Botanical species · safety record

Momordica charantia

The EFSA Compendium of Botanicals holds 2 constituent measurements and 2 genotoxicity assays for Momordica charantia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Momordica charantia L.

2Constituent measurements

2Safety records

3Cited sources

309Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 309 licensed products naming Momordica charantia as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh

Source material stated

Dried fruit powder
Flower
Fresh fruit
Fruit
Fruit (standardized extract)
Fruit extract
Fruit(s)
Leaf

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Fruit unspecified	Solvent extraction	—	Phytochemical screening	Resolve DOI
Coumarins	Fruit unspecified	Solvent extraction	—	Phytochemical screening	Resolve DOI

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Ambiguous	—	in vitro	Other	No data	Resolve DOI
Positive	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	Human (as organism)	No data	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Khatib, A., Perumal, V., Ahmed, Q. S., Uzir, B. F., Murugesu, S. Low inhibition of alpha-glucosidase and xanthine oxidase activities of ethanol extract of Momordica charantia fruit. Journal of pharmaceutical negative results, 2017, vol. 8, no. 1, p. 20-24. DOI
Basaran, AA., Yu, TW., Plewa, MJ., Anderson, D. An investigation of some turkish herbal medicines in Salmonella typhimurium and in the COMET assay in human lymphocytes. TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS, 1996, vol. 16, no. 2, p. 125-138. DOI
Ruiz, AR., delaTorre, RA., Alonso, N., Villaescusa, A., Betancourt, J., Vizoso, A. Screening of medicinal plants for induction of somatic segregation activity in Aspergillus nidulans. Journal of ethnopharmacology, 1996, vol. 52, no. 3, p. 123-127. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature