Botanical species · safety record

Paris quadrifolia

The EFSA Compendium of Botanicals holds 5 constituent measurements and 1 adverse-effect record for Paris quadrifolia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Paris quadrifolia L.

5Constituent measurements

1Safety records

6Cited sources

19Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 19 licensed products naming Paris quadrifolia as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Fresh Flowering Plant
Plante entière
Whole flowering plant(s)
Whole fresh plants collected when fruits have ripened
Whole plant in flower
Whole plant(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Saponins	Roots and other underground parts	Solvent extraction	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Steroidal saponins	Roots and other underground parts	Solvent extraction	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Lectins	Roots and other underground parts	—	—	Unspecified	No resolvable identifier
Pennogenin tetraglycoside	Live plants	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Steroidal saponins	Live plants	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Heart	Fruit unspecified	—	—	Other	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

NOHARA, T., ITO, Y., SEIKE, H., KOMORI, T., MORIYAMA, M., GOMITA, Y., KAWASAKI, T. STUDY ON THE CONSTITUENTS OF PARIS-QUADRIFORIA L. Chemical & pharmaceutical bulletin, 1982, vol. 30, no. 5, p. 1851-1856.
Stoika, R.S., Antonyuk, V.O., Yakymovych, I.A., Yakymovych, M.Y.A., Korchynsky, O.G., Preobrazhenska, O.V., Stasyk, T.V., Kashtchak, N.I., Lutsik, M.D. Tumor cell response to cytotoxic lectins and heat shock in vitro: Study of possible involvement of transforming growth factor beta1. International journal of medicine, biology and the environment, 2000, vol. 28, no. 1, p. 65-69.
Busser, C. Toxic berries, fruits and pseudo-fruits in traditional medicine and phytotherapy . Phytotherapie (paris), 2007, vol. 5, no. 1, p. 31-36. DOI
Stefanowicz-Hajduk, Justyna., Kawiak, Anna., Gajdus, Jerzy., Ochocka, J. Renata., Paszkiewicz, Monika., Stepnowski, Piotr., Lojkowska, Ewa. CYTOTOXIC ACTIVITY OF PARIS QUADRIFOLIA EXTRACT AND ISOLATED SAPONIN FRACTIONS AGAINST HUMAN TUMOR CELL LINES . Acta biologica cracoviensia series botanica, 2011, vol. 53, no. 2, p. 127-131. DOI
Jenett-Siems, Kristina., Krause, Nadin., Siems, Karsten., Jakupovic, Sven., Wallukat, Gerd., Melzig, Matthias F. Chemical Composition and Biological Activity of Paris quadrifolia L.. Zeitschrift fur naturforschung section c-a journal of biosciences, 2012, vol. 67, no. 11-12, p. 565-570.
Gajdus, Jerzy., Kaczynski, Zbigniew., Kawiak, Anna., Lojkowska, Ewa., Stefanowicz-Hajduk, Justyna., Ochocka, J Renata., Stepnowski, Piotr. Isolation and identification of cytotoxic compounds from the rhizomes of Paris quadrifolia L. . Pharmacognosy magazine, 2014, vol. 10, no. Suppl 2, p. S324-33. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature