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Botanical species · safety record

Onopordum acanthium

The EFSA Compendium of Botanicals holds 9 constituent measurements for Onopordum acanthium. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Onopordum acanthium L.

9Constituent measurements
0Safety records
8Cited sources
3Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 3 licensed products naming Onopordum acanthium as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Flower

What the records describe

Constituents measured

  • Sesquiterpene lactones3
  • Coumarins1
  • Epoxides1
  • Furan derivatives1
  • Lignans1
  • Phenylpropanoids1
  • Tannins1

Plant parts

  • Aerial part of plants2
  • Leaves2
  • Seed2
  • Unspecified2
  • Fruit unspecified1

Preparations

  • Solvent extraction6

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
EpoxidesSeed——Standard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
LignansAerial part of plantsSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
PhenylpropanoidsSeedSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
Sesquiterpene lactonesAerial part of plantsSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
Sesquiterpene lactonesLeavesSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
CoumarinsUnspecified——UnspecifiedNo resolvable identifier
Furan derivativesFruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Sesquiterpene lactonesLeavesSolvent extraction—Nuclear Magnetic Resonance (NMR)No resolvable identifier
TanninsUnspecified——UnspecifiedNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Lajter I., Pan SP., Nikles S., Ortmann S., Vasas A., Csupor-Loffler B., Forgo P., Hohmann J., Bauer R. Inhibition of COX-2 and NF-kappaB1 Gene Expression, NO Production, 5-LOX, andCOX-1 and COX-2 Enzymes by Extracts and Constituents of Onopordum acanthium.. Planta medica, 2015, vol. 81, no. 14, p. 1270-6. DOI
  2. Drozdz, B., Holub, M., Samek, Z., Herout, V., Sorm, F. Terpenes. CXCII. The constitution and absolute configuration of onopordopicrine, a sesquiterpenic lactone from Onopordon acanthium. Collection of czechoslovak chemical communications, 1968, p. 1730-1737.
  3. Tyumkina, T. V., Nuriev, I. F., Khalilov, L. M., Akhmetova, V. R., Dzhemilev, U. M. PMR and (13)C NMR spectra of biologically active compounds. XIII.* Structure and stereochemistry of a new phenylpropanoid glycoside isolated from Onopordum acanthium seeds . Chemistry of natural compounds, 2009, vol. 45, no. 1, p. 61-65. DOI
  4. Watanabe, Yusuke., Novaes, Paula., Varela, Rosa M., Molinillo, Jose M. G., Kato-Noguchi, Hisashi., Macias, Francisco A. Phytotoxic Potential of Onopordum acanthium L. (Asteraceae). CHEMISTRY & BIODIVERSITY, 2014, vol. 11, no. 8, p. 1247-1255. DOI
  5. Kang, Ting-Guo., Kawamura, Tomoko., Noro, Yukio., Tanaka, Toshihiro. Pharmacognostical evaluation of Arctii Fructus (2): Adulteration on the Chinese commercial samples. Natural Medicines, 1999, vol. 53, no. 4, p. 206-208.
  6. Bogs, H. U., Bogs, U. Constituents of Onopordum acanthium. I. Coumarins and flavones. Pharmazie, 1965, p. 706-709.
  7. Bogs, Hans U., Bogs, Ulrich. Constituents of Onopordum acanthium. II. Flavonoids, tannins, and betaines. Pharmazie, 1967, p. 54-58.
  8. Ul'chenko, N.T., Gusakova, S.D., Glushenkova, A.I. Oxygenated acids of the lipids of Onopordum acanthium seeds. Chemistry of natural compounds, 1993, vol. 29, no. 4, p. 447-450. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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