Botanical species · safety record
Packera aurea
The EFSA Compendium of Botanicals holds 3 constituent measurements and 1 adverse-effect record for Packera aurea. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Packera aurea (L.) Á.Löve & D.Löve
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Alkaloids1
- Otosenine1
- Sesquiterpene alkaloids1
Plant parts
- Live plants2
- Aerial part of plants1
- Unspecified1
Preparations
- Solvent extraction4
Effect types
- Hepatotoxicity1
Target tissues
- Liver1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Otosenine | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Sesquiterpene alkaloids | Live plants | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Alkaloids | Unspecified | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Hepatotoxicity | Liver | Live plants | Solvent extraction | Rat (as animal) | Short-term toxicity | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Osuigwe, M.J., Margret, N. Evaluation of the toxicological effects of Senecio aureus extract on the liver and hematological parameters in wistar rats. Jordan journal of biological sciences, 2017, vol. 10, no. 1, p. 29-32.
- Kelly, Edgar A., Lynn, E. V. Chemical study of Senecio aureus. Journal of the american pharmaceutical association (1912-1977), 1931, vol. 20, p. 755-9.
- RESCH, JF., GOLDSTEIN, SA., MEINWALD, J. OTOSENINE FROM SENECIO-AUREUS. Planta medica, 1983, vol. 47, no. 4, p. 255-255. DOI
- NACHMAN, RJ. TETRAHYDROLIGULARENOLIDE AND RELATED EREMOPHILANES FROM SENECIO-AUREUS. Phytochemistry, 1983, vol. 22, no. 3, p. 780-782. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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