Botanical species · safety record
Pieris formosa
The EFSA Compendium of Botanicals holds 15 constituent measurements and 1 adverse-effect record for Pieris formosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Pieris formosa (Wall.) D.Don.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Diterpene alkaloids5
- Diterpenes2
- Grayanotoxins2
- Pierisformotoxin d2
- Grayanotoxin ii1
- Pierisformotoxin a1
- Pierisformotoxin b1
- Pierisformotoxin c1
Plant parts
- Aerial part of plants6
- Flower6
- Fruit unspecified2
- Leaves1
Preparations
- Solvent extraction15
Effect types
- Neurotoxicity1
Target tissues
- Neurologic: central nervous system1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Diterpene alkaloids | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Diterpene alkaloids | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Diterpene alkaloids | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Diterpene alkaloids | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Diterpene alkaloids | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Diterpenes | Fruit unspecified | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Diterpenes | Flower | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Grayanotoxin ii | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Grayanotoxins | Flower | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Pierisformotoxin a | Flower | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Pierisformotoxin b | Flower | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Pierisformotoxin c | Flower | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Pierisformotoxin d | Flower | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Grayanotoxins | Leaves | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Pierisformotoxin d | Fruit unspecified | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Neurotoxicity | Neurologic: central nervous system | — | — | — | Not reported | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Wang, Wei-Guang., Wu, Zhao-Yuan., Chen, Rui., Li, Hai-Zhou., Li, Hong-Mei., Li, Yuan-Dan., Li, Rong-Tao., Luo, Huai-Rong. Pierisformotoxins A-D, Polyesterified Grayanane Diterpenoids from Pieris formosa and Their cAMP-Decreasing Activities . Chemistry & biodiversity, 2013, vol. 10, no. 6, p. 1061-1071. DOI
- Zhang, Eer-Iiang., Guan, Mi-jia., Yan, Ping., Dong, Liang. Study on the mechanism of action of Pieris formosa. Indian veterinary journal, 2001, vol. 78, no. 12, p. 1098-1101.
- Niu, Chang-Shan., Li, Yong., Liu, Yun-Bao., Ma, Shuang-Gang., Li, Li., Qu, Jing., Yu, Shi-Shan. Analgesic diterpenoids from the twigs of Pieris formosa. Tetrahedron, 2016, vol. 72, no. 1, p. 44-49. DOI
- Wu, Zhao-Yuan., Li, Hai-Zhou., Wang, Wei-Guang., Li, Xiao-Lei., Li, Rong-Tao. Secopieristoxins A and B, two unusual diterpenoids with a new 9,10-secograyanane skeleton from the fruits of Pieris formosa . Phytochemistry letters, 2012, vol. 5, no. 1, p. 87-90. DOI
- Li, Chun-Huan., Niu, Xue-Mei., Luo, Qian., Xie, Ming-Jin., Luo, Shi-Hong., Zhou, Yan-Ying., Li, Sheng-Hong. Novel Polyesterified 334-seco-Grayanane Diterpenoids as Antifeedants from Pieris formosa . Organic letters, 2010, vol. 12, no. 10, p. 2426-2429. DOI
- Wang, L.-Q., Ding, B.-Y., Wang, P., Zhao, W.-M., Qin, G.-W. Grayanane diterpenoids from Pieris formosa. Natural product sciences, 1998, vol. 4, no. 2, p. 68-71.
- Wang, Wei-Guang., Li, Hong-Mei., Li, Hai-Zhou., Wu, Zhao-Yuan., Li, Rong-Tao. New grayanol diterpenoid and new phenolic glucoside from the flowers of Pieris formosa . Journal of asian natural products research, 2010, vol. 12, no. 1, p. 70-75. DOI
- Wu, Zhao-Yuan., Li, Yuan-Dan., Wu, Gui-Sheng., Luo, Huai-Rong., Li, Hong-Mei., Li, Rong-Tao. Three New Highly Acylated 3,4-seco-Grayanane Diterpenoids from the Fruits of Pieris formosa . Chemical & pharmaceutical bulletin, 2011, vol. 59, no. 4, p. 492-495.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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