Botanical species · safety record

Plumeria rubra

The EFSA Compendium of Botanicals holds 10 constituent measurements and 5 adverse-effect records for Plumeria rubra. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Plumeria rubra L.

10Constituent measurements

5Safety records

8Cited sources

1Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Plumeria rubra as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Flower

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Liriodendrin	Bark	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Alkaloids	Bark	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Alkaloids	Fruit unspecified	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Benzyl salicylate	Flower	Essential oil	1.37 Percent	GC-MS	No resolvable identifier
Calcium oxalate	Bark	—	—	Microscopical and histometrical tests	No resolvable identifier
Phenethyl salicylate	Flower	Essential oil	14.38 Percent	GC-MS	No resolvable identifier
Quinolizidine alkaloids	Stem / stalk	—	—	Unspecified	No resolvable identifier
Saponins	Fruit unspecified	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Fruit unspecified	Solvent extraction	—	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Endocrine	Urogenital: ovaries	Fruit unspecified	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier
Endocrine	Urogenital: ovaries	Fruit unspecified	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier
Reproductive	Uterus	Fruit unspecified	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier
Reproductive	Uterus	Fruit unspecified	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier
Reproductive	Testes	Leaves	Fresh	Rat (as animal)	Reproduction toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Jacob, Dennis., Yadava, Lajwanti., Vyas, D. K. Alterations in the phosphatase content of the genital organs of the male rat after administration of antifertility doses of Plumeria leaf, Daucus seed and stilbestrol. Journal of advanced zoology, 1988, p. 6-10.
Dabhadkar, Dinesh., Zade, Varsha. Abortifacient activity of Plumeria rubra (Linn) pod extract in female albino rats . Indian journal of experimental biology, 2012, vol. 50, no. 10, p. 702-707.
Dabhadkar, D., Zade, V., Dawada, S., Dhore, M., Kodape, M. Effect of alcoholic pod extract of Plumeria rubra on biochemical and haematologicalparameters of female albino rats. International journal of pharmaceutical sciences review and research, 2013, vol. 19, no. 1, p. 69-74.
Sharma, S.K.R., Kumar, N. Pharmacognostical standardisation of Plumeria acutifolia (Poir) bark. International journal of pharmacy and pharmaceutical sciences, 2012, vol. 4, no. SUPPL. 5, p. 54-57.
Hassan, E.M., Shahat, A.A., Ibrahim, N.A., Vlietinck, A.J., Apers, S., Pieters, L. A new monoterpene alkaloid and other constituents of Plumeria acutifolia. Planta medica, 2008, vol. 74, no. 14, p. 1749-1750. DOI
Omata, Akihiki., Yomogida, Katsuyuki., Nakamura, Shoji., Hashimoto, Seiji., Arai, Toshiyuki., Furukawa, Kiyoshi. Volatile components of Plumeria flowers. Part 1. Plumeria rubra forma acutifolia (Poir.) Woodson cv. 'Common Yellow'. Flavour and Fragrance Journal, 1991, p. 277-279.
KARDONO, LBS., TSAURI, S., PADMAWINATA, K., PEZZUTO, JM., KINGHORN, AD. STUDIES ON INDONESIAN MEDICINAL-PLANTS .2. CYTOTOXIC CONSTITUENTS OF THE BARK OF PLUMERIA-RUBRA COLLECTED IN INDONESIA . Journal of natural products, 1990, vol. 53, no. 6, p. 1447-1455. DOI
Kazmi, Syed Najam-ul-Hussain., Ahmed, Zaheer., Ahmed, Waseem., Malik, Abdul. Plumerinine - a novel lupine alkaloid from Plumeria rubra. Heterocycles, 1989, p. 1901-1906.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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