Botanical species · safety record

Phyllanthus acidus

The EFSA Compendium of Botanicals holds 3 constituent measurements and 3 adverse-effect records for Phyllanthus acidus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Phyllanthus acidus (L.) Skeels

3Constituent measurements
3Safety records
5Cited sources
1Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Phyllanthus acidus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Fresh

What the records describe

Constituents measured

  • Alkaloids1
  • Furan derivatives1
  • Saponins1

Plant parts

  • Leaves4
  • Aerial part of plants1
  • Roots and other underground parts1

Preparations

  • Solvent extraction6

Effect types

  • Digestive1
  • Nephrotoxicity1
  • Neurotoxicity1

Target tissues

  • Digestive1
  • Neurologic: central nervous system1
  • Urogenital: kidneys1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Furan derivativesRoots and other underground partsSolvent extractionCapillary (Zone) Electrophoresis (CE or CZE)Resolve DOI
AlkaloidsAerial part of plantsSolvent extractionPhytochemical screeningNo resolvable identifier
SaponinsLeavesSolvent extractionPhytochemical screeningNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DigestiveDigestiveLeavesSolvent extractionRat (as animal)Short-term toxicityResolve DOI
NephrotoxicityUrogenital: kidneysLeavesSolvent extractionRat (as animal)OtherNo resolvable identifier
NeurotoxicityNeurologic: central nervous systemLeavesSolvent extractionHouse mouse (as animal)OtherNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Borah, A., Devi, D. Neuropharmacological effects of Phyllanthus acidus in swiss albino mice. Indian journal of pharmacology, 2014, vol. 46, p. S46-S46.
  2. Chongsa, Watchara., Radenahmad, Nisaudah., Jansakul, Chaweewan. Six weeks oral gavage of a Phyllanthus acidus leaf water extract decreased visceral fat, the serum lipid profile and liver lipid accumulation in middle-aged male rats. JOURNAL OF ETHNOPHARMACOLOGY, 2014, vol. 155, no. 1, p. 396-404. DOI
  3. Vikasari, S.N., Sukandar, E.Y., Sutjiatmo, A.B., Riyanti, S. Diuretic effect of the ethanol extracts of phyllanthus acidus l (skeels) leaves in wistar rats. International Journal of Pharmacy and Pharmaceutical Sciences, 2015, vol. 7, no. 1, p. 120-123.
  4. Liliwirianis, N., Musa, Nor Lailatul Wahidah., Zain, Wan Zuraida Wan Mohd., Kassim, Jamaluddin., Karim, Syaikh Abdul. Premilinary Studies on Phytochemical Screening of Ulam and Fruit from Malaysia. E-JOURNAL OF CHEMISTRY, 2011, vol. 8, p. S285-S288.
  5. Durham, DG., Reid, RG., Wangboonskul, J., Daodee, S. Extraction of phyllanthusols A and B from Phyllanthus acidus and analysis by capillary electrophoresis. PHYTOCHEMICAL ANALYSIS, 2002, vol. 13, no. 6, p. 358-362. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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