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Botanical species · safety record

Ononis spinosa

The EFSA Compendium of Botanicals holds 19 constituent measurements for Ononis spinosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Ononis spinosa L.

19Constituent measurements
0Safety records
10Cited sources
23Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 23 licensed products naming Ononis spinosa as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry

Source material stated

  • Aerial parts
  • Fresh aerial part collected at flowering time
  • Parties aériennes fraîches récoltées au moment de la floraison
  • Plante entière
  • Root
  • Whole plant
  • Whole plant(s)

What the records describe

Constituents measured

  • Isoflavones3
  • Biochanin-a2
  • Formononetin2
  • Genistein2
  • Scopoletin2
  • Camphor1
  • Carvone1
  • Estragole1
  • Lectins1
  • Menthone1

Plant parts

  • Roots and other underground parts15
  • Leaves2
  • Unspecified2

Preparations

  • Solvent extraction14
  • Essential oil5

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Biochanin-aRoots and other underground partsSolvent extraction≤ 0.22 Milligram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Biochanin-aRoots and other underground partsSolvent extraction≥ 0.06 Milligram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
FormononetinRoots and other underground partsSolvent extraction≤ 6.3 Milligram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
FormononetinRoots and other underground partsSolvent extraction≥ 3.1 Milligram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
GenisteinRoots and other underground partsSolvent extraction≥ 0.3 Milligram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
GenisteinRoots and other underground partsSolvent extraction≤ 6.6 Milligram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
IsoflavonesRoots and other underground partsSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
IsoflavonesUnspecifiedSolvent extraction—HPLC-UVResolve DOI
IsoflavonesRoots and other underground partsSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
LectinsRoots and other underground partsSolvent extraction45 Milligram/kilogramChromatographic testsResolve DOI
ScopoletinLeavesSolvent extraction≤ 44 Microgram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
ScopoletinLeavesSolvent extraction≥ 2.3 Microgram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
CamphorRoots and other underground partsEssential oil—GC-MSNo resolvable identifier
CarvoneRoots and other underground partsEssential oil—GC-MSNo resolvable identifier
EstragoleRoots and other underground partsEssential oil—GC-MSNo resolvable identifier
MenthoneRoots and other underground partsEssential oil—GC-MSNo resolvable identifier
Naphthalene derivativesRoots and other underground partsEssential oil—Gaschromatography (GC)No resolvable identifier
PterocarpansUnspecifiedSolvent extraction—UnspecifiedNo resolvable identifier
Triterpene saponinsRoots and other underground partsSolvent extraction—Nuclear Magnetic Resonance (NMR)No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Klejdus, B., Vacek, J., Lojkova, L., Benesova, L., Kuban, V. Ultrahigh-pressure liquid chromatography of isoflavones and phenolic acids on different stationary phases . Journal of chromatography a, 2008, vol. 1195, no. 1-2, p. 52-59. DOI
  2. Shaker, KH., Dockendorff, K., Bernhardt, M., Seifert, K. A new triterpenoid saponin from Ononis spinosa and two new flavonoid glycosides from Ononis vaginalis. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2004, vol. 59, no. 1, p. 124-128.
  3. Bajerova, Petra., Adam, Martin., Bajer, Tomas., Ventura, Karel. Comparison of various techniques for the extraction and determination of antioxidants in plants. JOURNAL OF SEPARATION SCIENCE, 2014, vol. 37, no. 7, p. 835-844. DOI
  4. Fujise, Yutaka., Toda, Takashi., Ito, Sho. Isolation of trifolirhizin from Ononis spinosa. Chemical pharmaceutical bulletin, 1965, p. 93-95.
  5. Hesse, Carmen., Hilp, Karin., Kating, Horst., Schaden, Gerhard. Constituents of Ononis spinosa L., part 2. Aromatic hydrocarbons in the essential oils of Radix and Herba Ononidis. Archiv der pharmazie (weinheim, germany), 1977, p. 792-795.
  6. Hilp, K., Kating, H., Schaden, G. Constituents of Ononis spinosa. 1. Essential oil of the radix ononidis. Archiv der pharmazie (weinheim, germany), 1975, p. 429-433.
  7. HOREJSI, V., KOCOUREK, J. STUDIES ON LECTINS .36. PROPERTIES OF SOME LECTINS PREPARED BY AFFINITY CHROMATOGRAPHY ON O-GLYCOSYL POLYACRYLAMIDE GELS. BIOCHIMICA ET BIOPHYSICA ACTA, 1978, vol. 538, no. 2, p. 299-315. DOI
  8. Klejdus, B., Vacek, J., Benesova, L., Kopecky, J., Lapcik, O., Kuban, V. Rapid-resolution HPLC with spectrometric detection for the determination and identification of isoflavones in soy preparations and plant extracts . Analytical and bioanalytical chemistry, 2007, vol. 389, no. 7-8, p. 2277-2285. DOI
  9. KOSTER, J., STRACK, D., BARZ, W. HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF ISOFLAVONES AND STRUCTURAL ELUCIDATION OF ISOFLAVONE 7-O-GLUCOSIDE 6''-MALONATES FROM CICER-ARIETINUM . Planta medica, 1983, vol. 48, no. 3, p. 131-135. DOI
  10. PIETTA, P., CALATRONI, A., ZIO, C. HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF FLAVONOIDS FROM ONONIS-SPINOSA L . Journal of chromatography, 1983, vol. 280, no. 1, p. 172-175. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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