Botanical species · safety record

Momordica cochinchinensis

The EFSA Compendium of Botanicals holds 4 constituent measurements and 2 adverse-effect records for Momordica cochinchinensis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Momordica cochinchinensis (Lour.) Spreng.

4Constituent measurements

2Safety records

7Cited sources

19Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 19 licensed products naming Momordica cochinchinensis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Fruit
New material
Ripe seed(s)
Seed
Seed(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Saponins	Seed	Solvent extraction	—	Unspecified	Resolve DOI
Triterpene saponins	Unspecified	Solvent extraction	—	HPLC with standard detection methods	Resolve DOI
Momordin	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Momordin	Roots and other underground parts	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Reproductive	—	Seed	—	—	In vitro	Resolve DOI
Reproductive	Uterus	Roots and other underground parts	—	House mouse (as animal)	Reproduction toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

YEUNG, HW., NG, TB., WONG, NS., LI, WW. ISOLATION AND CHARACTERIZATION OF AN ABORTIFACIENT PROTEIN, MOMORCOCHIN, FROM ROOT TUBERS OF MOMORDICA-COCHINCHINENSIS (FAMILY CUCURBITACEAE) . International journal of peptide and protein research, 1987, vol. 30, no. 1, p. 135-140.
Arimatsu, Panida., Sawangsook, Orawan. Purification and Characterization of Trypsin Inhibitor from Momordica cochinchinensis Spreng. Seed and Its Effects to Spodoptera litura. Asian Journal of Plant Sciences, 2012, vol. 11, no. 4, p. 195-199. DOI
IWAMOTO, M., OKABE, H., YAMAUCHI, T. STUDIES ON THE CONSTITUENTS OF MOMORDICA-COCHINCHINENSIS SPRENG .2. ISOLATION AND CHARACTERIZATION OF THE ROOT SAPONINS, MOMORDIN-I, MOMORDIN-II AND MOMORDIN III . Chemical & pharmaceutical bulletin, 1985, vol. 33, no. 1, p. 1-7.
Jung, Kiwon., Chin, Young-Won., Chung, Yoon Hee., Park, Yang Hae., Yoo, Hunseung., Min, Dong Sun., Lee, Bongyong., Kim, Jinwoong. Anti-gastritis and wound healing effects of Momordicae Semen extract and its active component . Immunopharmacology and immunotoxicology, 2013, vol. 35, no. 1, p. 126-132. DOI
Lin, Zhi-Yan., Liu, Xiaoyun., Yang, Fan., Yu, Yun-Qiu. Structural characterization and identification of five triterpenoid saponins isolated from Momordica cochinchinensis extracts by liquid chromatography/tandem mass spectrometry. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2012, vol. 328, p. 43-66. DOI
Lin, Yau-Tang., Lo, Tung-Bin., Tai, Wun-Ten. Triterpenoids. I. The sugar constituents of some triterpenoid saponins from Formosan plants. Journal of the Chinese Chemical Society (Taipei, Taiwan), 1954, p. 57-63.
Wong, RCH., Fong, WP., Ng, TB. Multiple trypsin inhibitors from Momordica cochinchinensis seeds, the Chinese drug mubiezhi. PEPTIDES, 2004, vol. 25, no. 2, p. 163-169. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue

Independent literature