Botanical species · safety record

Morus alba

The EFSA Compendium of Botanicals holds 5 constituent measurements and 7 adverse-effect records for Morus alba. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Morus alba L.

5Constituent measurements

7Safety records

5Cited sources

661Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 661 licensed products naming Morus alba as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
decoction
fluid

Source material stated

Bark
Bark (dry-fried)
Branch(es)
Cortex
Dried leaf
Dried root-bark
Fruit
Fruit extract

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Coumarins	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Piperidine alkaloids	Leaves	Solvent extraction	0.11 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Proanthocyanidins (condensed tannins)	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Coumarins	Leaves	Solvent extraction	—	—	No resolvable identifier
Melatonin	Leaves	Solvent extraction	—	Unspecified	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	—	—	—	In vitro	Resolve DOI
Digestive	Digestive	Leaves	Solvent extraction	—	In vitro	Resolve DOI
Digestive	Digestive	Leaves	Solvent extraction	—	In vitro	Resolve DOI
Hemopoietic	Cardiovascular / haematological	Leaves	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Hepatotoxicity	Liver	Leaves	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	Leaves	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Digestive	Digestive: pancreas	Leaves	Solvent extraction	—	In vitro	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Nickavar, Bahman., Mosazadeh, Golboo. Influence of Three Morus Species Extracts on alpha-Amylase Activity. Iranian journal of pharmaceutical research, 2009, vol. 8, no. 2, p. 115-119.
de Oliveira, Alisson Macario., Mesquita, Matheus da Silva., da Silva, Gabriela Cavalcante., de Oliveira Lima, Edeltrudes., de Medeiros, Paloma Lys., Paiva, Patricia Maria Guedes., de Souza, Ivone Antonia., Napoleao, Thiago Henrique. Evaluation of Toxicity and Antimicrobial Activity of an Ethanolic Extract from Leaves of Morus alba L. (Moraceae). . Evidence-based complementary and alternative medicine : ecam, 2015, vol. 2015, p. 513978-513978. DOI
Kim, Gyo-Nam., Kwon, Young-In., Jang, Hae-Dong. Mulberry Leaf Extract Reduces Postprandial Hyperglycemia with Few Side Effects by Inhibiting alpha-Glucosidase in Normal Rats . Journal of medicinal food, 2011, vol. 14, no. 7-8, p. 712-717. DOI
Gummadi, H., Vinay Kumar, K., Manohar Reddy, E., Rajesh Kumar, J., Ganesan, A.S.K., Veera Reddy, Y., Akbar, M.D. Chemomodulatory influence of melatonin rich Morus alba L. on n-methyl-n-nitrosourea (NMU) induced mammary carcinoma in Sprague-Dawley rats. Research journal of pharmaceutical, biological and chemical sciences, 2012, vol. 3, no. 4, p. 994-1000.
de Oliveira Alisson Macario., Mesquita Matheus da Silva., da Silva Gabriela Cavalcante., de Souza Ivone Antonia., de Oliveira Lima Edeltrudes., de Medeiros Paloma Lys., Paiva Patricia Maria Guedes., Napoleao Thiago Henrique. Evaluation of Toxicity and Antimicrobial Activity of an Ethanolic Extract from Leaves of Morus alba L. (Moraceae). Evidence-based complementary and alternative medicine : ecam, 2015.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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