Botanical species · safety record

Montanoa tomentosa

The EFSA Compendium of Botanicals holds 14 constituent measurements and 5 adverse-effect records for Montanoa tomentosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Montanoa tomentosa Cerv.

14Constituent measurements

5Safety records

11Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Diterpenes	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Diterpenes	Leaves	Solvent extraction	—	—	Resolve DOI
Guaianolides	Leaves	Solvent extraction	0.009 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Guaianolides	Leaves	Solvent extraction	0.0022 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Guaianolides	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Guaianolides	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Guaianolides	Leaves	Solvent extraction	0.0027 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Kaurenoic acids	Leaves	Solvent extraction	—	—	Resolve DOI
Montanol	Leaves	Solvent extraction	—	Gaschromatography (GC)	Resolve DOI
Sesquiterpene lactones	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Zoapatanol	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Germacranolide	Aerial part of plants	Solvent extraction	—	—	No resolvable identifier
Isoquercitrin	Leaves	Solvent extraction	0.0018 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Sesquiterpene lactones	Aerial part of plants	Solvent extraction	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Developmental	Uterus	Leaves	Solvent extraction	Guinea pig (as animal)	Reproduction toxicity	Resolve DOI
Developmental	Uterus	Leaves	Solvent extraction	Rat (as animal)	Reproduction toxicity	Resolve DOI
Developmental	Uterus	Leaves	Solvent extraction	Guinea pig (as animal)	Reproduction toxicity	Resolve DOI
Developmental	Uterus	Leaves	Solvent extraction	House mouse (as animal)	Reproduction toxicity	Resolve DOI
Reproductive	Urogenital	Aerial part of plants	Solvent extraction	Rat (as animal)	Reproduction toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

HAHN, DW., ERICSON, EW., LAI, MT., PROBST, A. ANTI-FERTILITY ACTIVITY OF MONTANOA-TOMENTOSA (ZOAPATLE). Contraception, 1981, vol. 23, no. 2, p. 133-140. DOI
Carro-Juarez, M., Cervantes, E., Cervantes-Mendez, M., Rodriguez-Manzo, G. Aphrodisiac properties of Montanoa tomentosa aqueous crude extract in male rats . Pharmacology biochemistry and behavior, 2004, vol. 78, no. 1, p. 129-134. DOI
LIDIAPEREZ, A., CABALLERO, MBA., ORTEGA, A., GAVINO, R., DEVIVAR, AR. NEW SESQUITERPENE LACTONES FROM MONTANOA-TOMENTOSA SUBSP XANTHIIFOLIA. Planta medica, 1994, vol. 60, no. 3, p. 263-266. DOI
KANOJIA, RM., WACHTER, MP., LEVINE, SD., ADAMS, RE., CHEN, R., CHIN, E., COTTER, ML., HIRSCH, AF., HUETTEMANN, R., KANE, VV., OSTROWSKI, P., SHAW, CJ., MATEOS, JL., NORIEGA, L., GUZMAN, A., MIJAREZ, A., TOVAR, L., SHEFTER, E. ISOLATION AND STRUCTURAL ELUCIDATION OF ZOAPATANOL AND MONTANOL, NOVEL OXEPANE DITERPENOIDS FROM THE MEXICAN PLANT ZOAPATLE (MONTANOA-TOMENTOSA) . Journal of organic chemistry, 1982, vol. 47, no. 7, p. 1310-1319. DOI
Braca, A., Cioffi, G., Morelli, I., Venturella, F., Pizza, C., De Tommasi, N. Two new sesquiterpene lactones from Montanoa tomentosa ssp microcephala. Planta medica, 2001, vol. 67, no. 8, p. 774-776.
QUIJANO, L., GOMEZ, F., SIERRA, E., RIOS, T. ACYCLIC DITERPENES AND SESQUITERPENE LACTONES FROM MONTANOA-TOMENTOSA SUBSP TOMENTOSA . Phytochemistry, 1991, vol. 30, no. 6, p. 1947-1950. DOI
Enriquez, RG., Miranda, E., Ortiz, B., Leon, I., Magos, G., Pena, A., Reynolds, WF., Gnecco, D. The unambiguous detection of kaurenic derivatives in aqueous infusions of Montanoa tomentosa by GC-MS and 2D-NMR spectroscopy: An answer to contradictory reports . Planta medica, 1996, vol. 62, no. 6, p. 569-571. DOI
TOPCU, G., CORDELL, GA., FARNSWORTH, NR., FONG, HHS. STUDIES ON ZOAPATLE .8. NOVEL CYTO-TOXIC SESQUITERPENE LACTONES FROM MONTANOA-TOMENTOSA SSP MICROCEPHALA . Journal of pharmaceutical sciences, 1988, vol. 77, no. 6, p. 553-556. DOI
QUIJANO, L., CALDERON, JS., GOMEZ, F., RIOS, T. ZOAPATANOLIDE-A AND ZOAPATANOLIDE-B, 2 NEW HELIANGOLIDES FROM MONTANOA-TOMENTOSA . Phytochemistry, 1982, vol. 21, no. 8, p. 2041-2044. DOI
Oshima, Yoshiteru., Gordell, Geoffrey A., Fong, Harry H. S. Studies on zoapatle. III. Flavonoid glycosides from Montanoa tomentosa ssp. tomentosa. Journal of natural products, 1986, vol. 49, no. 3, p. 551-2.
MARCELLE, GB., BUNYAPRAPHATSARA, N., CORDELL, GA., FONG, HHS., NICOLAOU, KC., ZIPKIN, RE. STUDIES OF ZOAPATLE .1. THE EXTRACTION OF ZOAPATLE (MONTANOA-TOMENTOSA) AND THE IDENTIFICATION OF 21-NORMONTANOL AS THE INITIAL DECOMPOSITION PRODUCT OF ZOAPATANOL . Journal of natural products, 1985, vol. 48, no. 5, p. 739-745. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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