Botanical species · safety record

Phyllanthus emblica

The EFSA Compendium of Botanicals holds 18 constituent measurements and 2 adverse-effect records for Phyllanthus emblica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Phyllanthus emblica L.

18Constituent measurements
2Safety records
6Cited sources
726Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 726 licensed products naming Phyllanthus emblica as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Extract Type TBA
  • Fresh
  • fluid

Source material stated

  • Aged bark
  • Amla fruit extract
  • Berry/Berries
  • Fruit
  • Fruit (standardized extract)
  • Fruit extract
  • Fruit flesh
  • Fruit pericarp

What the records describe

Constituents measured

  • Ellagitannins (hydrolysable tannins)4
  • Beta-glucogallin2
  • Gallic acid2
  • Glucosinolates2
  • Sinigrin2
  • Alkaloids1
  • Chebulagic acid1
  • Corilagin1
  • Coumarins1
  • Piperine1

Plant parts

  • Fruit unspecified12
  • Seed4
  • Leaves2
  • Stem2
  • stalk2

Preparations

  • Solvent extraction20

Effect types

  • Digestive2

Target tissues

  • Digestive2

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsFruit unspecifiedSolvent extractionPhytochemical screeningResolve DOI
Chebulagic acidFruit unspecifiedSolvent extractionResolve DOI
CorilaginFruit unspecifiedSolvent extractionResolve DOI
CoumarinsFruit unspecifiedSolvent extractionPhytochemical screeningResolve DOI
Ellagitannins (hydrolysable tannins)Fruit unspecifiedSolvent extractionResolve DOI
Ellagitannins (hydrolysable tannins)Fruit unspecifiedSolvent extractionLC-MSResolve DOI
Gallic acidFruit unspecifiedSolvent extractionResolve DOI
GlucosinolatesSeedSolvent extraction≤ 56.598 Millimole/kilogramHPLC-UVResolve DOI
GlucosinolatesSeedSolvent extraction≥ 59.918 Millimole/kilogramHPLC-UVResolve DOI
SaponinsFruit unspecifiedSolvent extractionPhytochemical screeningResolve DOI
SinigrinSeedSolvent extraction≤ 35.927 Millimole/kilogramHPLC-UVResolve DOI
SinigrinSeedSolvent extraction≥ 36.147 Millimole/kilogramHPLC-UVResolve DOI
Beta-glucogallinStem / stalkSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Beta-glucogallinLeavesSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Ellagitannins (hydrolysable tannins)Stem / stalkSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Ellagitannins (hydrolysable tannins)LeavesSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Gallic acidFruit unspecifiedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
PiperineFruit unspecifiedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DigestiveDigestiveFruit unspecifiedSolvent extractionHouse mouse (as animal)Acute toxicityResolve DOI
DigestiveDigestiveFruit unspecifiedSolvent extractionHouse mouse (as animal)Acute toxicityResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Hu, Ye., Liang, Hao., Yuan, Qipeng., Hong, Yuancheng. Determination of glucosinolates in 19 Chinese medicinal plants with spectrophotometry and high-pressure liquid chromatography . Natural product research, 2010, vol. 24, no. 13, p. 1195-1205. DOI
  2. Mehmood, Malik Hassan., Rehman, Abdul., Rehman, Najeeb-ur., Gilani, Anwarul-Hassan. Studies on Prokinetic, Laxative and Spasmodic Activities of Phyllanthus emblica in Experimental Animals . Phytotherapy research, 2013, vol. 27, no. 7, p. 1054-1060. DOI
  3. Patil, Smita G., Jadhav, Varsha M., Kadam, Vilasrao J. Method development and validation for simultaneous estimation of gallic acid and piperine in herbal extract and polyherbal formulation by HPTLC. World journal of pharmacy and pharmaceutical sciences, 2015, vol. 4, no. 1, p. 738-748.
  4. Avula, Bharathi., Wang, Yan-Hong., Wang, Mei., Shen, Yun-Heng., Khan, Ikhlas A. Simultaneous Determination and Characterization of Tannins and Triterpene Saponins from the Fruits of Various Species of Terminalia and Phyllantus emblica Using a UHPLC-UV-MS Method: Application to Triphala. PLANTA MEDICA, 2013, vol. 79, no. 2, p. 181-188. DOI
  5. Srivastava, Satendra K., Ranjan, Shri. Physiological studies on plant tannis. II. Variation of tannin compounds in the leaves and twigs of Emblica officinalis during fruiting season. Flora (jena), abteilung a: physiologie und biochemie, 1966, vol. 157, no. 3, p. 201-10.
  6. Yang, Baoru., Kortesniemi, Maaria., Liu, Pengzhan., Karonen, Maarit., Salminen, Juha-Pekka. Analysis of Hydrolyzable Tannins and Other Phenolic Compounds in Emblic Leafflower (Phyllanthus emblica L.) Fruits by High Performance Liquid Chromatography-Electrospray Ionization Mass Spectrometry . Journal of agricultural and food chemistry, 2012, vol. 60, no. 35, p. 8672-8683. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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