Botanical species · safety record

Passiflora edulis

The EFSA Compendium of Botanicals holds 12 constituent measurements and 2 adverse-effect records for Passiflora edulis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Passiflora edulis Sims

12Constituent measurements

2Safety records

4Cited sources

25Licensed products (Canada)

Also recorded as

Passiflora incarnata L.
Passiflora laurifolia L.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 25 licensed products naming Passiflora edulis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Fruit
Seed

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Harman	Unspecified	Solvent extraction	≤ 0.112 Microgram/gram	HPLC-UV	Resolve DOI
Harmine	Unspecified	Solvent extraction	≤ 0.271 Microgram/gram	HPLC-UV	Resolve DOI
Hydrocyanic acid	Fruit unspecified	Fresh	5.7 Milligram/kilogram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Harmalol	Unspecified	Solvent extraction	≥ 745 Nanogram/gram	HPLC with standard detection methods	No resolvable identifier
Harmalol	Unspecified	Solvent extraction	≤ 776 Nanogram/gram	HPLC with standard detection methods	No resolvable identifier
Harman	Unspecified	Solvent extraction	≥ 47.8 Nanogram/gram	HPLC with standard detection methods	No resolvable identifier
Harman	Unspecified	Solvent extraction	≤ 224 Nanogram/gram	HPLC with standard detection methods	No resolvable identifier
Harmine	Unspecified	Solvent extraction	≤ 78.6 Nanogram/gram	HPLC with standard detection methods	No resolvable identifier
Harmol	Unspecified	Solvent extraction	≥ 23.8 Nanogram/gram	HPLC with standard detection methods	No resolvable identifier
Harmol	Unspecified	Solvent extraction	≤ 977 Nanogram/gram	HPLC with standard detection methods	No resolvable identifier
Norharmane	Unspecified	Solvent extraction	≥ 51 Nanogram/gram	HPLC with standard detection methods	No resolvable identifier
Norharmane	Unspecified	Solvent extraction	≤ 81 Nanogram/gram	HPLC with standard detection methods	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Leaves	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier
Nephrotoxicity	Urogenital: kidneys	Leaves	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Rojas, Juan., D�az, David. Evaluaci�n de la toxicidad del extracto metan�lico de hojas de Passiflora edulis Sims (maracuy�), en ratas . Anales de la facultad de medicina, 2009, vol. 70, no. 3, p. 175-180.
Tsuchiya, Hironori., Hayashi, Hideaki., Sato, Masaru., Shimizu, Hiroshi., Iinuma, Munekazu. Quantitative analysis of all types of beta-carboline alkaloids in medicinal plants and dried edible plants by high performance liquid chromatography with selective fluorometric detection. Phytochemical Analysis, 1999, p. 247-253.
Grice, ID., Ferreira, LA., Griffiths, LR. Identification and simultaneous analysis of harmane, harmine, harmol, isovitexin, and vitexin in Passiflora incarnata extracts with a novel HPLC method. JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2001, vol. 24, no. 16, p. 2513-2523. DOI
Cressey, P., Saunders, D., Goodman, J. Cyanogenic glycosides in plant-based foods available in New Zealand. Food additives and contaminants - part a chemistry, analysis, control, exposure and risk assessment, 2013, vol. 30, no. 11, p. 1946-1953. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature