Botanical species · safety record
Oenanthe crocata
The EFSA Compendium of Botanicals holds 4 constituent measurements and 18 adverse-effect records for Oenanthe crocata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Oenanthe crocata L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 10 licensed products naming Oenanthe crocata as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- Oenanthotoxin4
Plant parts
- Roots and other underground parts16
- Unspecified2
Preparations
- Solvent extraction3
- Thermal treatment (heating for preservation)1
Effect types
- Neurotoxicity11
- Systemic4
- Digestive2
- Other toxicities1
Target tissues
- Neurologic9
- Neurologic: central nervous system3
- Digestive2
- Heart1
- Spinal cord1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Oenanthotoxin | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Oenanthotoxin | Roots and other underground parts | — | — | Unspecified | Resolve DOI |
| Oenanthotoxin | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Oenanthotoxin | Roots and other underground parts | Solvent extraction | 0.06 Percent | Chromatographic tests | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Digestive | Digestive | Roots and other underground parts | — | Human (as organism) | Case report | Resolve DOI |
| Neurotoxicity | Neurologic | Roots and other underground parts | — | Horse (as animal) | Case report | Resolve DOI |
| Neurotoxicity | Neurologic | Roots and other underground parts | — | — | Case report | Resolve DOI |
| Neurotoxicity | Neurologic | Roots and other underground parts | — | — | Case report | Resolve DOI |
| Neurotoxicity | Spinal cord | Roots and other underground parts | — | Human (as organism) | Case report | Resolve DOI |
| Neurotoxicity | Neurologic | Roots and other underground parts | — | Human (as organism) | Case report | Resolve DOI |
| Neurotoxicity | Neurologic | Roots and other underground parts | — | Horse (as animal) | Case report | Resolve DOI |
| Neurotoxicity | Neurologic | Unspecified | — | Human (as organism) | Case report | Resolve DOI |
| Systemic | Neurologic | Unspecified | — | Human (as organism) | Case report | Resolve DOI |
| Systemic | Neurologic: central nervous system | Roots and other underground parts | — | Human (as organism) | Case report | Resolve DOI |
| Systemic | Neurologic: central nervous system | Roots and other underground parts | — | — | Case report | Resolve DOI |
| Digestive | Digestive | — | — | Human (as organism) | Case report | No resolvable identifier |
| Neurotoxicity | Heart | — | — | Human (as organism) | Case report | No resolvable identifier |
| Neurotoxicity | Neurologic | — | — | Human (as organism) | Case report | No resolvable identifier |
| Neurotoxicity | Neurologic | — | — | Human (as organism) | Case report | No resolvable identifier |
| Neurotoxicity | Neurologic: central nervous system | Roots and other underground parts | Thermal treatment (heating for preservation) | Human (as organism) | Case report | No resolvable identifier |
| Other toxicities | — | Roots and other underground parts | — | Human (as organism) | Case report | No resolvable identifier |
| Systemic | — | Roots and other underground parts | — | — | Case report | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Anonymous. An Account of the Poisonous Effects of the Oenanthe Crocata, or Hemlock Dropwort. The london medical journal, 1784, vol. 5, no. 2, p. 192-199.
- Durand, M. -F., Pommier, P., Chazalette, A., de Haro, L. Child poisoning after ingestion of a wild apiaceae: A case report. Archives de pediatrie, 2008, vol. 15, no. 2, p. 139-141. DOI
- Fitzgerald, P., Moss, N., O'Mahony, S., Whelton, M.J. Accidental hemlock poisoning. British medical journal (clinical research ed.), 1987, vol. 295, no. 6613, p. 1657. DOI
- JaspersenSchib, R., Theus, L., GuirguisOeschger, M., Gossweiler, B., MeierAbt, PJ. Acute poisonings with toxic giants in Switzerland between 1966 and 1994. Schweizerische medizinische wochenschrift, 1996, vol. 126, no. 25, p. 1085-1098.
- KING, LA., LEWIS, MJ., PARRY, D., TWITCHETT, PJ., KILNER, EA. IDENTIFICATION OF OENANTHOTOXIN AND RELATED-COMPOUNDS IN HEMLOCK WATER DROPWORT POISONING . Human toxicology, 1985, vol. 4, no. 4, p. 355-364.
- Kite, Geoffrey C., Stoneham, Charlotte A., Veitch, Nigel C., Stein, Bridget K., Whitwell, Katherine E. Application of liquid chromatography-mass spectrometry to the investigation of poisoning by Oenanthe crocata . Journal of chromatography b-analytical technologies in the biomedical and life sciences, 2006, vol. 838, no. 1, p. 63-70. DOI
- McGrath, J. Notes on a case of poisoning by oenanthe crocata (Water dropwort). Irish journal of medical science, 1937, vol. 12, no. 7, p. 309-311. DOI
- MITCHELL, MI., ROUTLEDGE, PA. HEMLOCK WATER DROPWORT POISONING - REVIEW. Clinical toxicology, 1978, vol. 12, no. 4, p. 417-426.
- Schep, Leo J., Slaughter, Robin J., Becket, Gordon., Beasley, D. Michael G. Poisoning due to water hemlock. Clinical toxicology, 2009, vol. 47, no. 4, p. 270-278. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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