Botanical species · safety record

Notopterygium incisum

The EFSA Compendium of Botanicals holds 15 constituent measurements and 2 adverse-effect records for Notopterygium incisum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Notopterygium incisum K.C.Ting ex H.T.Chang

15Constituent measurements

2Safety records

7Cited sources

48Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 48 licensed products naming Notopterygium incisum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Extract Type TBA

Source material stated

Dried rhizome
Dried root(s)
New material
Radix
Rhizoma
Rhizome
Rhizome Extract
Rhizome and root(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Bergapten	Roots and other underground parts	Solvent extraction	≤ 0.075 Gram/100 gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Bergapten	Roots and other underground parts	Solvent extraction	≥ 0.019 Gram/100 gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Bergapten	Roots and other underground parts	Solvent extraction	8e-04 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Furanocoumarins	Stem / stalk	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Isoimperatorin	Roots and other underground parts	Solvent extraction	0.11 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Isoimperatorin	Roots and other underground parts	Solvent extraction	≤ 0.82 Gram/100 gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Isoimperatorin	Roots and other underground parts	Solvent extraction	≥ 1.31 Milligram/gram	HPLC-DAD	Resolve DOI
Isoimperatorin	Roots and other underground parts	Solvent extraction	≥ 0.22 Gram/100 gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Isoimperatorin	Roots and other underground parts	Solvent extraction	≤ 7 Milligram/gram	HPLC-DAD	Resolve DOI
Notopterol	Roots and other underground parts	Solvent extraction	≥ 11.22 Milligram/gram	HPLC-DAD	Resolve DOI
Notopterol	Roots and other underground parts	Solvent extraction	≤ 15.56 Milligram/gram	HPLC-DAD	Resolve DOI
Notopterol	Roots and other underground parts	Solvent extraction	≥ 0.26 Gram/100 gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Notopterol	Roots and other underground parts	Solvent extraction	≤ 1.24 Gram/100 gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Polyacetylene derivatives	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Immunotoxicity	—	Roots and other underground parts	—	—	Other	Resolve DOI
Immunotoxicity	—	Roots and other underground parts	—	—	Other	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Matsuda, H., Hirata, N., Kawaguchi, Y., Yamazaki, M., Naruto, S., Shibano, M., Masahiko, TI., Baba, K., Kubo, M. Melanogenesis stimulation in murine B16 melanoma cells by Umberiferae plant extracts and their coumarin constituents. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2005, vol. 28, no. 7, p. 1229-1233. DOI
Qian, Guang-Sheng., Wang, Qing., Leung, Kelvin Sze-Yin., Qin, Yong., Zhao, Zhongzhen., Jiang, Zhi-Hong. Quality assessment of Rhizoma et Radix Notopterygii by HPTLC and HPLC fingerprinting and HPLC quantitative analysis . Journal of pharmaceutical and biomedical analysis, 2007, vol. 44, no. 3, p. 812-817. DOI
Liu, Xin., Jiang, Shunyuan., Xu, Kaijie., Sun, Hui., Zhou, Yi., Xu, Xuemin., Yi, Jinhai., Gu, Yucheng., Ding, Lisheng S. Quantitative analysis of chemical constituents in different commercial parts of Notopterygium incisum by HPLC-DAD-MS. JOURNAL OF ETHNOPHARMACOLOGY, 2009, vol. 126, no. 3, p. 474-479. DOI
Atanasov, Atanas G., Blunder, Martina., Fakhrudin, Nanang., Liu, Xin., Noha, Stefan M., Malainer, Clemens., Kramer, Matthias P., Cocic, Amina., Kunert, Olaf., Schinkovitz, Andreas., Heiss, Elke H., Schuster, Daniela., Dirsch, Verena M., Bauer, Rudolf. Polyacetylenes from Notopterygium incisum-New Selective Partial Agonists of Peroxisome Proliferator-Activated Receptor-Gamma . Plos one, 2013, vol. 8, no. 4. DOI
Wu, Shi-Biao., Zhao, Yun., Fan, Hui., Hu, Ying-He., Hamann, Mark T., Peng, Jiang-Nan., Starks, Courtney M., O'Neil-Johnson, Mark., Hu, Jin-Feng. New Guaiane Sesquiterpenes and Furanocoumarins from Notopterygium incisum. PLANTA MEDICA, 2008, vol. 74, no. 15, p. 1812-1817. DOI
Xu, K., Jiang, S., Sun, H., Zhou, Y., Xu, X., Peng, S., Ding, L. New alkaloids from the seeds of Notopterygium incisum. NATURAL PRODUCT RESEARCH, 2012, vol. 26, no. 20, p. 1898-1903. DOI
Zhou, J., Ouedraogo, M., Qu, F., Duez, P. Potential genotoxicity of traditional Chinese medicinal plants and phytochemicals: An overview. Phytotherapy Research, 2013, vol. 27, no. 12, p. 1745-1755. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature