Botanical species · safety record

Narcissus pseudonarcissus

The EFSA Compendium of Botanicals holds 49 constituent measurements and 2 adverse-effect records for Narcissus pseudonarcissus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Narcissus pseudonarcissus L.

49Constituent measurements
2Safety records
12Cited sources
1Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Narcissus pseudonarcissus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Whole plant

What the records describe

Constituents measured

  • Galanthamine10
  • Alkaloids9
  • Haemanthamine9
  • Daidzein2
  • Daidzin2
  • Narwedine2
  • Oduline2
  • Pseudolycorine2
  • Caranine1
  • Formononetin1

Plant parts

  • Bulb38
  • clove38
  • Leaves9
  • Roots and other underground parts3
  • Stem1
  • stalk1

Preparations

  • Solvent extraction48

Effect types

  • Digestive1
  • Hepatotoxicity1

Target tissues

  • Digestive1
  • Lung1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsBulb / cloveSolvent extraction≥ 0.5 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
AlkaloidsBulb / cloveSolvent extraction≤ 0.6 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
AlkaloidsLeavesSolvent extraction≥ 0.8 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
AlkaloidsBulb / cloveSolvent extraction2 Microgram/gramGaschromatography (GC)Resolve DOI
AlkaloidsLeavesSolvent extraction≤ 2.2 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
AlkaloidsBulb / cloveSolvent extractionChromatographic testsResolve DOI
AlkaloidsBulb / cloveSolvent extractionGaschromatography (GC)Resolve DOI
GalanthamineBulb / cloveSolvent extraction4 Microgram/gramGaschromatography (GC)Resolve DOI
GalanthamineBulb / cloveSolvent extractionGaschromatography (GC)Resolve DOI
GalanthamineBulb / cloveSolvent extractionGaschromatography (GC)Resolve DOI
GalanthamineBulb / cloveSolvent extraction≥ 2 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
GalanthamineBulb / cloveSolvent extractionGaschromatography (GC)Resolve DOI
GalanthamineRoots and other underground partsSolvent extraction3 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
GalanthamineLeavesSolvent extraction≤ 2 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
GalanthamineLeavesSolvent extraction≥ 1 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
GalanthamineBulb / cloveSolvent extraction≤ 2.8 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
GalanthineBulb / cloveSolvent extractionGaschromatography (GC)Resolve DOI
HaemanthamineRoots and other underground partsSolvent extraction≤ 4 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
HaemanthamineBulb / cloveSolvent extraction3 Microgram/gramGaschromatography (GC)Resolve DOI
HaemanthamineBulb / cloveSolvent extraction≥ 0.7 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
HaemanthamineBulb / cloveSolvent extraction≤ 0.9 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
HaemanthamineLeavesSolvent extraction≥ 1 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
HaemanthamineBulb / cloveSolvent extractionGaschromatography (GC)Resolve DOI
HaemanthamineRoots and other underground partsSolvent extraction≥ 2 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
HaemanthamineLeavesSolvent extraction≤ 5.5 Milligram/gramNuclear Magnetic Resonance (NMR)Resolve DOI
HomolycorineBulb / cloveSolvent extractionGaschromatography (GC)Resolve DOI
LectinsBulb / cloveStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
LycorenineBulb / cloveSolvent extractionGaschromatography (GC)Resolve DOI
MasonineBulb / cloveSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
NarwedineBulb / cloveSolvent extraction15 Microgram/gramGaschromatography (GC)Resolve DOI
OdulineBulb / cloveSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
OdulineBulb / cloveSolvent extraction4 Microgram/gramGaschromatography (GC)Resolve DOI
PseudolycorineBulb / cloveSolvent extractionGaschromatography (GC)Resolve DOI
PseudolycorineBulb / cloveSolvent extractionGaschromatography (GC)Resolve DOI
AlkaloidsBulb / cloveSolvent extraction7 PercentGC-MSNo resolvable identifier
AlkaloidsBulb / cloveSolvent extractionGelpermeation, High Performance Thin Layer Chromatography (HPTLC)No resolvable identifier
CaranineBulb / cloveSolvent extraction6 PercentGC-MSNo resolvable identifier
DaidzeinBulb / cloveSolvent extraction≤ 35.2 Nanogram/gramHPLC with standard detection methodsNo resolvable identifier
DaidzeinBulb / cloveSolvent extraction≥ 25.7 Nanogram/gramHPLC with standard detection methodsNo resolvable identifier
DaidzinBulb / cloveSolvent extraction≤ 66.5 Nanogram/gramHPLC with standard detection methodsNo resolvable identifier

40 of 49 records are shown, ordered so that records carrying a resolvable reference come first.

