Botanical species · safety record

Pinellia ternata

The EFSA Compendium of Botanicals holds 13 constituent measurements, 1 adverse-effect record and 1 genotoxicity assay for Pinellia ternata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Pinellia ternata (Thunb.) Makino

13Constituent measurements

2Safety records

7Cited sources

1,152Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1,152 licensed products naming Pinellia ternata as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
solid

Source material stated

Artemisia annua, whole plant
Dried tuber
Dried tuber (processed)
Fermented Rhizome
Fruit
Ginger processed rhizome
Leaf
Pinella ternate, tuber

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Lectins	Roots and other underground parts used as staple food	Solvent extraction	35.5 Milligram/gram	Unspecified	Resolve DOI
Methyleugenol	Roots and other underground parts used as staple food	Essential oil	6.2 Percent	GC-MS	Resolve DOI
Myristicin	Roots and other underground parts used as staple food	Essential oil	1.5 Percent	GC-MS	Resolve DOI
Safrole	Roots and other underground parts used as staple food	Essential oil	1.7 Percent	GC-MS	Resolve DOI
Calcium oxalate	Roots and other underground parts used as staple food	—	86.73 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Coniferin	Roots and other underground parts	Solvent extraction	—	Unspecified	No resolvable identifier
Harmane alkaloids	Unspecified	Solvent extraction	≥ 26.7 Nanogram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Harmane alkaloids	Unspecified	Solvent extraction	≤ 123 Nanogram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Harmine	Unspecified	Solvent extraction	< 16.6 Nanogram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Lignans	Roots and other underground parts	Solvent extraction	—	Unspecified	No resolvable identifier
Norharmane	Unspecified	Solvent extraction	≤ 96.2 Nanogram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Norharmane	Unspecified	Solvent extraction	≥ 17.6 Nanogram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Phenylpropanoids	Roots and other underground parts	Solvent extraction	—	Unspecified	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Roots and other underground parts used as staple food	Solvent extraction	House mouse (as animal)	Short-term toxicity	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	—	Mammalian erythrocyte micronucleus test	House mouse (as animal)	—	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Tsuchiya, Hironori., Hayashi, Hideaki., Sato, Masaru., Shimizu, Hiroshi., Iinuma, Munekazu. Quantitative analysis of all types of beta-carboline alkaloids in medicinal plants and dried edible plants by high performance liquid chromatography with selective fluorometric detection. Phytochemical analysis, 1999, vol. 10, no. 5, p. 247-253.
Han, Mei-hua., Yang, Xiu-wei., Zhong, Guo-yue., Zhang, Ming. Bioactive constituents inhibiting TNF-alpha production in fresh rhizome of Pinellia ternata . . Zhongguo zhong yao za zhi = zhongguo zhongyao zazhi = china journal of chinese materia medica, 2007, vol. 32, no. 17, p. 1755-9.
Iwasa, Megumi., Iwasaki, Toshiki., Ono, Toshirou., Miyazawa, Mitsuo. Chemical Composition and Major Odor-Active Compounds of Essential Oil from PINELLIA TUBER (Dried Rhizome of Pinellia ternata) as Crude Drug . Journal of oleo science, 2014, vol. 63, no. 2, p. 127-135. DOI
bagjiha. Micronucleus Test of Pinella Rhizoma Aqueous Extracts in Bone Marrow Cells of Male ICR Mice - In Vivo Genotoxicity . Korea journal of oriental medicine, 2009, vol. 15, no. 3, p. 99-105.
Lim, Young-Kwon., Park, Ji-Ha., Seo, Bu-Il., Roh, Seong-Soo., Ku, Sae-Kwang. Single Oral Dose Toxicity Study of Pinelliae Rhizoma Aqueous Extract in ICR Mice . Toxicological research, 2009, vol. 25, no. 3, p. 147-157.
Zhou, Wei., Gao, Yong., Xu, Shaowei., Yang, Zhili., Xu, Tao. Purification of a mannose-binding lectin Pinellia ternata agglutinin and its induction of apoptosis in Bel-7404 cells . Protein expression and purification, 2014, vol. 93, p. 11-17. DOI
Ge, Xiuyun., Wu, Hao. Analysis of composition of poisonous raphides in Araceae plant. Yaowu fenxi zazhi, 2010, vol. 30, no. 2, p. 190-193.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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