Botanical species · safety record
Phyllanthus emblica
The EFSA Compendium of Botanicals holds 18 constituent measurements and 2 adverse-effect records for Phyllanthus emblica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Phyllanthus emblica L.
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 726 licensed products naming Phyllanthus emblica as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Ellagitannins (hydrolysable tannins)4
- Beta-glucogallin2
- Gallic acid2
- Glucosinolates2
- Sinigrin2
- Alkaloids1
- Chebulagic acid1
- Corilagin1
- Coumarins1
- Piperine1
Plant parts
- Fruit unspecified12
- Seed4
- Leaves2
- Stem2
- stalk2
Preparations
- Solvent extraction20
Effect types
- Digestive2
Target tissues
- Digestive2
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Fruit unspecified | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Chebulagic acid | Fruit unspecified | Solvent extraction | — | — | Resolve DOI |
| Corilagin | Fruit unspecified | Solvent extraction | — | — | Resolve DOI |
| Coumarins | Fruit unspecified | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Ellagitannins (hydrolysable tannins) | Fruit unspecified | Solvent extraction | — | — | Resolve DOI |
| Ellagitannins (hydrolysable tannins) | Fruit unspecified | Solvent extraction | — | LC-MS | Resolve DOI |
| Gallic acid | Fruit unspecified | Solvent extraction | — | — | Resolve DOI |
| Glucosinolates | Seed | Solvent extraction | ≤ 56.598 Millimole/kilogram | HPLC-UV | Resolve DOI |
| Glucosinolates | Seed | Solvent extraction | ≥ 59.918 Millimole/kilogram | HPLC-UV | Resolve DOI |
| Saponins | Fruit unspecified | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Sinigrin | Seed | Solvent extraction | ≤ 35.927 Millimole/kilogram | HPLC-UV | Resolve DOI |
| Sinigrin | Seed | Solvent extraction | ≥ 36.147 Millimole/kilogram | HPLC-UV | Resolve DOI |
| Beta-glucogallin | Stem / stalk | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Beta-glucogallin | Leaves | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Ellagitannins (hydrolysable tannins) | Stem / stalk | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Ellagitannins (hydrolysable tannins) | Leaves | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Gallic acid | Fruit unspecified | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Piperine | Fruit unspecified | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Digestive | Digestive | Fruit unspecified | Solvent extraction | House mouse (as animal) | Acute toxicity | Resolve DOI |
| Digestive | Digestive | Fruit unspecified | Solvent extraction | House mouse (as animal) | Acute toxicity | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Hu, Ye., Liang, Hao., Yuan, Qipeng., Hong, Yuancheng. Determination of glucosinolates in 19 Chinese medicinal plants with spectrophotometry and high-pressure liquid chromatography . Natural product research, 2010, vol. 24, no. 13, p. 1195-1205. DOI
- Mehmood, Malik Hassan., Rehman, Abdul., Rehman, Najeeb-ur., Gilani, Anwarul-Hassan. Studies on Prokinetic, Laxative and Spasmodic Activities of Phyllanthus emblica in Experimental Animals . Phytotherapy research, 2013, vol. 27, no. 7, p. 1054-1060. DOI
- Patil, Smita G., Jadhav, Varsha M., Kadam, Vilasrao J. Method development and validation for simultaneous estimation of gallic acid and piperine in herbal extract and polyherbal formulation by HPTLC. World journal of pharmacy and pharmaceutical sciences, 2015, vol. 4, no. 1, p. 738-748.
- Avula, Bharathi., Wang, Yan-Hong., Wang, Mei., Shen, Yun-Heng., Khan, Ikhlas A. Simultaneous Determination and Characterization of Tannins and Triterpene Saponins from the Fruits of Various Species of Terminalia and Phyllantus emblica Using a UHPLC-UV-MS Method: Application to Triphala. PLANTA MEDICA, 2013, vol. 79, no. 2, p. 181-188. DOI
- Srivastava, Satendra K., Ranjan, Shri. Physiological studies on plant tannis. II. Variation of tannin compounds in the leaves and twigs of Emblica officinalis during fruiting season. Flora (jena), abteilung a: physiologie und biochemie, 1966, vol. 157, no. 3, p. 201-10.
- Yang, Baoru., Kortesniemi, Maaria., Liu, Pengzhan., Karonen, Maarit., Salminen, Juha-Pekka. Analysis of Hydrolyzable Tannins and Other Phenolic Compounds in Emblic Leafflower (Phyllanthus emblica L.) Fruits by High Performance Liquid Chromatography-Electrospray Ionization Mass Spectrometry . Journal of agricultural and food chemistry, 2012, vol. 60, no. 35, p. 8672-8683. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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