Botanical species · safety record

Papaver rhoeas

The EFSA Compendium of Botanicals holds 6 constituent measurements and 3 adverse-effect records for Papaver rhoeas. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Papaver rhoeas L.

6Constituent measurements
3Safety records
5Cited sources
11Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 11 licensed products naming Papaver rhoeas as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry

Source material stated

  • Flower
  • Flowers
  • Petal

What the records describe

Constituents measured

  • Alkaloids2
  • Rhoeadine2
  • Coptisine1
  • Isorheagenine1

Plant parts

  • Live plants3
  • Roots and other underground parts2
  • Unspecified2
  • Aerial part of plants1
  • Seed1

Preparations

  • Solvent extraction6
  • Thermal treatment (heating for preservation)2

Effect types

  • Neurotoxicity2
  • Hepatotoxicity1

Target tissues

  • Neurologic: central nervous system2
  • Liver1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsAerial part of plantsSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
AlkaloidsLive plantsSolvent extraction0.046 PercentIR and Raman SpectroscopyNo resolvable identifier
CoptisineLive plantsSolvent extraction0.004 PercentIR and Raman SpectroscopyNo resolvable identifier
IsorheagenineRoots and other underground partsSolvent extraction0.024 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
RhoeadineRoots and other underground partsSolvent extraction0.027 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
RhoeadineLive plantsSolvent extraction0.027 PercentIR and Raman SpectroscopyNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
NeurotoxicityNeurologic: central nervous systemUnspecifiedThermal treatment (heating for preservation)Human (as organism)Case reportResolve DOI
NeurotoxicityNeurologic: central nervous systemUnspecifiedThermal treatment (heating for preservation)Human (as organism)Case reportResolve DOI
HepatotoxicityLiverSeedHuman (as organism)Case reportNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Slavik, Jiri. Alkaloids of the Papaveraceae. Part LXVI. Characterization of alkaloids from the roots of Papaver rhoeas L. Collection of Czechoslovak Chemical Communications, 1978, p. 316-319.
  2. Sariyar, Gunay., Mat, Afife., Unsal, Caglayan., Ozhatay, Neriman. Biodiversity in the alkaloids of annual Papaver species of Turkish origin. Acta pharmaceutica turcica, 2002, p. 159-168.
  3. Gonullu, Hayriye., Karadas, Sevdegul., Dulger, Ahmet Cumhur., Ebinc, Senar. Hepatotoxicity associated with the ingestion of Papaver Rhoease. JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION, 2014, vol. 64, no. 10, p. 1189-1190.
  4. Gunaydin, Yahya Kemal., Dundar, Zerrin Defne., Cekmen, Bora., Akilli, Nazire Belgin., Koylu, Ramazan., Cander, Basar. Intoxication due to Papaver rhoeas (Corn Poppy): Five Case Reports.. Case reports in medicine, 2015, vol. 2015, p. 321360-321360. DOI
  5. Slavik, Jiri., Slavikova, Leonora., Bochorakova, Jitka. Alkaloids of the Papaveraceae. Part LXXXVIII. Alkaloids from Papaver rhoeas var. chelidonioides O. Kuntze, P. confine Jord., and P. dubium L. Collection of Czechoslovak Chemical Communications, 1989, p. 1118-1125.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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