Botanical species · safety record

Plectranthus barbatus

The EFSA Compendium of Botanicals holds 6 constituent measurements and 1 adverse-effect record for Plectranthus barbatus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Plectranthus barbatus Andrews

6Constituent measurements

1Safety records

6Cited sources

197Licensed products (Canada)

Also recorded as

Coleus barbatus (Andrews) Benth ex. G.Don

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 197 licensed products naming Plectranthus barbatus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA

Source material stated

Bark
Herb top and root
New material
Plante entière
Rhizome and root(s)
Root
Root extract
Whole plant

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Diterpenes	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Forskolin	Roots and other underground parts	Solvent extraction	—	Unspecified	Resolve DOI
Labdane diterpenes	Unspecified	Solvent extraction	—	Unspecified	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≤ 1.6 Percent	GC-MS	No resolvable identifier
Alpha-thujone	Aerial part of plants	Essential oil	≥ 0.4 Percent	GC-MS	No resolvable identifier
Diterpenes	Leaves	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Reproductive	Bone (deprecated)	Leaves	Solvent extraction	Rat (as animal)	Not reported	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Verissimo, Luiz Fernando., Bacchi, Andre D., Zaminelli, Tiago., de Paula, Gustavo Henrique O., Moreira, Estefania G. Herbs of interest to the Brazilian Federal Government: female reproductive and developmental toxicity studies . Revista brasileira de farmacognosia-brazilian journal of pharmacognosy, 2011, vol. 21, no. 6, p. 1163-1171.
Alasbahi, R. H., Melzig, M. F. Forskolin and derivatives as tools for studying the role of cAMP. Pharmazie, 2012, vol. 67, no. 1, p. 5-13. DOI
Alasbahi, Rawiya H., Melzig, Matthias F. Plectranthus barbatus: A Review of Phytochemistry, Ethnobotanical Uses and Pharmacology - Part 1 . Planta medica, 2010, vol. 76, no. 7, p. 653-661. DOI
Mothana, Ramzi A., Al-Said, Mansour S., Al-Musayeib, Nawal M., El Gamal, Ali A., Al-Massarani, Shaza M., Al-Rehaily, Adnan J., Abdulkader, Majed., Maes, Louis. In Vitro Antiprotozoal Activity of Abietane Diterpenoids Isolated from Plectranthus barbatus Andr. . International journal of molecular sciences, 2014, vol. 15, no. 5, p. 8360-8371. DOI
Muhayimana, Ancilla., Chalchat, Jean-Claude., Garry, Raymond-Philippe. Chemical composition of essential oils of some medicinal plants from Rwanda. Journal of essential oil research, 1998, vol. 10, no. 3, p. 251-259.
de Albuquerque, Roberto L., Kentopff, Marta R., Machado, Maria Iracema L., Silva, Maria Goretti V., Matos, Francisco Jose de A., Morais, Selene M., Braz Filho, Raimundo. Abietane diterpenoids isolation from Plectranthus barbatus. Quimica nova, 2007, vol. 30, no. 8, p. 1882-1886.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature