. 1215-1221. DOI
  4. Maggi, Filippo., Conti, Fabio., Cristalli, Gloria., Giuliani, Claudia., Papa, Fabrizio., Sagratini, Gianni., Vittori, Sauro. Chemical Differences in Volatiles between Melittis melissophyllum L. subsp melissophyllum and subsp albida (Guss) P. W. Ball (Lamiaceae) Determined by Solid-Phase Microextraction (SPME) Coupled with GC/FID and GC/MS . Chemistry & biodiversity, 2011, vol. 8, no. 2, p. 325-343. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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