Botanical species · safety record
Pimpinella anisum
The EFSA Compendium of Botanicals holds 18 constituent measurements for Pimpinella anisum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Pimpinella anisum L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 167 licensed products naming Pimpinella anisum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Auraptene2
- Coumarin2
- Estragole2
- Umbelliferone2
- Umbelliprenin2
- Cis-isoeugenol1
- Daidzin1
- Formononetin1
- Glycitein1
- Glycitin1
Plant parts
- Seed13
- Aerial part of plants3
- Fruit unspecified1
- Unspecified1
Preparations
- Solvent extraction15
- Essential oil3
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Auraptene | Seed | Solvent extraction | ≤ 2.03 Milligram/gram | HPLC-UV | Resolve DOI |
| Auraptene | Seed | Solvent extraction | ≥ 0.95 Milligram/gram | HPLC-UV | Resolve DOI |
| Cis-isoeugenol | Fruit unspecified | Essential oil | 1.99 Percent | GC-MS | Resolve DOI |
| Coumarin | Seed | Solvent extraction | ≤ 3.34 Milligram/gram | HPLC-UV | Resolve DOI |
| Coumarin | Seed | Solvent extraction | ≥ 1.08 Milligram/gram | HPLC-UV | Resolve DOI |
| Estragole | Unspecified | Essential oil | 1 Percent | Unspecified | Resolve DOI |
| Estragole | Seed | Essential oil | 2.2 Percent | GC-MS (Q) | Resolve DOI |
| Umbelliferone | Seed | Solvent extraction | ≥ 0.63 Milligram/gram | HPLC-UV | Resolve DOI |
| Umbelliferone | Seed | Solvent extraction | ≤ 0.76 Milligram/gram | HPLC-UV | Resolve DOI |
| Umbelliprenin | Seed | Solvent extraction | ≤ 10.22 Milligram/gram | HPLC-UV | Resolve DOI |
| Umbelliprenin | Seed | Solvent extraction | ≥ 0.7 Milligram/gram | HPLC-UV | Resolve DOI |
| Daidzin | Seed | Solvent extraction | 0.3 Milligram/kilogram | HPLC-MS/MS | No resolvable identifier |
| Formononetin | Seed | Solvent extraction | 0.3 Milligram/kilogram | HPLC-MS/MS | No resolvable identifier |
| Glycitein | Seed | Solvent extraction | 1 Milligram/kilogram | HPLC-MS/MS | No resolvable identifier |
| Glycitin | Seed | Solvent extraction | 1 Milligram/kilogram | HPLC-MS/MS | No resolvable identifier |
| Heliotrine | Aerial part of plants | Solvent extraction | 5.4 Microgram/100 gram | HPLC-MS/MS | No resolvable identifier |
| Solamargine | Aerial part of plants | Solvent extraction | 2.5 Microgram/100 gram | HPLC-MS/MS | No resolvable identifier |
| Solasonine | Aerial part of plants | Solvent extraction | 11.8 Microgram/100 gram | HPLC-MS/MS | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family.. Biochemical systematics and ecology, 2012, vol. 45, p. 237-243.
- Taddeo, Vito Alessandro., Genovese, Salvatore., de Medina, Philippe., Palmisano, Roberta., Epifano, Francesco., Fiorito, Serena. Quantification of biologically active O-prenylated and unprenylated phenylpropanoids in dill (Anethum graveolens), anise (Pimpinella anisum), and wild celery (Angelica archangelica) . Journal of pharmaceutical and biomedical analysis, 2017, vol. 134, p. 319-324. DOI
- Samojlik, Isidora., Mijatovic, Vesna., Petkovic, Stojan., Skrbic, Biljana., Bozin, Biljana. The influence of essential oil of aniseed (Pimpinella anisum, L.) on drug effects on the central nervous system . Fitoterapia, 2012, vol. 83, no. 8, p. 1466-1473. DOI
- Nardin, Tiziana., Piasentier, Edi., Barnaba, Chiara., Larcher, Roberto. Alkaloid profiling of herbal drugs using high resolution mass spectrometry. Drug testing and analysis, 2017, p. Ahead of Print.
- De Vincenzi, M., Silano, M., Maialetti, F., Scazzocchio, B. Constituents of aromatic plants: II. Estragole. FITOTERAPIA, 2000, vol. 71, no. 6, p. 725-729. DOI
- Dhima, Kico., Vasilakoglou, Ioannis., Garane, Vassiliki., Ritzoulis, Christos., Lianopoulou, Vaia., Panou-Philotheou, Eleni. Competitiveness and Essential Oil Phytotoxicity of Seven Annual Aromatic Plants . Weed science, 2010, vol. 58, no. 4, p. 457-465. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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