Botanical species · safety record

Oenanthe crocata

The EFSA Compendium of Botanicals holds 4 constituent measurements and 18 adverse-effect records for Oenanthe crocata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Oenanthe crocata L.

4Constituent measurements
18Safety records
9Cited sources
10Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 10 licensed products naming Oenanthe crocata as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Rhizome
  • Root

What the records describe

Constituents measured

  • Oenanthotoxin4

Plant parts

  • Roots and other underground parts16
  • Unspecified2

Preparations

  • Solvent extraction3
  • Thermal treatment (heating for preservation)1

Effect types

  • Neurotoxicity11
  • Systemic4
  • Digestive2
  • Other toxicities1

Target tissues

  • Neurologic9
  • Neurologic: central nervous system3
  • Digestive2
  • Heart1
  • Spinal cord1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
OenanthotoxinRoots and other underground partsSolvent extractionHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
OenanthotoxinRoots and other underground partsUnspecifiedResolve DOI
OenanthotoxinRoots and other underground partsSolvent extractionHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
OenanthotoxinRoots and other underground partsSolvent extraction0.06 PercentChromatographic testsNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DigestiveDigestiveRoots and other underground partsHuman (as organism)Case reportResolve DOI
NeurotoxicityNeurologicRoots and other underground partsHorse (as animal)Case reportResolve DOI
NeurotoxicityNeurologicRoots and other underground partsCase reportResolve DOI
NeurotoxicityNeurologicRoots and other underground partsCase reportResolve DOI
NeurotoxicitySpinal cordRoots and other underground partsHuman (as organism)Case reportResolve DOI
NeurotoxicityNeurologicRoots and other underground partsHuman (as organism)Case reportResolve DOI
NeurotoxicityNeurologicRoots and other underground partsHorse (as animal)Case reportResolve DOI
NeurotoxicityNeurologicUnspecifiedHuman (as organism)Case reportResolve DOI
SystemicNeurologicUnspecifiedHuman (as organism)Case reportResolve DOI
SystemicNeurologic: central nervous systemRoots and other underground partsHuman (as organism)Case reportResolve DOI
SystemicNeurologic: central nervous systemRoots and other underground partsCase reportResolve DOI
DigestiveDigestiveHuman (as organism)Case reportNo resolvable identifier
NeurotoxicityHeartHuman (as organism)Case reportNo resolvable identifier
NeurotoxicityNeurologicHuman (as organism)Case reportNo resolvable identifier
NeurotoxicityNeurologicHuman (as organism)Case reportNo resolvable identifier
NeurotoxicityNeurologic: central nervous systemRoots and other underground partsThermal treatment (heating for preservation)Human (as organism)Case reportNo resolvable identifier
Other toxicitiesRoots and other underground partsHuman (as organism)Case reportNo resolvable identifier
SystemicRoots and other underground partsCase reportNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Anonymous. An Account of the Poisonous Effects of the Oenanthe Crocata, or Hemlock Dropwort. The london medical journal, 1784, vol. 5, no. 2, p. 192-199.
  2. Durand, M. -F., Pommier, P., Chazalette, A., de Haro, L. Child poisoning after ingestion of a wild apiaceae: A case report. Archives de pediatrie, 2008, vol. 15, no. 2, p. 139-141. DOI
  3. Fitzgerald, P., Moss, N., O'Mahony, S., Whelton, M.J. Accidental hemlock poisoning. British medical journal (clinical research ed.), 1987, vol. 295, no. 6613, p. 1657. DOI
  4. JaspersenSchib, R., Theus, L., GuirguisOeschger, M., Gossweiler, B., MeierAbt, PJ. Acute poisonings with toxic giants in Switzerland between 1966 and 1994. Schweizerische medizinische wochenschrift, 1996, vol. 126, no. 25, p. 1085-1098.
  5. KING, LA., LEWIS, MJ., PARRY, D., TWITCHETT, PJ., KILNER, EA. IDENTIFICATION OF OENANTHOTOXIN AND RELATED-COMPOUNDS IN HEMLOCK WATER DROPWORT POISONING . Human toxicology, 1985, vol. 4, no. 4, p. 355-364.
  6. Kite, Geoffrey C., Stoneham, Charlotte A., Veitch, Nigel C., Stein, Bridget K., Whitwell, Katherine E. Application of liquid chromatography-mass spectrometry to the investigation of poisoning by Oenanthe crocata . Journal of chromatography b-analytical technologies in the biomedical and life sciences, 2006, vol. 838, no. 1, p. 63-70. DOI
  7. McGrath, J. Notes on a case of poisoning by oenanthe crocata (Water dropwort). Irish journal of medical science, 1937, vol. 12, no. 7, p. 309-311. DOI
  8. MITCHELL, MI., ROUTLEDGE, PA. HEMLOCK WATER DROPWORT POISONING - REVIEW. Clinical toxicology, 1978, vol. 12, no. 4, p. 417-426.
  9. Schep, Leo J., Slaughter, Robin J., Becket, Gordon., Beasley, D. Michael G. Poisoning due to water hemlock. Clinical toxicology, 2009, vol. 47, no. 4, p. 270-278. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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