Botanical species · safety record

Plantago major

The EFSA Compendium of Botanicals holds 2 constituent measurements, 1 adverse-effect record and 1 genotoxicity assay for Plantago major. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Plantago major L.

2Constituent measurements

2Safety records

3Cited sources

161Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 161 licensed products naming Plantago major as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Fresh

Source material stated

Aerial parts
Fresh aerial part
Fresh aerial parts
Fresh whole flowering plant
Fruit
Grass(es)
Herb
Leaf

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Erucic acid	Leaves	Solvent extraction	3.45 Percent	Gaschromatography (GC)	Resolve DOI
Oxalates	Leaves	Solvent extraction	0.67 Milligram/100 gram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Other toxicities	Neurologic: central nervous system	Leaves	Solvent extraction	Rat (as animal)	Subchronic	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	genome mutation	somatic mutation assay in Drosophila	Drosophila melanogaster (as animal)	—	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Guil, JL., Rodriguez-Garcia, I., Torija, E. Nutritional and toxic factors in selected wild edible plants. PLANT FOODS FOR HUMAN NUTRITION, 1997, vol. 51, no. 2, p. 99-107. DOI
Pimenta, VMSD., Nepomuceno, JC. Genotoxicity testing of Plantago major extracts in somatic cells of Drosophila melanogaster . Environmental and molecular mutagenesis, 2005, vol. 45, no. 1, p. 56-61. DOI
Gonzalez, MG., Coto-Morales, T., Rodriguez, GAS., Pazos, L. Sub-chronic toxicity and test of eye irritability of leaf aqueous extract from Plantago major (Plantaginaceae) . Revista de biologia tropical, 2003, vol. 51, no. 3-4, p. 635-638.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue

Independent literature