Botanical species · safety record

Nardostachys jatamansi

The EFSA Compendium of Botanicals holds 13 constituent measurements, 1 adverse-effect record and 1 genotoxicity assay for Nardostachys jatamansi. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Nardostachys jatamansi (D.Don) DC.

13Constituent measurements

2Safety records

7Cited sources

0Licensed products (Canada)

Also recorded as

Nardostachys grandiflora DC.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Coumarins	Roots and other underground parts	Essential oil	—	Unspecified	Resolve DOI
Neolignans	Roots and other underground parts	—	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
1,8-cineole	Roots and other underground parts	Solvent extraction	0.02 Percent	GC-MS	No resolvable identifier
1,8-cineole	Roots and other underground parts	Essential oil	≤ 2.3 Percent	GC-MS	No resolvable identifier
1,8-cineole	Roots and other underground parts	Essential oil	≥ 0.2 Percent	GC-MS	No resolvable identifier
Actinidine	Roots and other underground parts	Solvent extraction	2.22 Percent	GC-MS	No resolvable identifier
Alkaloids	Roots and other underground parts	Solvent extraction	—	—	No resolvable identifier
Coumarins	Roots and other underground parts	Solvent extraction	—	—	No resolvable identifier
Epoxides	Roots and other underground parts	Solvent extraction	0.59 Percent	GC-MS	No resolvable identifier
Lignans	Roots and other underground parts	Solvent extraction	—	—	No resolvable identifier
Myrcene	Roots and other underground parts	Essential oil	≥ 0.2 Percent	GC-MS	No resolvable identifier
Myrcene	Roots and other underground parts	Essential oil	≤ 2.3 Percent	GC-MS	No resolvable identifier
Neolignans	Roots and other underground parts	Solvent extraction	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic: central nervous system	Roots and other underground parts	Solvent extraction	Rat (as animal)	Not reported	Resolve DOI

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	Human (as organism)	—	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Rao, VS., Rao, A., Karanth, KS. Anticonvulsant and neurotoxicity profile of Nardostachys jatamansi in rats . Journal of ethnopharmacology, 2005, vol. 102, no. 3, p. 351-356. DOI
Etebari, Mahmoud., Zolfaghari, Behzad., Jafarian-Dehkordi, Abbas., Rakian, Roya. Evaluation of DNA damage of hydro-alcoholic and aqueous extract of Echium amoenum and Nardostachys jatamansi . Journal of research in medical sciences, 2012, vol. 17, no. 8, p. 782-786.
Veena, M.E., Niranjana, P., Achur, R.N. Gas chromatography-mass spectrometry analysis of bioactive components from the rhizome extract of Nardostachys jatamansi DC. Asian journal of pharmaceutical and clinical research, 2016, vol. 9, no. 3.
Purnima., Bhatt, Meenakshi., Kothiyal, Preeti. A review article on phytochemistry and pharmacological profiles of Nardostachys jatamansi DC-medicinal herb. Journal of pharmacognosy and phytochemistry, 2015, vol. 3, no. 5, p. 102-106.
Purohit, V.K., Andola, H.C., Bahuguna, Y.M., Gairola, K.C., Haider, S.Z., Arunachalam, K. Volatile constituents of endangered species Nardostachys grandiflora DC. Rhizomes from Uttarakhand Himalaya (India). Indian journal of natural products and resources, 2015, vol. 6, no. 2, p. 134-137.
REILLY, MJ., WALLIS, AFA., LUNDQUIST, K., STOMBERG, R. STEREOCHEMISTRY OF NEOLIGNANS - A REVISED STRUCTURE FOR A NEOLIGNAN ISOLATED FROM THE ROOTS OF PIPER-CAPENSE . Journal of wood chemistry and technology, 1992, vol. 12, no. 4, p. 471-483. DOI
SHANBHAG, SN., MESTA, CK., MAHESHWA.ML., BHATTACH.SC. TERPENOIDS .75. CONSTITUENTS OF NARDOSTACHYS JATAMANSI AND SYNTHESIS OF (+-) DIHYDROSAMIDIN FROM JATAMANSIN . Tetrahedron, 1965, vol. 21, no. 12, p. 3591-&. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature