Botanical species · safety record

Morinda citrifolia

The EFSA Compendium of Botanicals holds 3 constituent measurements and 3 adverse-effect records for Morinda citrifolia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Morinda citrifolia L.

3Constituent measurements
3Safety records
5Cited sources
141Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 141 licensed products naming Morinda citrifolia as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Fresh

Source material stated

  • Fruit
  • Fruit Juice
  • Fruit extract
  • Fruit fibre
  • Fruit(s)
  • Juice
  • Leaf
  • Morinda citrifolia, freeze-dried juice powder

What the records describe

Constituents measured

  • Anthraquinones1
  • Lignans1
  • Scopoletin1

Plant parts

  • Fruit unspecified5
  • Roots and other underground parts1

Preparations

  • Solvent extraction5

Effect types

  • Developmental1
  • Endocrine1
  • Hepatotoxicity1

Target tissues

  • Bone (deprecated)1
  • Liver1
  • Uterus1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AnthraquinonesRoots and other underground partsSolvent extractionHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
LignansFruit unspecifiedSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
ScopoletinFruit unspecifiedSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DevelopmentalBone (deprecated)Fruit unspecifiedSolvent extractionRat (as animal)Reproduction toxicityResolve DOI
EndocrineUterusFruit unspecifiedSolvent extractionHouse mouse (as animal)Reproduction toxicityResolve DOI
HepatotoxicityLiverFruit unspecifiedHuman (as organism)Case reportNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Quallio Marques, Nelson Fernando., Bombonatto Mariano Marques, Ana Paula., Iwano, Ana Livia., Golina, Munisa., De-Carvalho, Rosangela Ribeiro., Roma Paumgartten, Francisco Jose., Dalsenter, Paulo Roberto. Delayed ossification in Wistar rats induced by Morinda citrifolia L. exposure during pregnancy . Journal of ethnopharmacology, 2010, vol. 128, no. 1, p. 85-91. DOI
  2. Mueller, Juliane C., Botelho, Giuliana G. K., Bufalo, Aedra C., Boareto, Ana C., Rattmann, Yanna D., Martins, Elisangela S., Cabrini, Daniela A., Otuki, Michel F., Dalsenter, Paulo R. Morinda citrifolia Linn (Noni): In vivo and in vitro reproductive toxicology . Journal of ethnopharmacology, 2009, vol. 121, no. 2, p. 29-33. DOI
  3. Abdualmjid, R.J., Sergi, C. Hepatotoxic botanicals - An evidence-based systematic review. Journal of pharmacy and pharmaceutical sciences, 2013, vol. 16, no. 3, p. 376-404.
  4. Westendorf, Johannes., Effenberger, Katharina., Iznaguen, Hassan., Basar, Simla. Toxicological and analytical investigations of noni (Morinda citrifolia) fruit juice . Journal of agricultural and food chemistry, 2007, vol. 55, no. 2, p. 529-537. DOI
  5. Lin, Chwan Fwu., Ni, Ching Li., Huang, Yu Ling., Sheu, Shuenn Jyi., Chen, Chien Chih. Lignans and anthraquinones from the fruits of Morinda citrifolia. Natural product research, 2007, vol. 21, no. 13, p. 1199-1204. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue