Botanical species · safety record

Phyllanthus niruri

The EFSA Compendium of Botanicals holds 14 constituent measurements for Phyllanthus niruri. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Phyllanthus niruri L.

14Constituent measurements
0Safety records
5Cited sources
101Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 101 licensed products naming Phyllanthus niruri as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry

Source material stated

  • Aerial parts
  • Fruit
  • Herb
  • Herb top
  • Herb top and root
  • Leaf
  • Leaf extract
  • Leaf/Leaves

What the records describe

Constituents measured

  • Alkaloids4
  • Saponins2
  • Tannins2
  • Anthraquinones1
  • Corilagin1
  • Coumarins1
  • Geraniin1
  • Lignans1
  • Naphthoquinones1

Plant parts

  • Aerial part of plants5
  • Unspecified5
  • Leaves2
  • Roots and other underground parts1
  • Stem1
  • stalk1

Preparations

  • Solvent extraction8

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsAerial part of plantsSolvent extractionPhytochemical screeningResolve DOI
CorilaginUnspecifiedUnspecifiedResolve DOI
CoumarinsLeavesUnspecifiedResolve DOI
GeraniinUnspecifiedUnspecifiedResolve DOI
LignansUnspecifiedUnspecifiedResolve DOI
SaponinsAerial part of plantsSolvent extractionPhytochemical screeningResolve DOI
SaponinsUnspecifiedUnspecifiedResolve DOI
TanninsUnspecifiedUnspecifiedResolve DOI
TanninsAerial part of plantsSolvent extractionPhytochemical screeningResolve DOI
AlkaloidsLeavesSolvent extraction0.627 Milligram/gramStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
AlkaloidsRoots and other underground partsSolvent extraction0.742 Milligram/gramStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
AlkaloidsStem / stalkSolvent extraction0.78 Milligram/gramStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
AnthraquinonesAerial part of plantsSolvent extractionPhytochemical screeningNo resolvable identifier
NaphthoquinonesAerial part of plantsSolvent extractionPhytochemical screeningNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. de Queiroz, Fernando Marlisson., de Oliveira Matias, Kayo Wanderson., Freire da Cunha, Mylena Mylana., Schwarz, Aline. Evaluation of (anti) genotoxic activities of Phyllanthus niruri L. in rat bone marrow using the micronucleus test. BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2013, vol. 49, no. 1, p. 135-148.
  2. Eze, C.O., Nworu, C.S., Esimone, C.O., Okore, V.C. Immunomodulatory activities of methanol extract of the whole aerial part of Phyllantus niruri L. Journal of Pharmacognosy and Phytotherapy, 2014, vol. 6, no. 4, p. 41-46. DOI
  3. Chauhan, Preeta., Kumar, Padma. Influence of alkylating agent (EMS) on production of alkaloid contents in Phyllanthus niruri. International journal of plant sciences (muzaffarnagar, india), 2007, p. 219-220.
  4. Bagalkotkar, G., Sagineedu, S. R., Saad, M. S., Stanslas, J. Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review . Journal of pharmacy and pharmacology, 2006, vol. 58, no. 12, p. 1559-1570. DOI
  5. Nascimenlo, J.E., Melo, A.F.M., Lima E Silva, T.C., Veras Filho, J., Santos, E.M., Albuquerque, U.P., Amorim, E.L.C. Phytochemical screening and toxicological bioassay with brine shrimp larvae (Artemia salina Leachj of three medicinal species of the genus Phyllanthus (Phyllanthaceae) Estudo Fitoqu�mico e bioensaio toxicol�gico frentea larvasde Artemia salina Leach.detres esp�cies medicinais do genero Phyllanthus (Phyllanthaceae) . Revista de ciencias farmaceuticas basica e aplicada, 2008, vol. 29, no. 2, p. 143-148.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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