Botanical species · safety record
Papaver rhoeas
The EFSA Compendium of Botanicals holds 6 constituent measurements and 3 adverse-effect records for Papaver rhoeas. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Papaver rhoeas L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 11 licensed products naming Papaver rhoeas as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Alkaloids2
- Rhoeadine2
- Coptisine1
- Isorheagenine1
Plant parts
- Live plants3
- Roots and other underground parts2
- Unspecified2
- Aerial part of plants1
- Seed1
Preparations
- Solvent extraction6
- Thermal treatment (heating for preservation)2
Effect types
- Neurotoxicity2
- Hepatotoxicity1
Target tissues
- Neurologic: central nervous system2
- Liver1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Aerial part of plants | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Alkaloids | Live plants | Solvent extraction | 0.046 Percent | IR and Raman Spectroscopy | No resolvable identifier |
| Coptisine | Live plants | Solvent extraction | 0.004 Percent | IR and Raman Spectroscopy | No resolvable identifier |
| Isorheagenine | Roots and other underground parts | Solvent extraction | 0.024 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Rhoeadine | Roots and other underground parts | Solvent extraction | 0.027 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Rhoeadine | Live plants | Solvent extraction | 0.027 Percent | IR and Raman Spectroscopy | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Neurotoxicity | Neurologic: central nervous system | Unspecified | Thermal treatment (heating for preservation) | Human (as organism) | Case report | Resolve DOI |
| Neurotoxicity | Neurologic: central nervous system | Unspecified | Thermal treatment (heating for preservation) | Human (as organism) | Case report | Resolve DOI |
| Hepatotoxicity | Liver | Seed | — | Human (as organism) | Case report | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Slavik, Jiri. Alkaloids of the Papaveraceae. Part LXVI. Characterization of alkaloids from the roots of Papaver rhoeas L. Collection of Czechoslovak Chemical Communications, 1978, p. 316-319.
- Sariyar, Gunay., Mat, Afife., Unsal, Caglayan., Ozhatay, Neriman. Biodiversity in the alkaloids of annual Papaver species of Turkish origin. Acta pharmaceutica turcica, 2002, p. 159-168.
- Gonullu, Hayriye., Karadas, Sevdegul., Dulger, Ahmet Cumhur., Ebinc, Senar. Hepatotoxicity associated with the ingestion of Papaver Rhoease. JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION, 2014, vol. 64, no. 10, p. 1189-1190.
- Gunaydin, Yahya Kemal., Dundar, Zerrin Defne., Cekmen, Bora., Akilli, Nazire Belgin., Koylu, Ramazan., Cander, Basar. Intoxication due to Papaver rhoeas (Corn Poppy): Five Case Reports.. Case reports in medicine, 2015, vol. 2015, p. 321360-321360. DOI
- Slavik, Jiri., Slavikova, Leonora., Bochorakova, Jitka. Alkaloids of the Papaveraceae. Part LXXXVIII. Alkaloids from Papaver rhoeas var. chelidonioides O. Kuntze, P. confine Jord., and P. dubium L. Collection of Czechoslovak Chemical Communications, 1989, p. 1118-1125.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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