Botanical species · safety record

Petiveria alliacea

The EFSA Compendium of Botanicals holds 5 constituent measurements, 2 adverse-effect records and 1 genotoxicity assay for Petiveria alliacea. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Petiveria alliacea L.

5Constituent measurements

3Safety records

7Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Live plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Asarone	Live plants	Solvent extraction	—	GC-MS	No resolvable identifier
Coumarins	Leaves	Solvent extraction	—	Chromatographic tests	No resolvable identifier
Epoxides	Live plants	Solvent extraction	—	GC-MS	No resolvable identifier
Tannins	Leaves	Solvent extraction	—	Chromatographic tests	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Other toxicities	Neurologic	Aerial part of plants	Solvent extraction	House mouse (as animal)	Other	Resolve DOI
Reproductive	Uterus	Roots and other underground parts	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	gene mutation	sister chromatid exchange assay in mammalian cells	House mouse (as animal)	No data	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Fontoura, M. C. P., Silva, S. do N., Abreu, I. C., Goncalves, J. R. dos S., Borges, M. O. da R., Borges, A. C. R. Effect of Petiveria alliacea L. in the intestinal secretion and motility of rodents. . Revista brasileira de plantas medicinais, 2005, vol. 7, no. 2, p. 37-43.
HOYOS, LS., AU, WW., HEO, MY., MORRIS, DL., LEGATOR, MS. EVALUATION OF THE GENOTOXIC EFFECTS OF A FOLK MEDICINE, PETIVERIA-ALLIACEA (ANAMU). MUTATION RESEARCH, 1992, vol. 280, no. 1, p. 29-34. DOI
Luz DA., Pinheiro AM., da Silva ML., Monteiro MC., Prediger RD., Ferraz Maia CS., Fontes-Junior EA. Ethnobotany, phytochemistry and neuropharmacological effects of Petiveriaalliacea L. (Phytolaccaceae): A review.. Journal of ethnopharmacology, 2016. DOI
Coe, F.G., Parikh, D.M., Johnson, C.A., Anderson, G.J. The good and the bad: Alkaloid screening and brineshrimp bioassays of aqueous extracts of 31 medicinal plants of eastern Nicaragua. Pharmaceutical Biology, 2012, vol. 50, no. 3, p. 384-392. DOI
Sathiyabalan, G., Packia, Lincy M., Muthukumarasamy, S., Mohan, V. R. GC-MS analysis of bioactive components of Petiveria alliacea L. whole plant (phytolaccaceae). International Journal of Pharma Research and Health Sciences, 2014, p. 387-392.
Maia, Carina Scanoni., Teixeira, Valeria Wanderley., Coelho Teixeira, Alvaro Aguiar., Pontes Filho, Nicodemos Teles. Analysis of Fetal and Placental Development in Rats after Administration of Hydroalcoholic Extract from the Root of Petiveria alliacea L. (Phytolaccaceae) . International journal of morphology, 2010, vol. 28, no. 1, p. 165-169.
Blainski, Andressa., Piccolo, Vanessa K., Mello, Joao Carlos P., de Oliveira, Rubia M. W. Dual effects of crude extracts obtained from Petiveria alliacea L. (Phytolaccaceae) on experimental anxiety in mice . Journal of ethnopharmacology, 2010, vol. 128, no. 2, p. 541-544. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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