Botanical species · safety record

Physalis alkekengi

The EFSA Compendium of Botanicals holds 7 constituent measurements and 2 adverse-effect records for Physalis alkekengi. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Physalis alkekengi L.

7Constituent measurements

2Safety records

6Cited sources

10Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 10 licensed products naming Physalis alkekengi as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Berries
Berry/Berries

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Coumarins	Unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
P-coumaric acid	Unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Phygrine	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Steroid derivatives	Unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
3alpha-tigloyloxytropane	Fruit unspecified	—	—	Unspecified	No resolvable identifier
Alpha-solanine	Stem / stalk	Solvent extraction	0.2818 Microgram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Scopoletin	Leaves	Solvent extraction	≤ 267.9 Milligram/100 gram	UHPLC-MS-MS	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Endocrine	Testes	Aerial part of plants	Solvent extraction	Rat (as animal)	Subchronic	No resolvable identifier
Reproductive	Testes	Aerial part of plants	Solvent extraction	Rat (as animal)	Subchronic	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Javdan, N., Estakhr, J. Physalis alkekengi reduces spermatogenesis and cAMP-responsive element modulator gene expression in rat. Pharmacologyonline, 2011, vol. 2, p. 866-873.
Butnaru, Claudia., Vlase, Laurian., Lazar, Doina., Agoroaei, Luminita., Lazar, Mihai Ioan. HPLC/MS ANALYSIS OF SOLANINE IN PHYSALIS ALKEKENGI AND SOLANUM DULCAMARA. Farmacia, 2011, vol. 59, no. 2, p. 172-178.
Zhang, N., Chu, X.-Q., Jiang, J.-Q. Chemical constituents in ethyl acetate extract from Physalis alkekengi var. franchetii. Chinese traditional and herbal drugs, 2015, vol. 46, no. 8, p. 1120-1124. DOI
Butnaru, Claudia., Butnaru, Elena., Vlase, Laurian., Lazar, Mihai Ioan. DETERMINATION OF SCOPOLETIN IN PHYSALIS ALKEKENGY AND SOLANUM DULCAMARA BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY . Farmacia, 2010, vol. 58, no. 6, p. 711-718.
BASEY, K., MCGAW, BA., WOOLLEY, JG. PHYGRINE, AN ALKALOID FROM PHYSALIS SPECIES. Phytochemistry, 1992, vol. 31, no. 12, p. 4173-4176. DOI
Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. 3alpha-Tigloyloxytropane N-oxide (HMDB33454). Human metabolome database, 2012.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue

Independent literature