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DigestiveDigestiveStem / stalkCat (as animal)Case reportNo resolvable identifier
HepatotoxicityLungBulb / cloveHuman (as organism)Case reportNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Lubbe, Andrea., Gude, Henk., Verpoorte, Robert., Choi, Young Hae. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton . Phytochemistry, 2013, vol. 88, p. 43-53. DOI
  2. Rachmaniah, Orchidea., Choi, Young Hae., Arruabarrena, Inaki., Vermeulen, Bas., van Spronsen, Jaap., Verpoorte, Robert., Witkarnp, Geert-Jan. Environmentally benign supercritical CO2 extraction of galanthamine from floricultural crop waste of Narcissus pseudo narcissus . Journal of supercritical fluids, 2014, vol. 93, p. 7-19. DOI
  3. Fales, H.M., Giuffrida, L.D., Wildman, W.C. Alkaloids of the amaryllidaceae. VIII. The structures of narcissamine, pseudolycorine and methylpseudolycorine. Journal of the american chemical society, 1956, vol. 78, no. 16, p. 4145-4150. DOI
  4. KAKU, H., GOLDSTEIN, IJ. INTERACTION OF LINEAR MANNO-OLIGOSACCHARIDES WITH 3 MANNOSE-SPECIFIC BULB LECTINS - COMPARISON WITH MANNOSE GLUCOSE-BINDING LECTINS . Carbohydrate research, 1992, vol. 229, no. 2, p. 337-346. DOI
  5. Miksatkova, Petra., Lankova, Petra., Huml, Lukas., Lapcik, Oldrich. Isoflavonoids in the Amaryllidaceae family. Natural product research, 2014, vol. 28, no. 10, p. 690-697.
  6. Cahl�kov�, L., Loc�rek, M., Benesov�, N., Kucera, R., Chlebek, J., Nov�k, Z., Opletal, L. Isolation and cholinesterase inhibitory activity of Narcissus extracts and amaryllidaceae alkaloid. Natural product communications, 2013, vol. 8, no. 6, p. 781-785.
  7. KREH, M., MATUSCH, R. O-METHYLODULINE AND N-DEMETHYLMASONINE, ALKALOIDS FROM NARCISSUS-PSEUDONARCISSUS . Phytochemistry, 1995, vol. 38, no. 6, p. 1533-1535. DOI
  8. KREH, M., MATUSCH, R., WITTE, L. CAPILLARY GAS-CHROMATOGRAPHY MASS-SPECTROMETRY OF AMARYLLIDACEAE ALKALOIDS . Phytochemistry, 1995, vol. 38, no. 3, p. 773-776. DOI
  9. Hammoda, Hala M., Abou-Donia, Amina H., Toaima, Soaad M., Shawky, Eman A. Acetylcholinesterase inhibitory activity of some amaryllidaceae plant extracts and alkaloidal isolates. Alexandria journal of pharmaceutical sciences, 2011, vol. 25, no. 1, p. 26-28.
  10. Saxon-Buri, S. Daffodil toxicosis in an adult cat. Canadian veterinary journal, 2004, vol. 45, no. 3, p. 248-250.
  11. JaspersenSchib, R., Theus, L., GuirguisOeschger, M., Gossweiler, B., MeierAbt, PJ. Acute poisonings with toxic giants in Switzerland between 1966 and 1994. Schweizerische medizinische wochenschrift, 1996, vol. 126, no. 25, p. 1085-1098.
  12. KREH, M., MATUSCH, R., WITTE, L. ACETYLATED ALKALOIDS FROM NARCISSUS-PSEUDONARCISSUS. Phytochemistry, 1995, vol. 40, no. 4, p. 1303-1306. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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