Botanical species · safety record

Podophyllum hexandrum

The EFSA Compendium of Botanicals holds 10 constituent measurements for Podophyllum hexandrum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Podophyllum hexandrum Royle

10Constituent measurements

0Safety records

2Cited sources

1Licensed products (Canada)

Also recorded as

Sinopodophyllum hexandrum (Royle) T.S.Ying
Podophyllum emodi Wall. ex Hook.f. & Thomson

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Podophyllum hexandrum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Deoxypodophyllotoxin	Roots and other underground parts	Solvent extraction	≤ 24.22 Percent	GC-MS	Resolve DOI
Deoxypodophyllotoxin	Roots and other underground parts	Solvent extraction	≥ 2.83 Percent	GC-MS	Resolve DOI
Hydroxymethylfurfural	Roots and other underground parts	Solvent extraction	28.65 Percent	GC-MS	Resolve DOI
Lignans	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Podophyllotoxin	Roots and other underground parts	Solvent extraction	≤ 18.91 Percent	GC-MS	Resolve DOI
Podophyllotoxin	Roots and other underground parts	Solvent extraction	≥ 0.47 Percent	GC-MS	Resolve DOI
Podophyllotoxin	Roots and other underground parts	Solvent extraction	≥ 2.92 Percent	GC-MS	Resolve DOI
Podophyllotoxin	Roots and other underground parts	Solvent extraction	≤ 21.13 Percent	GC-MS	Resolve DOI
Podophyllotoxin acetate	Roots and other underground parts	Solvent extraction	21.13 Percent	GC-MS	Resolve DOI
Solasodine	Roots and other underground parts	Solvent extraction	1.1 Percent	GC-MS	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Dar, Sabzar Ahmad., Yousuf, Abdul Rehman., Balkhi, Masood-ul-Hassan., Ganai, Bashir Ahmad., Tantry, Mudasir., Bhat, Farooz Ahmad. Podophyllum hexandrum ameliorates endosulfan-induced genotoxicity and mutagenicity in freshwater cyprinid fish crucian carp . Pharmaceutical biology, 2017, vol. 55, no. 1, p. 173-183. DOI
Sun, Yan-Jun., Li, Zhan-Lin., Chen, Hong., Liu, Xiao-Qiu., Zhou, Wei., Hua, Hui-Ming. Three new cytotoxic aryltetralin lignans from Sinopodophyllum emodi. Bioorganic & medicinal chemistry letters, 2011, vol. 21, no. 12, p. 3794-3797. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature