Botanical species · safety record

Phellodendron chinense

The EFSA Compendium of Botanicals holds 25 constituent measurements for Phellodendron chinense. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Phellodendron chinense C.K.Schneid.

25Constituent measurements
0Safety records
4Cited sources
513Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 513 licensed products naming Phellodendron chinense as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Extract Type TBA
  • decoction

Source material stated

  • Bark
  • Bark (Stir-baked with salt)
  • Bark (carbonized)
  • Bark (dry-fried)
  • Bark (fried with salt)
  • Bark (wine stir-fried)
  • Cortex
  • Cortex extract

What the records describe

Constituents measured

  • Berberine5
  • Jatrorrhizine4
  • Palmatine4
  • Isoquinoline alkaloids3
  • Magnoflorine3
  • Canthin-6-one1
  • Indole alkaloids1
  • Noroxyhydrastinine1
  • Ptelein1
  • Quinoline alkaloids1

Plant parts

  • Bark25

Preparations

  • Solvent extraction25

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
BerberineBarkSolvent extractionUV/VIS spectroscopy (photometry)Resolve DOI
BerberineBarkSolvent extraction5.7 Milligram/gramCapillary (Zone) Electrophoresis (CE or CZE)Resolve DOI
Isoquinoline alkaloidsBarkSolvent extraction1 Milligram/gramCapillary (Zone) Electrophoresis (CE or CZE)Resolve DOI
JatrorrhizineBarkSolvent extraction0.2 Milligram/gramCapillary (Zone) Electrophoresis (CE or CZE)Resolve DOI
JatrorrhizineBarkSolvent extractionUV/VIS spectroscopy (photometry)Resolve DOI
MagnoflorineBarkSolvent extraction5 Milligram/gramCapillary (Zone) Electrophoresis (CE or CZE)Resolve DOI
PalmatineBarkSolvent extraction3.4 Milligram/gramCapillary (Zone) Electrophoresis (CE or CZE)Resolve DOI
PalmatineBarkSolvent extractionUV/VIS spectroscopy (photometry)Resolve DOI
BerberineBarkSolvent extraction≤ 74.25 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
BerberineBarkSolvent extraction≥ 19.06 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
BerberineBarkSolvent extraction610 Microgram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Canthin-6-oneBarkSolvent extraction31 Microgram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Indole alkaloidsBarkSolvent extraction38 Microgram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Isoquinoline alkaloidsBarkSolvent extraction≤ 2.69 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Isoquinoline alkaloidsBarkSolvent extraction≥ 1.53 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
JatrorrhizineBarkSolvent extraction≤ 0.6 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
JatrorrhizineBarkSolvent extraction≥ 0.21 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
MagnoflorineBarkSolvent extraction≤ 6.68 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
MagnoflorineBarkSolvent extraction≥ 1.73 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
NoroxyhydrastinineBarkSolvent extraction44 Microgram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
PalmatineBarkSolvent extraction≤ 0.43 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
PalmatineBarkSolvent extraction≥ 0.13 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
PteleinBarkSolvent extraction21 Microgram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Quinoline alkaloidsBarkSolvent extraction46 Microgram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
SkimmianineBarkSolvent extraction15 Microgram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Xu, Xueqin., Lin, Qiang., He, Xiaoyan., Fu, FengFu., Chen, Guonan. Determination of protoberberine alkaloids in medicinal plants based on acidic potassium permanganate chemiluminescence system. LUMINESCENCE, 2010, vol. 25, no. 5, p. 403-408. DOI
  2. Liu, Y.-M., Sheu, S.-J., Chiou, S.-H., Chang, H.-C., Chen, Y.-P. A comparative study on commercial samples of Phellodendri cortex. Planta Medica, 1993, vol. 59, no. 6, p. 557-561. DOI
  3. Liu, Yong., Chen, Juan., Li, Xue-Hu., Shi, Yan-Ping. Simultaneous Determination of Seven Alkaloids in Phellodendron chinense Schneid by High-Performance Liquid Chromatography . Journal of aoac international, 2010, vol. 93, no. 5, p. 1416-1421.
  4. Zhu, Shuang-lai., Dou, Sheng-shan., Liu, Xin-ru., Liu, Run-hui., Zhang, Wei-dong., Huang, Hong-lin., Zhang, Yi., Hu, Yao-hua., Wang, Shu-ping. Qualitative and quantitative analysis of alkaloids in Cortex Phellodendri by HPLC-ESI-MS/MS and HPLC-DAD. Chemical Research in Chinese Universities, 2011, p. 38-44.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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