Botanical species · safety record
Narcissus pseudonarcissus
The EFSA Compendium of Botanicals holds 49 constituent measurements and 2 adverse-effect records for Narcissus pseudonarcissus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Narcissus pseudonarcissus L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Narcissus pseudonarcissus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- Galanthamine10
- Alkaloids9
- Haemanthamine9
- Daidzein2
- Daidzin2
- Narwedine2
- Oduline2
- Pseudolycorine2
- Caranine1
- Formononetin1
Plant parts
- Bulb38
- clove38
- Leaves9
- Roots and other underground parts3
- Stem1
- stalk1
Preparations
- Solvent extraction48
Effect types
- Digestive1
- Hepatotoxicity1
Target tissues
- Digestive1
- Lung1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Bulb / clove | Solvent extraction | ≥ 0.5 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Alkaloids | Bulb / clove | Solvent extraction | ≤ 0.6 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Alkaloids | Leaves | Solvent extraction | ≥ 0.8 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Alkaloids | Bulb / clove | Solvent extraction | 2 Microgram/gram | Gaschromatography (GC) | Resolve DOI |
| Alkaloids | Leaves | Solvent extraction | ≤ 2.2 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Alkaloids | Bulb / clove | Solvent extraction | — | Chromatographic tests | Resolve DOI |
| Alkaloids | Bulb / clove | Solvent extraction | — | Gaschromatography (GC) | Resolve DOI |
| Galanthamine | Bulb / clove | Solvent extraction | 4 Microgram/gram | Gaschromatography (GC) | Resolve DOI |
| Galanthamine | Bulb / clove | Solvent extraction | — | Gaschromatography (GC) | Resolve DOI |
| Galanthamine | Bulb / clove | Solvent extraction | — | Gaschromatography (GC) | Resolve DOI |
| Galanthamine | Bulb / clove | Solvent extraction | ≥ 2 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Galanthamine | Bulb / clove | Solvent extraction | — | Gaschromatography (GC) | Resolve DOI |
| Galanthamine | Roots and other underground parts | Solvent extraction | 3 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Galanthamine | Leaves | Solvent extraction | ≤ 2 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Galanthamine | Leaves | Solvent extraction | ≥ 1 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Galanthamine | Bulb / clove | Solvent extraction | ≤ 2.8 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Galanthine | Bulb / clove | Solvent extraction | — | Gaschromatography (GC) | Resolve DOI |
| Haemanthamine | Roots and other underground parts | Solvent extraction | ≤ 4 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Haemanthamine | Bulb / clove | Solvent extraction | 3 Microgram/gram | Gaschromatography (GC) | Resolve DOI |
| Haemanthamine | Bulb / clove | Solvent extraction | ≥ 0.7 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Haemanthamine | Bulb / clove | Solvent extraction | ≤ 0.9 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Haemanthamine | Leaves | Solvent extraction | ≥ 1 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Haemanthamine | Bulb / clove | Solvent extraction | — | Gaschromatography (GC) | Resolve DOI |
| Haemanthamine | Roots and other underground parts | Solvent extraction | ≥ 2 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Haemanthamine | Leaves | Solvent extraction | ≤ 5.5 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Homolycorine | Bulb / clove | Solvent extraction | — | Gaschromatography (GC) | Resolve DOI |
| Lectins | Bulb / clove | — | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Lycorenine | Bulb / clove | Solvent extraction | — | Gaschromatography (GC) | Resolve DOI |
| Masonine | Bulb / clove | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Narwedine | Bulb / clove | Solvent extraction | 15 Microgram/gram | Gaschromatography (GC) | Resolve DOI |
| Oduline | Bulb / clove | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Oduline | Bulb / clove | Solvent extraction | 4 Microgram/gram | Gaschromatography (GC) | Resolve DOI |
| Pseudolycorine | Bulb / clove | Solvent extraction | — | Gaschromatography (GC) | Resolve DOI |
| Pseudolycorine | Bulb / clove | Solvent extraction | — | Gaschromatography (GC) | Resolve DOI |
| Alkaloids | Bulb / clove | Solvent extraction | 7 Percent | GC-MS | No resolvable identifier |
| Alkaloids | Bulb / clove | Solvent extraction | — | Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) | No resolvable identifier |
| Caranine | Bulb / clove | Solvent extraction | 6 Percent | GC-MS | No resolvable identifier |
| Daidzein | Bulb / clove | Solvent extraction | ≤ 35.2 Nanogram/gram | HPLC with standard detection methods | No resolvable identifier |
| Daidzein | Bulb / clove | Solvent extraction | ≥ 25.7 Nanogram/gram | HPLC with standard detection methods | No resolvable identifier |
| Daidzin | Bulb / clove | Solvent extraction | ≤ 66.5 Nanogram/gram | HPLC with standard detection methods | No resolvable identifier |
40 of 49 records are shown, ordered so that records carrying a resolvable reference come first.
