Botanical species · safety record
Menispermum dauricum
The EFSA Compendium of Botanicals holds 43 constituent measurements for Menispermum dauricum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Menispermum dauricum DC.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 7 licensed products naming Menispermum dauricum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Isoquinoline alkaloids16
- Acutumine5
- Aporphine alkaloids4
- Dauricine4
- Magnoflorine3
- Norsinoacutine2
- Nuciferine2
- Sinomenine2
- Bisbenzylisoquinoline alkaloids1
- Moupinamide1
Plant parts
- Roots and other underground parts used as staple food35
- Roots and other underground parts7
- Unspecified1
Preparations
- Solvent extraction43
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Acutumine | Roots and other underground parts used as staple food | Solvent extraction | ≤ 1.61 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Acutumine | Roots and other underground parts used as staple food | Solvent extraction | ≥ 0.788 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Acutumine | Roots and other underground parts used as staple food | Solvent extraction | ≤ 0.804 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Acutumine | Roots and other underground parts used as staple food | Solvent extraction | ≥ 0.172 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Acutumine | Roots and other underground parts used as staple food | Solvent extraction | 1.65 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Aporphine alkaloids | Roots and other underground parts used as staple food | Solvent extraction | ≤ 11.03 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Aporphine alkaloids | Roots and other underground parts used as staple food | Solvent extraction | ≥ 7.74 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Aporphine alkaloids | Roots and other underground parts used as staple food | Solvent extraction | ≤ 0.083 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Aporphine alkaloids | Roots and other underground parts used as staple food | Solvent extraction | ≥ 0.008 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Bisbenzylisoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | 7.35 Milligram/gram | Chromatographic tests | Resolve DOI |
| Dauricine | Roots and other underground parts used as staple food | Solvent extraction | 21.38 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Dauricine | Roots and other underground parts used as staple food | Solvent extraction | ≤ 8.96 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Dauricine | Roots and other underground parts used as staple food | Solvent extraction | ≥ 4.39 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Dauricine | Roots and other underground parts used as staple food | Solvent extraction | 98.55 Milligram/gram | Chromatographic tests | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | ≤ 0.12 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | ≥ 0.013 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | 34.55 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | 2.9 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | 0.002 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | 2.55 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | 2.25 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts | Solvent extraction | — | Unspecified | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | 0.17 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | ≥ 0.011 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | ≤ 0.13 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Roots and other underground parts used as staple food | Solvent extraction | 2.65 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Magnoflorine | Roots and other underground parts used as staple food | Solvent extraction | ≥ 8.12 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Magnoflorine | Roots and other underground parts used as staple food | Solvent extraction | ≤ 17.42 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Moupinamide | Roots and other underground parts used as staple food | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Nuciferine | Roots and other underground parts used as staple food | Solvent extraction | ≤ 0.12 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Nuciferine | Roots and other underground parts used as staple food | Solvent extraction | ≥ 0.012 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Physcion | Roots and other underground parts used as staple food | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Sinomenine | Roots and other underground parts used as staple food | Solvent extraction | 9.3 Milligram/gram | Capillary (Zone) Electrophoresis (CE or CZE) | Resolve DOI |
| Stepholidine | Roots and other underground parts used as staple food | Solvent extraction | 0.036 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Tetrandrine | Roots and other underground parts used as staple food | Solvent extraction | 3.84 Milligram/gram | Capillary (Zone) Electrophoresis (CE or CZE) | Resolve DOI |
| Isoquinoline alkaloids | Unspecified | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| Isoquinoline alkaloids | Roots and other underground parts | Solvent extraction | — | LC-MS | No resolvable identifier |
| Isoquinoline alkaloids | Roots and other underground parts | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| Magnoflorine | Roots and other underground parts | Solvent extraction | — | LC-MS | No resolvable identifier |
40 of 43 records are shown, ordered so that records carrying a resolvable reference come first.
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Wei, Jinxia., Fang, Linlin., Liang, Xinlei., Su, Dan., Guo, Xingjie. A sensitive and selective UPLC-MS/MS method for simultaneous determination of 10 alkaloids from Rhizoma Menispermi in rat plasma and its application to a pharmacokinetic study . Talanta, 2015, vol. 144, p. 662-670. DOI
- Chen, Qinhua., Zhang, Juan., Zhang, Wenpeng., Chen, Zilin. Analysis of active alkaloids in the Menispermaceae family by nonaqueous capillary electrophoresis-ion trap mass spectrometry . Journal of separation science, 2013, vol. 36, no. 2, p. 341-349. DOI
- Sun, Dan., Zhou, Mengge., Ying, Xuhui., Cheng, Binfeng., Han, Yanqi., Nie, Yan., Hou, Yuanyuan., Bai, Gang. Identification of nuclear factor-kappaB inhibitors in the folk herb Rhizoma Menispermi via bioactivity-based ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry analysis. Bmc complementary and alternative medicine, 2014, vol. 14, p. 1-18.
- Chen Jian-Yong., Xie Yu-Feng., Zhou Tian-Xi., Qin Guo-Wei. Chemical constituents of Menispermum dauricum. Chinese journal of natural medicines, 2012, vol. 10, no. 4, p. 292-294. DOI
- Liu, Yanan., Song, Xiao., Yan, Ruiqing., Li, Tianxiang., Chai, Xin., Qi, Aidi., Wang, Yuefei., Jiang, Zhenzuo. Development and validation of a UPLC-DAD-MS method for characterization and quantification of alkaloids in Menispermi Rhizoma and its preparations . Journal of food and drug analysis, 2013, vol. 21, no. 2, p. 206-218. DOI
- Luo, Houding., Peng, Ming., Ye, Haoyu., Chen, Lijuan., Peng, Aihua., Tang, Minghai., Zhang, Fan., Shi, Jie. Predictable and linear scale-up of four phenolic alkaloids separation from the roots of Menispermum dauricum using high-performance counter-current chromatography . Journal of chromatography b-analytical technologies in the biomedical and life sciences, 2010, vol. 878, no. 22, p. 1929-1933. DOI
- Cong, Guo-yan., Yan, Yong-bo., Gao, Yu., Xu, Kai., Wang, Qi. Study on chemical constituents of Menispermum dauricum DC. Xiandai shengwuyixue jinzhan, 2013, vol. 13, no. 18, p. 3567-3569.
- Tang, Huang., Wang, Xiao-Dong., Wei, Yong-Biao., Huang, Shi-Liang., Huang, Zhi-Shu., Tan, Jia-Heng., An, Lin-Kun., Wu, Jian-Yong., Chan, Albert Sun-Chi., Gu, Lian-Quan. Oxoisoaporphine alkaloid derivatives: Synthesis, DNA binding affinity and cytotoxicity . European journal of medicinal chemistry, 2008, vol. 43, no. 5, p. 973-980. DOI
- Li, Shan-shan., Song, Xiao., Chai, Xin., Wang, Yue-fei. Chemical constituents in rhizome of menispermum dauricum DC.. Tianran chanwu yanjiu yu kaifa, 2013, vol. 25, no. 1, p. 60-63.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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