Botanical species · safety record
Polygala senega
The EFSA Compendium of Botanicals holds 12 constituent measurements for Polygala senega. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Polygala senega L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 18 licensed products naming Polygala senega as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Pentacyclic triterpene saponins8
- Saponins3
- Prosapogenin a1
Plant parts
- Roots and other underground parts11
- Unspecified1
Preparations
- Solvent extraction11
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Pentacyclic triterpene saponins | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Pentacyclic triterpene saponins | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Pentacyclic triterpene saponins | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Pentacyclic triterpene saponins | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Pentacyclic triterpene saponins | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Saponins | Roots and other underground parts | Solvent extraction | — | Unspecified | Resolve DOI |
| Saponins | Roots and other underground parts | Solvent extraction | 4.5 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Saponins | Roots and other underground parts | Solvent extraction | — | Unspecified | Resolve DOI |
| Pentacyclic triterpene saponins | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Pentacyclic triterpene saponins | Roots and other underground parts | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| Pentacyclic triterpene saponins | Roots and other underground parts | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| Prosapogenin a | Unspecified | — | — | Unspecified | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Arai, Masayoshi., Hayashi, Asami., Sobou, Mari., Ishida, Shunsuke., Kawachi, Takashi., Kotoku, Naoyuki., Kobayashi, Motomasa. Anti-angiogenic effect of triterpenoidal saponins from Polygala senega. Journal of natural medicines, 2011, vol. 65, no. 1, p. 149-156. DOI
- Ishida, H., Inaoka, Y., Okada, M., Fukushima, M., Fukazawa, H., Tsuji, K. Studies of the active substances in herbs used for hair treatment. III. Isolation of hair-regrowth substances from Polygara senega var. latifolia TORR-et GRAY . Biological & pharmaceutical bulletin, 1999, vol. 22, no. 11, p. 1249-1250.
- Sun, Hong-Xiang., Xie, Yong., Ye, Yi-Ping. Advances in saponin-based adjuvants. Vaccine, 2009, vol. 27, no. 12, p. 1787-1796. DOI
- Estrada, A., Katselis, GS., Laarveld, B., Barl, B. Isolation and evaluation of immunological adjuvant activities of saponins from Polygala senega L. . Comparative immunology microbiology and infectious diseases, 2000, vol. 23, no. 1, p. 27-43. DOI
- TSUKITANI, Y., KAWANISHI, S., SHOJI, J. STUDIES ON CONSTITUENTS OF SENEGAE RADIX .2. STRUCTURE OF SENEGIN-II, A SAPONIN FROM POLYGALA-SENEGA LINNE VAR LATIFOLIA TORRY AND GRAY . Chemical & pharmaceutical bulletin, 1973, vol. 21, no. 4, p. 791-799.
- Pelletier, S. William., Nakamura, Shoshiro. Prosapogenin from Polygala senega and Polygala tenuifolia. Tetrahedron letters, 1967, vol. (52), p. 5303-6.
- TSUKITANI, Y., SHOJI, J. STUDIES ON CONSTITUENTS OF SENEGAE RADIX .3. STRUCTURES OF SENEGIN-III AND SENEGIN-IV, SAPONINS FROM POLYGALA SENEGA LINNE VAR LATIFOLIA TORRY ET GRAY . Chemical & pharmaceutical bulletin, 1973, vol. 21, no. 7, p. 1564-1574.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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