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Digestive | Digestive | Stem / stalk | — | Cat (as animal) | Case report | No resolvable identifier |
| Hepatotoxicity | Lung | Bulb / clove | — | Human (as organism) | Case report | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Lubbe, Andrea., Gude, Henk., Verpoorte, Robert., Choi, Young Hae. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton . Phytochemistry, 2013, vol. 88, p. 43-53. DOI
- Rachmaniah, Orchidea., Choi, Young Hae., Arruabarrena, Inaki., Vermeulen, Bas., van Spronsen, Jaap., Verpoorte, Robert., Witkarnp, Geert-Jan. Environmentally benign supercritical CO2 extraction of galanthamine from floricultural crop waste of Narcissus pseudo narcissus . Journal of supercritical fluids, 2014, vol. 93, p. 7-19. DOI
- Fales, H.M., Giuffrida, L.D., Wildman, W.C. Alkaloids of the amaryllidaceae. VIII. The structures of narcissamine, pseudolycorine and methylpseudolycorine. Journal of the american chemical society, 1956, vol. 78, no. 16, p. 4145-4150. DOI
- KAKU, H., GOLDSTEIN, IJ. INTERACTION OF LINEAR MANNO-OLIGOSACCHARIDES WITH 3 MANNOSE-SPECIFIC BULB LECTINS - COMPARISON WITH MANNOSE GLUCOSE-BINDING LECTINS . Carbohydrate research, 1992, vol. 229, no. 2, p. 337-346. DOI
- Miksatkova, Petra., Lankova, Petra., Huml, Lukas., Lapcik, Oldrich. Isoflavonoids in the Amaryllidaceae family. Natural product research, 2014, vol. 28, no. 10, p. 690-697.
- Cahl�kov�, L., Loc�rek, M., Benesov�, N., Kucera, R., Chlebek, J., Nov�k, Z., Opletal, L. Isolation and cholinesterase inhibitory activity of Narcissus extracts and amaryllidaceae alkaloid. Natural product communications, 2013, vol. 8, no. 6, p. 781-785.
- KREH, M., MATUSCH, R. O-METHYLODULINE AND N-DEMETHYLMASONINE, ALKALOIDS FROM NARCISSUS-PSEUDONARCISSUS . Phytochemistry, 1995, vol. 38, no. 6, p. 1533-1535. DOI
- KREH, M., MATUSCH, R., WITTE, L. CAPILLARY GAS-CHROMATOGRAPHY MASS-SPECTROMETRY OF AMARYLLIDACEAE ALKALOIDS . Phytochemistry, 1995, vol. 38, no. 3, p. 773-776. DOI
- Hammoda, Hala M., Abou-Donia, Amina H., Toaima, Soaad M., Shawky, Eman A. Acetylcholinesterase inhibitory activity of some amaryllidaceae plant extracts and alkaloidal isolates. Alexandria journal of pharmaceutical sciences, 2011, vol. 25, no. 1, p. 26-28.
- Saxon-Buri, S. Daffodil toxicosis in an adult cat. Canadian veterinary journal, 2004, vol. 45, no. 3, p. 248-250.
- JaspersenSchib, R., Theus, L., GuirguisOeschger, M., Gossweiler, B., MeierAbt, PJ. Acute poisonings with toxic giants in Switzerland between 1966 and 1994. Schweizerische medizinische wochenschrift, 1996, vol. 126, no. 25, p. 1085-1098.
- KREH, M., MATUSCH, R., WITTE, L. ACETYLATED ALKALOIDS FROM NARCISSUS-PSEUDONARCISSUS. Phytochemistry, 1995, vol. 40, no. 4, p. 1303-1306. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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