Botanical species · safety record

Menispermum dauricum

The EFSA Compendium of Botanicals holds 43 constituent measurements for Menispermum dauricum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Menispermum dauricum DC.

43Constituent measurements
0Safety records
9Cited sources
7Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 7 licensed products naming Menispermum dauricum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry

Source material stated

  • Dried rhizome
  • Rhizome

What the records describe

Constituents measured

  • Isoquinoline alkaloids16
  • Acutumine5
  • Aporphine alkaloids4
  • Dauricine4
  • Magnoflorine3
  • Norsinoacutine2
  • Nuciferine2
  • Sinomenine2
  • Bisbenzylisoquinoline alkaloids1
  • Moupinamide1

Plant parts

  • Roots and other underground parts used as staple food35
  • Roots and other underground parts7
  • Unspecified1

Preparations

  • Solvent extraction43

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AcutumineRoots and other underground parts used as staple foodSolvent extraction≤ 1.61 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
AcutumineRoots and other underground parts used as staple foodSolvent extraction≥ 0.788 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
AcutumineRoots and other underground parts used as staple foodSolvent extraction≤ 0.804 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
AcutumineRoots and other underground parts used as staple foodSolvent extraction≥ 0.172 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
AcutumineRoots and other underground parts used as staple foodSolvent extraction1.65 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Aporphine alkaloidsRoots and other underground parts used as staple foodSolvent extraction≤ 11.03 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Aporphine alkaloidsRoots and other underground parts used as staple foodSolvent extraction≥ 7.74 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Aporphine alkaloidsRoots and other underground parts used as staple foodSolvent extraction≤ 0.083 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Aporphine alkaloidsRoots and other underground parts used as staple foodSolvent extraction≥ 0.008 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Bisbenzylisoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction7.35 Milligram/gramChromatographic testsResolve DOI
DauricineRoots and other underground parts used as staple foodSolvent extraction21.38 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
DauricineRoots and other underground parts used as staple foodSolvent extraction≤ 8.96 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
DauricineRoots and other underground parts used as staple foodSolvent extraction≥ 4.39 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
DauricineRoots and other underground parts used as staple foodSolvent extraction98.55 Milligram/gramChromatographic testsResolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction≤ 0.12 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction≥ 0.013 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction34.55 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction2.9 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction0.002 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction2.55 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction2.25 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Isoquinoline alkaloidsRoots and other underground partsSolvent extractionUnspecifiedResolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction0.17 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction≥ 0.011 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction≤ 0.13 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Isoquinoline alkaloidsRoots and other underground parts used as staple foodSolvent extraction2.65 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
MagnoflorineRoots and other underground parts used as staple foodSolvent extraction≥ 8.12 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
MagnoflorineRoots and other underground parts used as staple foodSolvent extraction≤ 17.42 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
MoupinamideRoots and other underground parts used as staple foodSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
NuciferineRoots and other underground parts used as staple foodSolvent extraction≤ 0.12 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
NuciferineRoots and other underground parts used as staple foodSolvent extraction≥ 0.012 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
PhyscionRoots and other underground parts used as staple foodSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
SinomenineRoots and other underground parts used as staple foodSolvent extraction9.3 Milligram/gramCapillary (Zone) Electrophoresis (CE or CZE)Resolve DOI
StepholidineRoots and other underground parts used as staple foodSolvent extraction0.036 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
TetrandrineRoots and other underground parts used as staple foodSolvent extraction3.84 Milligram/gramCapillary (Zone) Electrophoresis (CE or CZE)Resolve DOI
Isoquinoline alkaloidsUnspecifiedSolvent extractionColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier
Isoquinoline alkaloidsRoots and other underground partsSolvent extractionLC-MSNo resolvable identifier
Isoquinoline alkaloidsRoots and other underground partsSolvent extractionColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier
MagnoflorineRoots and other underground partsSolvent extractionLC-MSNo resolvable identifier

40 of 43 records are shown, ordered so that records carrying a resolvable reference come first.

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Wei, Jinxia., Fang, Linlin., Liang, Xinlei., Su, Dan., Guo, Xingjie. A sensitive and selective UPLC-MS/MS method for simultaneous determination of 10 alkaloids from Rhizoma Menispermi in rat plasma and its application to a pharmacokinetic study . Talanta, 2015, vol. 144, p. 662-670. DOI
  2. Chen, Qinhua., Zhang, Juan., Zhang, Wenpeng., Chen, Zilin. Analysis of active alkaloids in the Menispermaceae family by nonaqueous capillary electrophoresis-ion trap mass spectrometry . Journal of separation science, 2013, vol. 36, no. 2, p. 341-349. DOI
  3. Sun, Dan., Zhou, Mengge., Ying, Xuhui., Cheng, Binfeng., Han, Yanqi., Nie, Yan., Hou, Yuanyuan., Bai, Gang. Identification of nuclear factor-kappaB inhibitors in the folk herb Rhizoma Menispermi via bioactivity-based ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry analysis. Bmc complementary and alternative medicine, 2014, vol. 14, p. 1-18.
  4. Chen Jian-Yong., Xie Yu-Feng., Zhou Tian-Xi., Qin Guo-Wei. Chemical constituents of Menispermum dauricum. Chinese journal of natural medicines, 2012, vol. 10, no. 4, p. 292-294. DOI
  5. Liu, Yanan., Song, Xiao., Yan, Ruiqing., Li, Tianxiang., Chai, Xin., Qi, Aidi., Wang, Yuefei., Jiang, Zhenzuo. Development and validation of a UPLC-DAD-MS method for characterization and quantification of alkaloids in Menispermi Rhizoma and its preparations . Journal of food and drug analysis, 2013, vol. 21, no. 2, p. 206-218. DOI
  6. Luo, Houding., Peng, Ming., Ye, Haoyu., Chen, Lijuan., Peng, Aihua., Tang, Minghai., Zhang, Fan., Shi, Jie. Predictable and linear scale-up of four phenolic alkaloids separation from the roots of Menispermum dauricum using high-performance counter-current chromatography . Journal of chromatography b-analytical technologies in the biomedical and life sciences, 2010, vol. 878, no. 22, p. 1929-1933. DOI
  7. Cong, Guo-yan., Yan, Yong-bo., Gao, Yu., Xu, Kai., Wang, Qi. Study on chemical constituents of Menispermum dauricum DC. Xiandai shengwuyixue jinzhan, 2013, vol. 13, no. 18, p. 3567-3569.
  8. Tang, Huang., Wang, Xiao-Dong., Wei, Yong-Biao., Huang, Shi-Liang., Huang, Zhi-Shu., Tan, Jia-Heng., An, Lin-Kun., Wu, Jian-Yong., Chan, Albert Sun-Chi., Gu, Lian-Quan. Oxoisoaporphine alkaloid derivatives: Synthesis, DNA binding affinity and cytotoxicity . European journal of medicinal chemistry, 2008, vol. 43, no. 5, p. 973-980. DOI
  9. Li, Shan-shan., Song, Xiao., Chai, Xin., Wang, Yue-fei. Chemical constituents in rhizome of menispermum dauricum DC.. Tianran chanwu yanjiu yu kaifa, 2013, vol. 25, no. 1, p. 60-63.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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