Botanical species · safety record

Pimpinella anisum

The EFSA Compendium of Botanicals holds 18 constituent measurements for Pimpinella anisum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Pimpinella anisum L.

18Constituent measurements
0Safety records
6Cited sources
167Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 167 licensed products naming Pimpinella anisum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Extract Type TBA
  • Fresh

Source material stated

  • Fruit
  • Fruit(s)
  • Grain(s)
  • Graine
  • New material
  • Pimpinella anisum - Fruit
  • Pimpinella anisum - Seed
  • Root

What the records describe

Constituents measured

  • Auraptene2
  • Coumarin2
  • Estragole2
  • Umbelliferone2
  • Umbelliprenin2
  • Cis-isoeugenol1
  • Daidzin1
  • Formononetin1
  • Glycitein1
  • Glycitin1

Plant parts

  • Seed13
  • Aerial part of plants3
  • Fruit unspecified1
  • Unspecified1

Preparations

  • Solvent extraction15
  • Essential oil3

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AurapteneSeedSolvent extraction≤ 2.03 Milligram/gramHPLC-UVResolve DOI
AurapteneSeedSolvent extraction≥ 0.95 Milligram/gramHPLC-UVResolve DOI
Cis-isoeugenolFruit unspecifiedEssential oil1.99 PercentGC-MSResolve DOI
CoumarinSeedSolvent extraction≤ 3.34 Milligram/gramHPLC-UVResolve DOI
CoumarinSeedSolvent extraction≥ 1.08 Milligram/gramHPLC-UVResolve DOI
EstragoleUnspecifiedEssential oil1 PercentUnspecifiedResolve DOI
EstragoleSeedEssential oil2.2 PercentGC-MS (Q)Resolve DOI
UmbelliferoneSeedSolvent extraction≥ 0.63 Milligram/gramHPLC-UVResolve DOI
UmbelliferoneSeedSolvent extraction≤ 0.76 Milligram/gramHPLC-UVResolve DOI
UmbellipreninSeedSolvent extraction≤ 10.22 Milligram/gramHPLC-UVResolve DOI
UmbellipreninSeedSolvent extraction≥ 0.7 Milligram/gramHPLC-UVResolve DOI
DaidzinSeedSolvent extraction0.3 Milligram/kilogramHPLC-MS/MSNo resolvable identifier
FormononetinSeedSolvent extraction0.3 Milligram/kilogramHPLC-MS/MSNo resolvable identifier
GlyciteinSeedSolvent extraction1 Milligram/kilogramHPLC-MS/MSNo resolvable identifier
GlycitinSeedSolvent extraction1 Milligram/kilogramHPLC-MS/MSNo resolvable identifier
HeliotrineAerial part of plantsSolvent extraction5.4 Microgram/100 gramHPLC-MS/MSNo resolvable identifier
SolamargineAerial part of plantsSolvent extraction2.5 Microgram/100 gramHPLC-MS/MSNo resolvable identifier
SolasonineAerial part of plantsSolvent extraction11.8 Microgram/100 gramHPLC-MS/MSNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family.. Biochemical systematics and ecology, 2012, vol. 45, p. 237-243.
  2. Taddeo, Vito Alessandro., Genovese, Salvatore., de Medina, Philippe., Palmisano, Roberta., Epifano, Francesco., Fiorito, Serena. Quantification of biologically active O-prenylated and unprenylated phenylpropanoids in dill (Anethum graveolens), anise (Pimpinella anisum), and wild celery (Angelica archangelica) . Journal of pharmaceutical and biomedical analysis, 2017, vol. 134, p. 319-324. DOI
  3. Samojlik, Isidora., Mijatovic, Vesna., Petkovic, Stojan., Skrbic, Biljana., Bozin, Biljana. The influence of essential oil of aniseed (Pimpinella anisum, L.) on drug effects on the central nervous system . Fitoterapia, 2012, vol. 83, no. 8, p. 1466-1473. DOI
  4. Nardin, Tiziana., Piasentier, Edi., Barnaba, Chiara., Larcher, Roberto. Alkaloid profiling of herbal drugs using high resolution mass spectrometry. Drug testing and analysis, 2017, p. Ahead of Print.
  5. De Vincenzi, M., Silano, M., Maialetti, F., Scazzocchio, B. Constituents of aromatic plants: II. Estragole. FITOTERAPIA, 2000, vol. 71, no. 6, p. 725-729. DOI
  6. Dhima, Kico., Vasilakoglou, Ioannis., Garane, Vassiliki., Ritzoulis, Christos., Lianopoulou, Vaia., Panou-Philotheou, Eleni. Competitiveness and Essential Oil Phytotoxicity of Seven Annual Aromatic Plants . Weed science, 2010, vol. 58, no. 4, p. 457-465. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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