Botanical species · safety record
Phyllanthus niruri
The EFSA Compendium of Botanicals holds 14 constituent measurements for Phyllanthus niruri. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Phyllanthus niruri L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 101 licensed products naming Phyllanthus niruri as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Alkaloids4
- Saponins2
- Tannins2
- Anthraquinones1
- Corilagin1
- Coumarins1
- Geraniin1
- Lignans1
- Naphthoquinones1
Plant parts
- Aerial part of plants5
- Unspecified5
- Leaves2
- Roots and other underground parts1
- Stem1
- stalk1
Preparations
- Solvent extraction8
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Aerial part of plants | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Corilagin | Unspecified | — | — | Unspecified | Resolve DOI |
| Coumarins | Leaves | — | — | Unspecified | Resolve DOI |
| Geraniin | Unspecified | — | — | Unspecified | Resolve DOI |
| Lignans | Unspecified | — | — | Unspecified | Resolve DOI |
| Saponins | Aerial part of plants | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Saponins | Unspecified | — | — | Unspecified | Resolve DOI |
| Tannins | Unspecified | — | — | Unspecified | Resolve DOI |
| Tannins | Aerial part of plants | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Alkaloids | Leaves | Solvent extraction | 0.627 Milligram/gram | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Alkaloids | Roots and other underground parts | Solvent extraction | 0.742 Milligram/gram | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Alkaloids | Stem / stalk | Solvent extraction | 0.78 Milligram/gram | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Anthraquinones | Aerial part of plants | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
| Naphthoquinones | Aerial part of plants | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- de Queiroz, Fernando Marlisson., de Oliveira Matias, Kayo Wanderson., Freire da Cunha, Mylena Mylana., Schwarz, Aline. Evaluation of (anti) genotoxic activities of Phyllanthus niruri L. in rat bone marrow using the micronucleus test. BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2013, vol. 49, no. 1, p. 135-148.
- Eze, C.O., Nworu, C.S., Esimone, C.O., Okore, V.C. Immunomodulatory activities of methanol extract of the whole aerial part of Phyllantus niruri L. Journal of Pharmacognosy and Phytotherapy, 2014, vol. 6, no. 4, p. 41-46. DOI
- Chauhan, Preeta., Kumar, Padma. Influence of alkylating agent (EMS) on production of alkaloid contents in Phyllanthus niruri. International journal of plant sciences (muzaffarnagar, india), 2007, p. 219-220.
- Bagalkotkar, G., Sagineedu, S. R., Saad, M. S., Stanslas, J. Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review . Journal of pharmacy and pharmacology, 2006, vol. 58, no. 12, p. 1559-1570. DOI
- Nascimenlo, J.E., Melo, A.F.M., Lima E Silva, T.C., Veras Filho, J., Santos, E.M., Albuquerque, U.P., Amorim, E.L.C. Phytochemical screening and toxicological bioassay with brine shrimp larvae (Artemia salina Leachj of three medicinal species of the genus Phyllanthus (Phyllanthaceae) Estudo Fitoqu�mico e bioensaio toxicol�gico frentea larvasde Artemia salina Leach.detres esp�cies medicinais do genero Phyllanthus (Phyllanthaceae) . Revista de ciencias farmaceuticas basica e aplicada, 2008, vol. 29, no. 2, p. 143-148.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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