Botanical species · safety record
Nigella damascena
The EFSA Compendium of Botanicals holds 19 constituent measurements for Nigella damascena. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Nigella damascena L.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Alpha-selinene6
- Damascenine5
- Naphthalene derivatives4
- Beta-selinene2
- Alkaloids1
- Diterpene esters1
Plant parts
- Seed19
Preparations
- Solvent extraction13
- Essential oil6
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alpha-selinene | Seed | Solvent extraction | ≤ 0.55 Percent | GC-FID-MS | Resolve DOI |
| Alpha-selinene | Seed | Solvent extraction | ≥ 0.05 Percent | GC-FID-MS | Resolve DOI |
| Alpha-selinene | Seed | Essential oil | 1.25 Percent | GC-FID-MS | Resolve DOI |
| Damascenine | Seed | Solvent extraction | ≤ 13.21 Percent | GC-FID-MS | Resolve DOI |
| Damascenine | Seed | Solvent extraction | ≥ 1.2 Percent | GC-FID-MS | Resolve DOI |
| Damascenine | Seed | Essential oil | 4.49 Percent | GC-FID-MS | Resolve DOI |
| Naphthalene derivatives | Seed | Solvent extraction | ≥ 0.02 Percent | GC-FID-MS | Resolve DOI |
| Naphthalene derivatives | Seed | Solvent extraction | ≤ 0.13 Percent | GC-FID-MS | Resolve DOI |
| Naphthalene derivatives | Seed | Solvent extraction | ≥ 0.01 Percent | GC-FID-MS | Resolve DOI |
| Naphthalene derivatives | Seed | Solvent extraction | ≤ 0.85 Percent | GC-FID-MS | Resolve DOI |
| Alkaloids | Seed | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Alpha-selinene | Seed | Essential oil | 3.5 Percent | GC-MS | No resolvable identifier |
| Alpha-selinene | Seed | Essential oil | 7.8 Percent | GC-MS (Q) | No resolvable identifier |
| Alpha-selinene | Seed | Solvent extraction | 6.5 Percent | GC-MS (Q) | No resolvable identifier |
| Beta-selinene | Seed | Essential oil | 4.8 Percent | GC-MS (Q) | No resolvable identifier |
| Beta-selinene | Seed | Solvent extraction | 7.2 Percent | GC-MS (Q) | No resolvable identifier |
| Damascenine | Seed | Solvent extraction | 0.32 Percent | Traditional analytical techniques (wet chemical tests) | No resolvable identifier |
| Damascenine | Seed | Essential oil | 3.2 Percent | GC-MS | No resolvable identifier |
| Diterpene esters | Seed | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Sajfrtova, Marie., Sovova, Helena., Karban, Jindrich. Enrichment of Nigella damascena extract with volatile compounds using supercritical fluid extraction . Journal of supercritical fluids, 2014, vol. 94, p. 160-164. DOI
- Ogawa, Keiko., Nakamura, Seikou., Asada, Yumiko., Yamashita, Masayuki., Matsuda, Hisashi. Oxazonigelladine and dolabellane-type diterpene constituents from Nigella damascena seeds. Tetrahedron, 2017, p. Ahead of Print.
- Ewins, Arthur J. Constitution and Synthesis of Damascenine, the Alkaloid of Nigella damascena. Proc. chem soc., 1912, vol. 28, p. 38.
- Fico, G., Bader, A., Flamini, G., Cioni, PL., Morelli, L. Essential oil of Niagella damascena L. (Ranunculaceae) seeds. Journal of essential oil research, 2003, vol. 15, no. 1, p. 57-58.
- Rchid, H., Nmila, R., Bessiere, JM., Sauvaire, Y., Chokairi, M. Volatile components of Nigella damascena L. and Nigella sativa L. seeds. Journal of essential oil research, 2004, vol. 16, no. 6, p. 585-587.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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