Botanical species · safety record

Nigella damascena

The EFSA Compendium of Botanicals holds 19 constituent measurements for Nigella damascena. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Nigella damascena L.

19Constituent measurements
0Safety records
5Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Alpha-selinene6
  • Damascenine5
  • Naphthalene derivatives4
  • Beta-​selinene2
  • Alkaloids1
  • Diterpene esters1

Plant parts

  • Seed19

Preparations

  • Solvent extraction13
  • Essential oil6

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Alpha-selineneSeedSolvent extraction≤ 0.55 PercentGC-FID-MSResolve DOI
Alpha-selineneSeedSolvent extraction≥ 0.05 PercentGC-FID-MSResolve DOI
Alpha-selineneSeedEssential oil1.25 PercentGC-FID-MSResolve DOI
DamascenineSeedSolvent extraction≤ 13.21 PercentGC-FID-MSResolve DOI
DamascenineSeedSolvent extraction≥ 1.2 PercentGC-FID-MSResolve DOI
DamascenineSeedEssential oil4.49 PercentGC-FID-MSResolve DOI
Naphthalene derivativesSeedSolvent extraction≥ 0.02 PercentGC-FID-MSResolve DOI
Naphthalene derivativesSeedSolvent extraction≤ 0.13 PercentGC-FID-MSResolve DOI
Naphthalene derivativesSeedSolvent extraction≥ 0.01 PercentGC-FID-MSResolve DOI
Naphthalene derivativesSeedSolvent extraction≤ 0.85 PercentGC-FID-MSResolve DOI
AlkaloidsSeedSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
Alpha-selineneSeedEssential oil3.5 PercentGC-MSNo resolvable identifier
Alpha-selineneSeedEssential oil7.8 PercentGC-MS (Q)No resolvable identifier
Alpha-selineneSeedSolvent extraction6.5 PercentGC-MS (Q)No resolvable identifier
Beta-​selineneSeedEssential oil4.8 PercentGC-MS (Q)No resolvable identifier
Beta-​selineneSeedSolvent extraction7.2 PercentGC-MS (Q)No resolvable identifier
DamascenineSeedSolvent extraction0.32 PercentTraditional analytical techniques (wet chemical tests)No resolvable identifier
DamascenineSeedEssential oil3.2 PercentGC-MSNo resolvable identifier
Diterpene estersSeedSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Sajfrtova, Marie., Sovova, Helena., Karban, Jindrich. Enrichment of Nigella damascena extract with volatile compounds using supercritical fluid extraction . Journal of supercritical fluids, 2014, vol. 94, p. 160-164. DOI
  2. Ogawa, Keiko., Nakamura, Seikou., Asada, Yumiko., Yamashita, Masayuki., Matsuda, Hisashi. Oxazonigelladine and dolabellane-type diterpene constituents from Nigella damascena seeds. Tetrahedron, 2017, p. Ahead of Print.
  3. Ewins, Arthur J. Constitution and Synthesis of Damascenine, the Alkaloid of Nigella damascena. Proc. chem soc., 1912, vol. 28, p. 38.
  4. Fico, G., Bader, A., Flamini, G., Cioni, PL., Morelli, L. Essential oil of Niagella damascena L. (Ranunculaceae) seeds. Journal of essential oil research, 2003, vol. 15, no. 1, p. 57-58.
  5. Rchid, H., Nmila, R., Bessiere, JM., Sauvaire, Y., Chokairi, M. Volatile components of Nigella damascena L. and Nigella sativa L. seeds. Journal of essential oil research, 2004, vol. 16, no. 6, p. 585-587.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue