Botanical species · safety record

Mentha spicata

The EFSA Compendium of Botanicals holds 53 constituent measurements and 1 adverse-effect record for Mentha spicata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Mentha spicata L.

53Constituent measurements

1Safety records

7Cited sources

103Licensed products (Canada)

Also recorded as

Mentha crispa L.
Mentha viridis (L.) L.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 103 licensed products naming Mentha spicata as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Flower
Flowering twigs
Herb
Herb top
Herb top flowering
Leaf
Leaves
Mentha spicata - Twig flowering

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
(+)-pulegone	Aerial part of plants	Essential oil	72.1 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≤ 7 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≥ 1 Percent	GC-MS	Resolve DOI
Carvone	Aerial part of plants	Essential oil	≥ 59 Percent	GC-MS	Resolve DOI
Carvone	Aerial part of plants	Essential oil	67.1 Percent	GC-MS	Resolve DOI
Carvone	Aerial part of plants	Essential oil	≤ 77 Percent	GC-MS	Resolve DOI
Cis-piperitone epoxide	Aerial part of plants	Essential oil	23.8 Percent	GC-MS	Resolve DOI
D,l-isomenthone	Aerial part of plants	Essential oil	32 Percent	GC-MS	Resolve DOI
D,l-isomenthone	Aerial part of plants	Essential oil	2.6 Percent	GC-MS	Resolve DOI
Dihydrocarvone	Aerial part of plants	Essential oil	≤ 4 Percent	GC-MS	Resolve DOI
Dihydrocarvone	Aerial part of plants	Essential oil	≥ 1 Percent	GC-MS	Resolve DOI
Dihydrocarvone	Aerial part of plants	Essential oil	1 Percent	GC-MS	Resolve DOI
Menthone	Aerial part of plants	Essential oil	15.6 Percent	GC-MS	Resolve DOI
Menthone	Aerial part of plants	Essential oil	14 Percent	GC-MS	Resolve DOI
Myrcene	Aerial part of plants	Essential oil	2.1 Percent	GC-MS	Resolve DOI
Piperitenone oxide	Aerial part of plants	Essential oil	41 Percent	GC-MS	Resolve DOI
Piperitone oxide	Aerial part of plants	Essential oil	30 Percent	GC-MS	Resolve DOI
(+)-pulegone	Aerial part of plants	Essential oil	—	GC-MS	No resolvable identifier
1,8-cineole	Stem / stalk	Essential oil	≤ 25.4 Percent	GC-MS	No resolvable identifier
1,8-cineole	Stem / stalk	Essential oil	≥ 13.6 Percent	GC-MS	No resolvable identifier
1,8-cineole	Leaves	Essential oil	≤ 40.5 Percent	GC-MS	No resolvable identifier
1,8-cineole	Leaves	Essential oil	≥ 11.9 Percent	GC-MS	No resolvable identifier
1,8-cineole	Flowering top	Essential oil	≤ 13.5 Percent	GC-MS	No resolvable identifier
1,8-cineole	Flowering top	Essential oil	≥ 3.5 Percent	GC-MS	No resolvable identifier
Cis-piperitone epoxide	Leaves	Essential oil	≥ 1.5 Percent	GC-MS	No resolvable identifier
Cis-piperitone epoxide	Flowering top	Essential oil	≤ 5.9 Percent	GC-MS	No resolvable identifier
Cis-piperitone epoxide	Stem / stalk	Essential oil	≤ 7.8 Percent	GC-MS	No resolvable identifier
Cis-piperitone epoxide	Flowering top	Essential oil	≥ 3 Percent	GC-MS	No resolvable identifier
Cis-piperitone epoxide	Stem / stalk	Essential oil	≥ 3.3 Percent	GC-MS	No resolvable identifier
Cis-piperitone epoxide	Leaves	Essential oil	≤ 5.9 Percent	GC-MS	No resolvable identifier
Menthofuran	Aerial part of plants	Essential oil	—	GC-MS	No resolvable identifier
Menthone	Aerial part of plants	Essential oil	—	GC-MS	No resolvable identifier
Myrcene	Stem / stalk	Essential oil	≤ 13.5 Percent	GC-MS	No resolvable identifier
Myrcene	Stem / stalk	Essential oil	≥ 4.5 Percent	GC-MS	No resolvable identifier
Myrcene	Leaves	Essential oil	≤ 7.4 Percent	GC-MS	No resolvable identifier
Myrcene	Leaves	Essential oil	≥ 2.7 Percent	GC-MS	No resolvable identifier
Myrcene	Flowering top	Essential oil	≤ 6.7 Percent	GC-MS	No resolvable identifier
Myrcene	Flowering top	Essential oil	≥ 2.9 Percent	GC-MS	No resolvable identifier
Myrcene	Aerial part of plants	Essential oil	—	GC-MS	No resolvable identifier
Piperitenone oxide	Stem / stalk	Essential oil	≤ 24.8 Percent	GC-MS	No resolvable identifier

40 of 53 records are shown, ordered so that records carrying a resolvable reference come first.

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Endocrine	Testes	Leaves	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Sacco, Tommaso., Nano, Gian M. New plant for the essential oil literature. Botanical and chemical research. Rivista italiana essenze, profumi, piante officinali, aromi, saponi, cosmetici, aerosol, 1973, vol. 55, no. 4, p. 229-31.
Cook, Catherine M., Kokkini, Stella., Lanaras, Thomas. Mentha spicata essential oils rich in 1,8-cineole and 1,2-epoxy-P-menthane derivatives from Zakynthos (Ionian Island, W Greece) . Journal of essential oil research, 2007, vol. 19, no. 3, p. 225-230.
Koutroumanidou, Eleni., Kimbaris, Athanasios., Kortsaris, Alexandros., Bezirtzoglou, Eugenia., Polissiou, Moschos., Charalabopoulos, Konstantinos., Pagonopoulou, Olga. Increased seizure latency and decreased severity of pentylenetetrazol-induced seizures in mice after essential oil administration. . Epilepsy research and treatment, 2013, vol. 2013, p. 532657-532657. DOI
Baser, K. H. C., Kurkcuoglu, M., Demirci, B., Ozek, T., Tarimcilar, G. Essential oils of Mentha species from Marmara region of Turkey. JOURNAL OF ESSENTIAL OIL RESEARCH, 2012, vol. 24, no. 3, p. 265-272. DOI
Joshi, R. K. Pulegone and Menthone Chemotypes of Mentha spicata Linn. from Western Ghats Region of North West Karnataka, India . National academy science letters-india, 2013, vol. 36, no. 3, p. 349-352. DOI
Nozhat, Fatemeh., Alaee, Sanaz., Behzadi, Khodabakhsh., Azadi Chegini, Najmeh. Evaluation of possible toxic effects of spearmint (Mentha spicata) on the reproductive system, fertility and number of offspring in adult male rats. . Avicenna journal of phytomedicine, 2014, vol. 4, no. 6, p. 420-9.
Eliopoulos, P. A., Hassiotis, C. N., Andreadis, S. S., Porichi, A. -E. E. Fumigant Toxicity of Essential Oils from Basil and Spearmint Against Two Major Pyralid Pests of Stored Products. Journal of economic entomology, 2015, vol. 108, no. 2, p. 805-810. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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